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Displaying drugs 1051 - 1075 of 1510 in total

Tozinameran

The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Description: … [L26956] Fact sheets for caregivers, recipients, and healthcare providers are now available. ... Comirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older. ... The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Comirnaty 3mcg Concentrate for Dispersion for Injection ... Comirnaty Omicron XBB.1.5 10 micrograms/dose Dispersion for Injection ... Comirnaty Omicron XBB.1.5 30 micrograms/dose Dispersion for Injection …

Styphnolobium japonicum flower bud

Styphnolobium japonicum flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Products: … BARAMO for O ily Scalp ... BARAMO for Normal Scalp ... BARAMO Scalp Serum for Normal Scalp …

Pegaspargase

Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia. Asparagine is an amino acid that is vital for cell survival. In humans, most normal tissues can produce asparagine through the action of asparagine synthetase. However, leukemia...
Approved
Investigational
Matched Description: … Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine ... However, leukemia cells have low levels of this enzyme and depend on exogenous sources. ... reducing immune detection, and it also increases the half-life of L-asparaginase. …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ONCASPAR POWDER FOR SOLUTION FOR INJECTION/INFUSION 750 U/ML ... Oncaspar 750 U/ml powder for solution for injection/infusion …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … HYCAMTIN (POWDER FOR SOLUTION FOR INFUSION) ... TOCANTIN POWDER FOR SOLUTION FOR INFUSION 4MG ... TOCANTIN POWDER FOR SOLUTION FOR INFUSION 4 MG/VIAL …

Phellodendron amurense bark

Phellodendron amurense bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Products: … Jayeonbi Secret Care Mist for Lady Y-zone Mist ... Jayeonbi Secret Care Mist for Men Y-zone Mist ... JAYEONBI Secret Care Mist For Lady Y-zone Mist …

Sarilumab

Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL-6. Sarilumab was developed by Sanofi and Regeneron Pharmaceuticals, Inc; it was US FDA-approved in May 2017 and followed...
Approved
Investigational
Matched Description: … soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling cascades of IL ... in May 2017 and followed by EU approval in June 2017 for the treatment of moderate to severe rheumatoid ... human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … KEVZARA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG ... KEVZARA Solution for Injection in Pre-filled Pen 150mg ... KEVZARA Solution for Injection in Pre-filled Pen 200mg …

Zoledronic acid

Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and ... of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. …
Matched Categories: … zoledronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... Drugs for Treatment of Bone Diseases …
Matched Products: … ZOVA CONCENTRATE FOR SOLUTION FOR INFUSION 4MG/5ML ... ZOLETEM CONCENTRATE FOR SOLUTION FOR INFUSION 4MG/5ML ... ZOBONE CONCENTRATE FOR SOLUTION FOR INFUSION 4MG/5ML …

Avelumab

Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … ] and Health Canada,[L48171] respectively. ... programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and ... [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BAVENCIO CONCENTRATE FOR SOLUTION FOR INFUSION 200MG/10ML ... BAVENCIO 200 mg/10mL concentrate for solution for infusion …

Alirocumab

Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which...
Approved
Matched Description: … high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and ... FDA approval was contingent on the completion of further clinical trials to better determine efficacy and ... Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … PRALUENT 150 MG/ML (SOLUTION FOR INJECTION IN PRE-FILLED PEN) ... PRALUENT 75 MG/ML (SOLUTION FOR INJECTION IN PRE-FILLED PEN) ... PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/ML …

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … MTC-DOX for Injection …
Matched Description: … Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … DOXABIN POWDER FOR SOLUTION FOR INJECTION 10MG/VIAL ... DOXABIN POWDER FOR SOLUTION FOR INJECTION 50MG/VIAL ... DOXOCCORD CONCENTRATE FOR SOLUTION FOR INFUSION 2 MG/ML …

Lixisenatide

Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM). It is sold by Sanofi-Aventis under the brand name Adlyxin in the US and Lyxumia in the EU. Adlyxin recieved FDA approval July 28, 2016.
Approved
Matched Description: … It is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU. …
Matched Mixtures name: … LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... LYXUMIA SOLUTION FOR INJECTION IN PRE-FILLED PEN 10MCG AND 20MCG (50mcg/mL and 100mcg/mL) ... Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide …
Matched Products: … LYXUMIA (SOLUTION FOR INJECTION 10 MCG) ... LYXUMIA (SOLUTION FOR INJECTION 20 MCG) ... Lyxumia 20mcg Solution for Injection …

Golimumab

Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Matched Description: … Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients ... Golimumab binds and inhibits soluble and transmembrane human TNFα. ... Additionally in children and adolescents taking golimumab, there have been lymphoma and other malignancies …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Biologics for Rheumatoid Arthritis Treatment …
Matched Products: … Concentrate for Solution for Infusion 12.5mg/1 ml ... SIMPONI IV 12.5mg/1ml Concentrate for Solution for Infusion ... SIMPONI SOLUTION FOR INJECTION …

Panitumumab

Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent. Panitumumab was granted FDA approval on 27 September 2006.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … Vectibix Concentrate for Solution for Infusion 100 mg/vial ... Vectibix 100mg Concentrate for Solution for Infusion …

Benralizumab

Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils and basophils. It inhibits the binding of IL-5 as well as the hetero-oligomerization of the alpha and beta subunits of the IL-5R,...
Approved
Investigational
Matched Description: … , macrophages and neutrophils. ... It is an afucosylated IgG which gives it high affinity for the FcγRIIIα receptor in natural killer cells ... global biologic research and development arm. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs for Obstructive Airway Diseases …
Matched Products: … Fasenra 30 mg solution for injection in pre-filled syringe ... Fasenra 30mg Solution for Injection in Pre-filled Pen ... FASENRA SOLUTION FOR INJECTION 30MG/ML (AUTOINJECTOR PEN) …

