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Displaying drugs 1051 - 1075 of 1416 in total

Betaine

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Description: … The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment ... occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and …
Matched Mixtures name: … Betaine HCl and Pepsin ... Rocky Mountain Multiple Vit and Min Mega Tab ... Glutamic Acid Pepsin and Betaine Tablets …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives …
Matched Products: … Betaine Anhydrous For Oral Solution ... Betaine Anhydrous for Oral Solution …

Avibactam

Avibactam is a non-β-lactam β-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metronidazole, and the treatment of complicated urinary tract infections, including pyelonephritis caused by antibiotic resistant-pathogens,...
Approved
Matched Description: … As there is limited clinical safety and efficacy data, Avycaz should be reserved for patients over 18 ... infections in combination with metronidazole, and the treatment of complicated urinary tract infections ... This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal …
Matched Products: … ZAVICEFTA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 2G/0.5G …

Olipudase alfa

Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... storage disease caused by mutations in the SMPD1 gene, leading to a deficiency in acid sphingomyelinase and ... to hydrolyze sphingomyelin accumulated in body tissues, such as the lungs, liver, spleen, kidneys, and …
Matched Categories: … Phosphoric Diester Hydrolases ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … XENPOZYME 20MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …

Trastuzumab deruxtecan

Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. It is classified as an antibody-drug conjugate. The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of...
Approved
Investigational
Matched Description: … The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from ... A188988] Trastuzumab deruxtecan was developed by Daiichi Sankyo in collaboration with AstraZeneca and ... Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ENHERTU POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL ... Daptomycin for Injection ... Daptomycin for Injection RF …

Tocilizumab

Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and ... [L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December ... autoimmune disorders, such as different types of arthritis and cytokine release syndrome. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Biologics for Rheumatoid Arthritis Treatment ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … Actemra Concentrate for Solution for Infusion 20mg/ml ... ACTEMRA 20 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION. ... ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE) …

Ganciclovir

An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Categories: … Ganciclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CYMEVENE 500MG powder for concentrate for solution for infusion ... Ganciclovir for Injection ... GANCICLOVIR SODIUM FOR INJECTION …

Insulin glargine

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin ... The resulting protein is soluble at pH 4 and forms microprecipitates at physiological pH 7.4 allowing ... 1 and Type 2 Diabetes. …
Matched Mixtures name: … Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/ML ... SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 33MCG/ML …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … solution for Injection in vial 100 Units/ml ... Glaritus 100 IU/mL Solution for injection ... BASALOG 100 IU/mL, SOLUTION FOR INJECTION IN A VIAL …

Voriconazole

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [ …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VFEND (200 MG POWDER FOR SOLUTION FOR INFUSION ... VORICONAZOLE ALVOGEN (200 MG POWDER FOR SOLUTION FOR INFUSION) ... Voriconazole ADVAGEN powder for solution for infusion 200mg …

Fosgemcitabine palabenamide

NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … 3R,5R)-5-(4-AMINO-2-OXO-PYRIMIDIN-1-YL)-4,4-DIFLUORO-3-HYDROXY-TETRAHYDROFURAN-2-YL)METHOXY-PHENOXY-PHOSPHORYL …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Alemtuzumab

Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic ... The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing ... The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … LEMTRADA Concentrate for Solution for Infusion 12 mg ... LEMTRADA CONCENTRATE FOR SOLUTION FOR INFUSION 12 MG/ 1.2 ML …

Peginterferon alfa-2b

Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … 41% for genotype 1 and 75% for genotypes 2-6 after 48 weeks of treatment. ... development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Treatments for Hepatitis C …
Matched Products: … PEG-INTRON CLEARCLICK FOR INJECTION 80 mcg/0.5 ml ... PEG-INTRON CLEARCLICK FOR INJECTION 100 mcg/0.5 ml ... PEG-INTRON CLEARCLICK for Injection 50 mcg/0.5 ml …

Phenothrin

Experimental
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Products: … BI-SOL FORT SAMPUAN, 60 ML …

Nifuroxazide

Experimental
Matched Mixtures name: … METRO FORT …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DIAFURYL FORT 200 MG KAPSÜL, 16 ADET ... DIAFURYL FORT 200 MG KAPSÜL, 24 ADET …

Paliperidone

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Description: … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic ... therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and ... extended-release tablet, a once-monthly intramuscular injection, an every-three-month intramuscular injection, and …
Matched Products: … INVEGA Sustenna Prolonged Release Suspension for IM Injection 25mg/0.25 ml ... INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 ml ... INVEGA Sustenna Prolonged Release Suspension for IM Injection 75mg/0.75ml …

Hepatitis B immune globulin

Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Antiinfectives for Systemic Use …
Matched Products: … HEPATECT CP SOLUTION FOR INFUSION 50 IU/ML ... Niuliva Solution For Infusion 250 I.U./ml ... ZUTECTRA SOLUTION FOR INJECTION 500 IU/ML …

Levosimendan

Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. It also relaxes vascular smooth muscle by opening adenosine triphosphate sensitive potassium channels. Levosimendan is used to manage acutely decompensated congestive heart failure.
Approved
Investigational
Matched Products: … SIMDAX 2.5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION ... Simdax 2.5 mg/ml concentrate for solution for infusion. …

Isavuconazonium

Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed by Astellas under the brand Cresemba. It is the prodrug form of isavuconazole, the active moiety, and it...
Approved
Investigational
Matched Description: … [A38834] It is the prodrug form of isavuconazole, the active moiety, and it is available in oral and ... 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed ... Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July …
Matched Salts name: … Isavuconazonium sulfate …
Matched Categories: … Isavuconazole and Prodrugs …
Matched Products: … CRESEMBA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200MG …

Ranibizumab

Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … , and Health Canada respectively. ... [L41429] It is marketed under the brand names LUCENTIS and SUSVIMO. ... after [bevacizumab], another anti-VEGF anticancer drug, was discovered to inhibit neovascularization and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Lucentis 10mg/ml Solution for Injection ... ACCENTRIX 10MG/ML SOLUTION FOR INJECTION ... LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE …

Belimumab

Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and ... [A251520] It is currently used to treat SLE and lupus nephritis.[L42630] ... [L42630] BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Benlysta Powder for Solution for Infusion 400mg ... Benlysta Powder for Solution for Infusion 120mg …

Pegfilgrastim

Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … pharmacokinetic profile and conditions of use. ... than 20% in many readily used chemotherapy regimens,[A248855] infections pose risks of hospitalization and ... [A29,A187607] Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Pelgraz 6 mg solution for injection in a pre-filled syringe ... Pelgraz Solution for Injection in pre-filled syringe 6mg/0.6mL ... Filpegla 6 mg / 0.6 mL Solution for Injection in Pre-filled Syringe …

Lanreotide

Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. Lanreotide is manufactured by the company, Ipsen...
Approved
Matched Description: … Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed ... It is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. ... Lanreotide was first approved for use in the United States by the FDA on August 30, 2007. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg ... Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 60 mg ... Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 90 mg …

Streptokinase

Streptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … Streptokinase Karma 1 500 000 IU Powder for Solution for Infusion …

Pentetic acid

Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Description: … DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Products: … TECHNESCAN DTPA FOR INJECTION 20.8 mg/vial ... Kit for the Preparation of Technetium Tc 99m Pentetate Injection …

Semaglutide

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Description: … Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection in December ... The use of salt forms of semaglutide, including semaglutide sodium and semaglutide acetate, has not been ... and reducing blood glucose. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … OZEMPIC 1MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... OZEMPIC 0.25MG, 0.5MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen …
Displaying drugs 1051 - 1075 of 1416 in total