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Displaying drugs 10526 - 10550 of 12312 in total

Glucoraphanin

Glucoraphanin is under investigation in clinical trial NCT01879878 (Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]).
Investigational
Matched Synonyms: … 4-methylsulfinylbutyl glucosinolate …
Matched Iupac: … {[(E)-(5-methanesulfinyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}pentylidene …

Mefuparib

Investigational
Matched Synonyms: … 5-fluoro-2-(4-((methylamino)methyl)phenyl)-7-benzofurancarboxamide …
Matched Iupac: … 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide …

Aranidipine

Aranidipine is a novel dihydropyridine derivative that gives rise to two active metabolites (M-1α and M-1β) that exhibit hypotensive activity. It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate. It was developed by Maruko Seiyaku, introduced by Taiho and launched in Japan in 1997.
Experimental
Matched Iupac: … 3-methyl 5-(2-oxopropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … It is a calcium antagonist with the formula methyl 2-oxopropyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tafolecimab

Tafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia).
Investigational

Bifeprunox

Bifeprunox is a novel atypical antipsychotic agent which, along with SLV313, aripiprazole and SSR-181507 combines minimal D2 receptor agonism with 5-HT receptor agonism.
Investigational
Matched Iupac: … 7-[4-({[1,1'-biphenyl]-3-yl}methyl)piperazin-1-yl]-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Salts cas: … 350992-13-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Zinc picolinate

Zinc picolinate is a zinc salt of picolinic acid. It is available as OTC dietary supplements as a source of zinc to treat and prevent zinc deficiency. The absorption of zinc after oral administration of zinc picolinate is shown to be effective.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Lecozotan

Lecozotan has been used in trials studying the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … 4-cyano-N-[(2R)-2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]propyl]-N-(pyridin-2-yl)benzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

AG-24322

AG-024322 has been used in trials studying the treatment of Neoplasms and Lymphoma, Non-Hodgkin.
Investigational
Matched Iupac: … ({5-[3-(4,6-difluoro-1H-1,3-benzodiazol-2-yl)-1H-indazol-5-yl]-4-methylpyridin-3-yl}methyl)(ethyl)amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Phenglutarimide

Experimental
Matched Iupac: … 3-[2-(diethylamino)ethyl]-3-phenylpiperidine-2,6-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

AZD-6482

AZD-6482 is under investigation in clinical trial NCT00688714 (Study to Investigate Safety and Tolerability of a Single Dose of AZD6482).
Investigational
Matched Iupac: … 2-{[(1R)-1-[7-methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino}benzoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Class Ia Phosphatidylinositol 3-Kinase, antagonists & inhibitors …

SUVN-502

SUVN-502 is a novel, potent, safe, highly selective and orally active antagonist at a central nervous system serotonin receptor site 5-HT6 intended for treatment of cognitive disorders such as Alzheimer’s and Schizophrenia, an unmet medical need.
Investigational
Matched Iupac: … 1-(2-bromobenzenesulfonyl)-5-methoxy-3-[(4-methylpiperazin-1-yl)methyl]-1H-indole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

TT-232

Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma).
Investigational
Matched Iupac: … (2S,3R)-2-{[(4R,7S,10R,13S,16R)-16-[(2R)-2-amino-3-phenylpropanamido]-7-(4-aminobutyl)-13-[(4-hydroxyphenyl ... )methyl]-10-[(1H-indol-3-yl)methyl]-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraazacycloheptadecan-4 ... -yl]formamido}-3-hydroxybutanamide …

Methyl-O3-(Alpha-D-Mannose)-Alpha-D-Mannose

Experimental
Matched Iupac: … (2R,3S,4S,5S,6R)-2-{[(2R,3R,4S,5S,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-4-yl]oxy}-6-(hydroxymethyl …

Quingestanol acetate

Experimental
Matched Synonyms: … Norethindrone acetate 3-cyclopentyl enol ether …
Matched Iupac: … ,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate ... (1R,3aS,3bR,9aR,9bS,11aS)-7-(cyclopentyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H …

Ciluprevir

The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Investigational
Matched Iupac: … yl}quinolin-4-yl)oxy]-2,15-dioxo-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-ene-4-carboxylic acid ... ,14S,18R)-14-{[(cyclopentyloxy)carbonyl]amino}-18-[(7-methoxy-2-{2-[(propan-2-yl)amino]-1,3-thiazol-4- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Glufosfamide

Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Vistusertib

Vistusertib is under investigation for the treatment of Advanced Gastric Adenocarcinoma.
Investigational
Matched Iupac: … 3-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-N-methylbenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Atevirdine

Atevirdine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … N-ethyl-2-[4-(5-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]pyridin-3-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Verucerfont

Verucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.
Investigational
Matched Iupac: … 3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

MK-5108

MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.
Investigational
Matched Iupac: … (1r,4r)-4-(3-chloro-2-fluorophenoxy)-1-({6-[(1,3-thiazol-2-yl)amino]pyridin-2-yl}methyl)cyclohexane-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ondelopran

Ondelopran has been used in trials studying the treatment of Alcohol Dependence.
Investigational
Matched Iupac: … 6-[2-fluoro-4-({[2-(oxan-4-yl)ethyl]amino}methyl)phenoxy]pyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Fazadinium bromide

Experimental
Matched Iupac: … 3-methyl-1-[(E)-2-{3-methyl-2-phenyl-1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium-1-yl}diazen-1-yl]-2-phenyl ... -1H-4lambda5-imidazo[1,2-a]pyridin-4-ylium dibromide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BMS-986141

BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
Investigational
Matched Iupac: … 4-(4-{[(6-methoxy-2-{2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl}-1-benzofuran-4-yl)oxy]methyl}-1,3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ziresovir

Ziresovir is under investigation in clinical trial NCT03699202 (Anti-RSV Study in Chinese Patients (ASCENT)).
Investigational
Matched Iupac: … 4-(4-{[(3-aminooxetan-3-yl)methyl]amino}-6-methylquinazolin-2-yl)-2,3,4,5-tetrahydro-1lambda6,4-benzothiazepine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Troclosene

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10526 - 10550 of 12312 in total