Eravacycline

Eravacycline, known as Xerava by Tetraphase Pharmaceuticals, is a fully synthetic fluorocycline antibiotic of the tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and facultative bacteria. This includes most of those bacteria resistant to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic...
Approved
Investigational
Matched Description: … carbapenem-resistant Enterobacteriaceae, and the majority of anaerobic pathogens [A38683]. ... tetracycline class with activity against clinically significant gram-negative, gram-positive aerobic, and ... to cephalosporins, fluoroquinolones, β-lactam/β-lactamase inhibitors, multidrug-resistant strains, and …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … XERAVA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG PER VIAL …

Cimicoxib

Cimicoxib is a selective COX-2 inhibitor being developed by Affectis as a treatment for depression and schizophrenia. If approved, Cimicoxib would be the first drug in decades to treat depression by a new mechanism of action.
Investigational
Matched Description: … Cimicoxib is a selective COX-2 inhibitor being developed by Affectis as a treatment for depression and …
Matched Products: … Cimalgex 30mg chewable tablets for dogs ... Cimalgex 80mg chewable tablets for dogs ... Cimalgex 8mg chewable tablets for dogs …

Avalglucosidase alfa

Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe ... muscle weakness, which leads to premature death and debilitating effects on people’s lives. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … NEXVIAZYME 100mg Powder for Concentrate for Solution for Infusion …

Paclitaxel

Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … Paclitaxel protein-bound particles for injection suspension …
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound ... Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar …
Matched Products: … Aclipak Concentrate for Solution for Infusion 6mg/ ml ... FONKOPAC CONCENTRATE FOR SOLUTION FOR INFUSION 6MG/ML ... ACLIPAK 6 MG/ ML CONCENTRATE FOR SOLUTION FOR INFUSION …

Etelcalcetide

Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Description: … Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism ( ... Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Calcium Homeostasis ... Calcium-sensing Receptor Agonist ... Increased Calcium-sensing Receptor Sensitivity …
Matched Products: … PARSABIV SOLUTION FOR INJECTION 5 mg/mL ... Parsabiv 5mg solution for injection ... PARSABIV SOLUTION FOR INJECTION 2.5 mg/0.5 mL …

Durvalumab

Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint inhibitor for cancer treatment. Produced by recombinant DNA technology in Chinese Hamster Ovary (CHO) cell suspension culture, durvalumab is a programmed death-ligand 1 (PD-L1) blocking antibody that works to promote normal immune responses that attack tumour...
Approved
Investigational
Matched Description: … Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody and a novel immune-checkpoint ... unresectable non-small cell lung cancer (NSCLC), only if PD-L1 is expressed in ≥ 1% of tumour cells and ... ] and either [carboplatin] or [cisplatin] as first-line treatment of patients with extensive-stage small …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … IMFINZI CONCENTRATE FOR SOLUTION FOR INFUSION 50 MG/ML ... IMFINZI CONCENTRATE FOR SOLUTION FOR INTRAVENOUS INFUSION 50 MG/ML …

Deferoxamine

Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Approved
Investigational
Matched Description: … It forms iron complexes and is used as a chelating agent, particularly in the mesylate form. …
Matched Categories: … Iron Chelating Agents ... Iron Chelating Activity …
Matched Products: … Desferal 500mg Powder for Solution for Injection ... Deferoxamine Mesylate for Injection ... DBL DESFERRIOXAMINE MESYLATE FOR INJECTION BP 500 mg/vial …

Gemtuzumab ozogamicin

Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp. calichensis. Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody [FDA Label]. The antibody is specifically...
Approved
Investigational
Matched Description: … It is also indicated for the treatment of patients aged 2 years and older with CD33-positive AML who ... By binding to the CD33 antigen on tumors, the cytotoxic agent blocks the growth of cancerous cells and ... with CD33-positive AML in first relapse who are 60 years of age or older and who are not considered …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … MYLOTARG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 5MG/VIAL …

Inotuzumab ozogamicin

Inotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin dimethylhydrazide. The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly releases N-acetyl-gamma-calicheamicin dimethylhydrazide, which produces cytotoxic effects. Inotuzumab ozogamicin was first...
Approved
Investigational
Matched Description: … [A20352] The antibody portion of the drug binds to CD22 receptors expressed on leukemic B cells and intracellularly ... [A20352] Inotuzumab ozogamicin was first approved by the European Commission in June 2017 for the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … BESPONSA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 1MG/VIAL …

Denosumab

Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption via inhibiting RANK-mediated activation of osteoclasts. It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss. Chemically, it consists of 2 heavy...
Approved
Matched Description: … receiving androgen deprivation therapy for non-metastatic prostate cancer and women at high risk for ... fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in September 2011 and in men ... It is the first and currently the only RANKL inhibitor approved to prevent osteoclast-mediated bone loss …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Drugs for Treatment of Bone Diseases …
Matched Products: … XGEVA 120mg Solution for Injection ... XGEVA Solution for Injection 120 mg/vial ... Prolia Solution for Injection 60mg Pre-filled Syringe …

Canakinumab

Canakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype subclass. It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated. Both heavy...
Approved
Investigational
Matched Description: … Canakinumab is marketed under the brand name Ilaris and indicated for patients 4 years of age and older ... part of the Cryopyrin-Associated Periodic Syndromes (CAPS) as well as for patients 2 years of age and ... and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Ilaris Powder for Solution for Injection 150mg/vial ... ILARIS 150MG POWDER FOR SOLUTION FOR INJECTION …
Displaying drugs 1051 - 1075 of 1510 in total