Displaying drugs 10701 - 10725 of 11559 in total
Pelitrexol
Pelitrexol has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … (2S)-2-[(5-{2-[(6S)-2-amino-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidin-6-yl]ethyl}-4-methylthiophen …
Lanabecestat
Lanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).
Investigational
Matched Iupac: … (1r,1'R,4R)-4-methoxy-5''-methyl-6'-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3'H-dispiro[cyclohexane-1,2'-indene ... -1',2''-imidazol]-4''-amine …
Dopastatin
Dopastatin is under investigation in clinical trial NCT04335357 (TBR-760 in Adult Patients With Non-functioning Pituitary Adenomas).
Investigational
Matched Iupac: … (2R)-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S,2R)-1-carbamoyl-2-hydroxypropyl]carbamoyl}- ... (2R,4R,7R)-6-propyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),9,12(16),13-tetraen-4- ... 7-ethyl-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17 …
Methylthioinosine
An analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.
Experimental
Matched Synonyms: … 6-S-methyl-6-thioinosine …
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methylsulfanyl)-9H-purin-9-yl]oxolane-3,4-diol …
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methylsulfanyl)-9H-purin-9-yl]oxolane-3,4-diol …
PF-03814735
PF-03814735 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … N-{2-[(1R,8S)-4-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-11-azatricyclo[6.2.1.0 …
Rotigaptide
Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … -2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)propanamide ... (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine …
TAS-117
TAS-117 is under investigation in clinical trial NCT03017521 (K-BASKET, TAS-117, PI3K/AKT Gene Aberration).
Investigational
Matched Iupac: … (1r,3s)-3-amino-1-methyl-3-(4-{5-phenyl-8-oxa-3,6,12-triazatricyclo[7.4.0.0^{2,6}]trideca-1(13),2,4,9,11 ... -pentaen-4-yl}phenyl)cyclobutan-1-ol …
Rivenprost
Rivenprost is under investigation in clinical trial NCT00296556 (Therapeutic Study of ONO-4819CD for Ulcerative Colitis).
Investigational
Matched Iupac: … methyl 4-({2-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(methoxymethyl)phenyl]but-1-en-1-yl]-5-oxocyclopentyl …
Acylated ceftazidime
Experimental
Matched Iupac: … ]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid ... (2R)-2-[(1R)-1-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-oxoethyl …
9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE
Experimental
Matched Iupac: … {[(2S,3aR,4R,6S,6aS)-4-(hydroxymethyl)-6-{4-oxo-1H,4H,5H-pyrrolo[3,2-d]pyrimidin-7-yl}-tetrahydro-2H-furo …
Prednimustine
Prednimustine has been used in trials studying the treatment of Lymphoma.
Investigational
Matched Iupac: … -3,6-dien-14-yl]-2-oxoethyl 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoate ... 2-[(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca …
α-Methylfentanyl
α-Methylfentanyl is an analog of fentanyl with opioid analgesic properties.
Illicit
Matched Iupac: … N-phenyl-N-[1-(1-phenylpropan-2-yl)piperidin-4-yl]propanamide …
Quinonoid 7,8-Tetrahydrobiopterin
Experimental
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4,6,7-tetrahydropteridin-4-one …
Fenoxaprop-ethyl
Fenoxaprop-ethyl (organic nitrate combined with L-arginine), is an oral proprietary nitrate therapeutic shown to induce coronary vasodilation while overcoming the significant problem of drug tolerance. Fenoxaprop-ethyl has been investigated to treat chronic angina, the chest pain that occurs from inadequate blood flow to the coronary arteries around the heart.
Investigational
Matched Iupac: … ethyl 2-{4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy}propanoate …
Tetomilast
Tetomilast has been used in trials studying the treatment of Crohn Disease, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid …
Gallium maltolate
Gallium maltolate is Titan’s novel oral agent in development for the potential treatment of chronic bacterial infections, bone disease and cancer.
Investigational
Matched Iupac: … gallium(3+) ion tris(2-methyl-4-oxo-4H-pyran-3-olate) …
Dotarizine
Investigational
Matched Iupac: … 1-(diphenylmethyl)-4-[3-(2-phenyl-1,3-dioxolan-2-yl)propyl]piperazine …
Pidotimod
Pidotimod is a synthetic dipeptide with immunomodulatory properties.
Experimental
Matched Iupac: … (4R)-3-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid …
Melarsomine
Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide. It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection.
Experimental
Vet approved
Matched Iupac: … N2-(4-{bis[(2-aminoethyl)sulfanyl]arsanyl}phenyl)-1,3,5-triazine-2,4,6-triamine …
Matched Salts cas: … 89141-50-4 …
Matched Salts cas: … 89141-50-4 …
Iguratimod
Iguratimod is under investigation in Rheumatoid Arthritis.
Investigational
Matched Iupac: … N-(7-methanesulfonamido-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide …
MSX-122
MSX-122 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Iupac: … N-[(4-{[(pyrimidin-2-yl)amino]methyl}phenyl)methyl]pyrimidin-2-amine …
AKN-028
AKN-028 has been used in trials studying the treatment of Acute Myeloid Leukemia.
Investigational
Matched Iupac: … N2-(1H-indol-5-yl)-6-(pyridin-4-yl)pyrazine-2,3-diamine …
Deoxyspergualin
Deoxyspergualin has been used in trials studying the treatment of Lupus Nephritis, Chronic Rejection, and Diabetes Mellitus, Type 1.
Investigational
Matched Iupac: … N-[(S)-({4-[(3-aminopropyl)amino]butyl}carbamoyl)(hydroxy)methyl]-7-carbamimidamidoheptanamide …
Ripasudil
Ripasudil, as hydrochloride hydrate (K-115), is a specifc Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor used for the treatment of glaucoma and ocular hypertension. It was first approved for treatment in Japan in September 2014. This medication is available in the form of a 0.4% eye drop solution under the...
Experimental
Matched Iupac: … 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …
Displaying drugs 10701 - 10725 of 11559 in total