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Displaying drugs 1051 - 1075 of 1334 in total

Anthrax vaccine

Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Description: … [L47561] There are currently 2 anthrax vaccines approved by the FDA: BioThrax in August 15, 2016 and ... Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high ... an Anthrax terrorist attack or for pre-exposure prophylaxis of personnel going to specific arenas around …
Matched Products: … BioThrax (Anthrax Vaccine Adsorbed) Supension for Injection 50?g/dose (nominal) …

3-[2,6,8-Trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate

Experimental
Matched Name: … 3-[2,6,8-Trioxo-9-[(2R,3S,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate …

3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate

Experimental
Matched Name: … 3-[2,6,8-Trioxo-9-[(2R,3R,4R)-2,3,4,5-tetrahydroxypentyl]-3H-purin-7-yl]propyl dihydrogen phosphate …

Bicisate

Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Matched Description: … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved …
Matched Products: … NEUROLITE KIT FOR THE PREPARATION OF Tc99m BICISATE FOR INJECTION …

Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)

Approved
Matched Products: … IXIARO Suspension for Injection 0.5ml in pre-filled syringe …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for ... 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months ... increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Description: … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. …
Matched Categories: … Enzymes and Coenzymes ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … FASTURTEC POWDER FOR SOLUTION FOR INFUSION 1.5 mg/vial …

Gadoxetic acid

Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Description: … hepatobiliary phase and thus has different pharmacokinetic and pharmacodynamic properties compared to ... forms a stable complex with it to make up the drug. ... , gadoxetate disodium, is used for intravenous injection. …
Matched Products: … Primovist 0.25 mmol/ml Solution for injection ... PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTION …

Antithrombin III human

A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Anbinex Powder For Injection 500 I.U. ... Anbinex Powder For Injection 1000 I.U. …

Amphotericin B

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Description: … The antibiotic is without effect on bacteria, rickettsiae, and viruses. ... Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. ... Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antimycotics for Systemic Use …
Matched Products: … AMPHOTRET FOR INJECTION USP 50MG ... Amphotericin B for Injection, USP ... AMBISOME FOR INJECTION 50 mg/vial …

Cefazolin

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
Approved
Matched Description: … It attains high serum levels and is excreted quickly via the urine. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CEFAZOLIN ALVOGEN POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Cefazolin for Injection ... Cefazolin for Injection USP …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … There is no specific treatment for hepatitis. ... The hepatitis B virus induces a severe form of viral hepatitis. ... the chronic complications such as chronic active hepatitis and cirrhosis. …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Engerix-B 20 Adult Dose Suspension for Injection ... Engerix-B 10 Junior Dose Suspension for Injection ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Description: … for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and ... infarction (non-reversible defects); and 2) evaluating myocardial function and developing information ... for use in patient management decisions. …
Matched Categories: … Indicators and Reagents …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi …

Nefopam

Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
Approved
Investigational
Matched Description: … Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. ... Nefopam has been investigated for the prevention of Kidney Transplantation. …
Matched Products: … ACUPAN SOLUTION FOR INJECTION 20MG/2ML …

3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE

Experimental
Matched Name: … 3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE …
Matched Iupac: … (2S,3R)-3-formyl-N,2-dihydroxy-5-methylhexanamide …

Imidapril

Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Investigational
Matched Description: … Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant. …
Matched Products: … PRILIUM 150MG POWDER FOR ORAL SOLUTION …

Arsenic trioxide

Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Description: … The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Arsenic Trioxide for Injection ... Teva-arsenic Trioxide for Injection ... Arsenic Trioxide Solution for Injection …

Clostridium botulinum

Experimental
Matched Products: … DYSPORT FOR INJECTION 300u/vial ... DYSPORT FOR INJECTION 500 u/vial ... NEURONOX LYOPHILIZED POWDER FOR INJECTION 100 UNITS/VIAL …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Description: … pain relief and adjunctive to an anaesthetic. ... causes respiratory depression and analgesia. ... Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Reig Jofre 5mg Powder for Concentrate for Solution for Injection or Infusion ... Remifentanil for Injection ... ULTIVA FOR INJECTION 1 mg/vial …

Filgrastim

Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … has an N-terminal methionine added in the sequence for expression in _E. ... peripheral blood for collection by leukapheresis in patients undergoing peripheral blood progenitor ... cell collection and therapy. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Nivestim 120 mcg/0.2 ml solution for injection/infusion ... Nivestim 300mcg/0.5ml solution for Injection/Infusion ... Nivestim 120mcg/0.2mL Solution for Injection/Infusion …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. ... [L40928] It is also used for high-conditioning before hematopoietic stem cell transplant. ... [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group …
Matched Mixtures name: … Melphalan for Injection ... Melphalan for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan for Injection ... ALKERAN FOR INJECTION 50 mg/vial …

Dactinomycin

A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … DACTINOMYCIN FOR INJECTION 0.5 mg/vial …

Verteporfin

Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: CL-315555 and CL-315585. It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red...
Approved
Investigational
Matched Description: … It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form ... as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: [CL-315555] and ... Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light …
Matched Products: … VISUDYNE FOR INJECTION 15 mg/vial …

Rofecoxib

Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Description: … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and ... doses of 125, 25, and 50 mg is approximately 93%. ... The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … REOX 25 MG FORT TABLET, 14 ADET ... REOX 25 MG FORT TABLET, 28 ADET …

Carbocisteine

Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Description: … [L32383] Several licenses for this drug were withdrawn following serious and fatal paradoxical effects ... [A230993] Carbocisteine is currently not FDA or Health Canada approved, but is approved for use in Asia ... Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other …
Matched Mixtures name: … AXIM TOSTHERAPY FORTE® …
Matched Categories: … Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Matched Products: … MUKO-S FORT 375 MG TABLET , 20 ADET ... MUKOTIK FORT 375 MG TABLET, 20 ADET ... MUKOTIK FORT 375 MG TABLET, 50 ADET …
Displaying drugs 1051 - 1075 of 1334 in total