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Displaying drugs 1051 - 1075 of 1089 in total
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … fragment) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 (synthetic human
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With …
scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA. Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Investigational
Matched Synonyms: … recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human
Matched Description: … recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c2g4 .kappa. ... Immunoglobulin g1, anti-(ebolavirus glycoprotein) (human-mus musculus monoclonal c2g4 heavy chain), disulfide …
Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).
Investigational
Matched Synonyms: … Dna (recombinant adeno-associated virus 6 vector pf-07055480 human b-domain-deleted blood-coagulation …
Matched Description: … fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid- …
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Synonyms: … Phosphoric acid, monosodium salt, anhydrous …
Matched Mixtures name: … Ionosol and Dextrose ... Ionosol B and Dextrose ... Ionosol MB and Dextrose …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Potassium Salt ... Phosphate salts ... Blood Substitutes and Perfusion Solutions …
Investigational
Matched Synonyms: … Ex-vivo-expanded autologous keratinocytes transduced with retroviral vector containing the human COL7A1 …
Investigational
Matched Synonyms: … ) PATIENTS, TRANSDUCED EX VIVO WITH A SELF-INACTIVATING LENTIVIRAL VECTOR, ENCODING CODON-OPTIMIZED HUMAN
Investigational
Matched Synonyms: … Vasoactive intestinal peptide (human) …
Matched Categories: … Nerve Tissue Proteins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Dynorphin is under investigation in clinical trial NCT00000244 (Effects of Dynorphin 1-13 on Heroin Addiction - 1).
Investigational
Matched Synonyms: … Dynorphin a (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nerve Tissue Proteins …
Investigational
Matched Synonyms: … HER2) (human-Mus musculus monoclonal Amab788 γ1-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G1 [121-(4-acetylphenylalanine),de-450-lysine], anti-(human epidermal growth factor receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … acetyl-n5-hydroxy-l-ornithyl-n5-acetyl-n5-hydroxy-l-ornithyl-n5-acetyl-n5-hydroxy-l-ornithyl), aluminum salt
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Synonyms: … Adrenocorticotropic hormone fragment 1-24 human, rat …
Matched Categories: … Nerve Tissue Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues …
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … impact on quality of life and poses a significant burden on the healthcare system. ... Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Matched Products: … METOCLOPRAMIDE SALF
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and ... firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD45 antigen) (mus musculus monoclonal BC8 gamma1-chain), disulfide with …
Investigational
Matched Synonyms: … Allogeneic bone marrow derived human mesenchymal stem cells …
Investigational
Matched Synonyms: … Human T-cell receptor (BV5S2)peptide …
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … It is the principal end product of protein catabolism and constitutes about one half of the total urinary …
Matched Mixtures name: … . - Salbe + Nagelset ... Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% …
Matched Categories: … Blood and Blood Forming Organs ... Emollients and Protectives ... Blood Substitutes and Perfusion Solutions …
Matched Products: … BASODEXAN 100MG/G SALBE
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …
Neuradiab is under investigation in clinical trial NCT00615186 (Glioblastoma Multiforme (GBM) Locoregional Agent Survival Study - Anti-tenascin Radiolabeled Antibody Therapy).
Investigational
Matched Synonyms: … Moab, 81c6, murine, iodine-I-131 radiolabeled, to human glioma …
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched International brands: … Huma-Zolamide …
Matched Description: … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures ... to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Synonyms: … Human herpesvirus 3 live (attenuated) antigen …
Matched Description: … and post-herpetic neuralgia. ... efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients ... Varivax for the prevention of chickenpox in individuals 12 months of age and older. …
Matched Mixtures name: … PROQUAD® ( Measles, Mumps, Rubella AND Varicella (Oka/Merck) Virus Vaccine Live, MSD) LYOPHILIZED VACCINE …
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 1051 - 1075 of 1089 in total