Displaying drugs 10826 - 10850 of 11774 in total
Apaziquone
Apaziquone has been investigated for the treatment of Bladder Cancer and Bladder Neoplasms.
Investigational
Matched Iupac: … 5-(aziridin-1-yl)-3-(hydroxymethyl)-2-[(1E)-3-hydroxyprop-1-en-1-yl]-1-methyl-4,7-dihydro-1H-indole-4,7 …
Sulfamazone
Experimental
Matched Iupac: … (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)({4-[(6-methoxypyridazin-3-yl)sulfamoyl]phenyl …
Telaglenastat
Telaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors).
Investigational
Matched Iupac: … N-[6-(4-{5-[2-(pyridin-2-yl)acetamido]-1,3,4-thiadiazol-2-yl}butyl)pyridazin-3-yl]-2-[3-(trifluoromethoxy …
Epalrestat
Epalrestat is under investigation in clinical trial NCT03244358 (Evaluation of Epalrestat in Metastatic Triple-negative Breast Cancer).
Investigational
Matched Iupac: … 2-[(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic …
CYC-065
CYC-065 is under investigation in clinical trial NCT03739554 (CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory CLL).
Investigational
Matched Iupac: … (2R,3S)-3-[(6-{[(4,6-dimethylpyridin-3-yl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl)amino]pentan-2- …
MK-0668
Experimental
Matched Iupac: … (2S)-2-{[(2S,4R)-1-(3-cyanobenzenesulfonyl)-4-(cyclobutylamino)pyrrolidin-2-yl]formamido}-3-[4-(3,5-dichloropyridine ... -4-amido)phenyl]propanoic acid …
Butropium
Experimental
Matched Iupac: … (1R,3R,5S)-8-[(4-butoxyphenyl)methyl]-3-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-8-methyl-8-azabicyclo …
TERN-101
TERN-101 is under investigation in clinical trial NCT04328077 (LIFT Study: A Safety, Tolerability, Efficacy, and Pharmacokinetics Study of TERN-101 in Subjects With Non-cirrhotic Non-alcoholic Steatohepatitis (NASH)).
Investigational
Matched Iupac: … 6-(4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole ... -3-carboxylic acid …
KW-2450 free base
Experimental
Matched Iupac: … N-(5-{[4-(2-hydroxyacetyl)piperazin-1-yl]methyl}-2-[(1E)-2-(1H-indazol-3-yl)ethenyl]phenyl)-3-methylthiophene …
Henatinib
Henatinib has been used in trials studying the treatment of Advanced Solid Cancer.
Investigational
Matched Iupac: … (3Z)-5-fluoro-3-({5-[(2R)-2-hydroxy-3-(morpholin-4-yl)propyl]-3-methyl-4-oxo-1H,4H,5H,6H,7H,8H-pyrrolo …
CRA_1801
Experimental
Matched Iupac: … 2-(3-hydroxypyridin-2-yl)-1H-1,3-benzodiazole-6-carboximidamide …
Mersalyl
Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
Matched Iupac: … 2-(2-{[3-(hydroxymercurio)-2-methoxypropyl]carbamoyl}phenoxy)acetic acid …
Etymemazine
Experimental
Vet approved
Matched Iupac: … [3-(2-ethyl-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …
Matched Salts cas: … 3737-33-5 …
Matched Salts cas: … 3737-33-5 …
Allicin
Allicin has been used in trials studying the treatment of Follicular Lymphoma.
Investigational
Matched Iupac: … 3-[(prop-2-ene-1-sulfinyl)sulfanyl]prop-1-ene …
Etafenone
Etafenone is a vasodilator.
Experimental
Matched Iupac: … 1-{2-[2-(diethylamino)ethoxy]phenyl}-3-phenylpropan-1-one …
Matched Salts cas: … 2192-21-4 …
Matched Salts cas: … 2192-21-4 …
Cannabivarin
A natural product found in Cannabis sativa.
Experimental
Matched Iupac: … 6,6,9-trimethyl-3-propyl-6H-benzo[c]chromen-1-ol …
Batabulin
Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients).
Investigational
Matched Iupac: … 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzene-1-sulfonamide …
Soticlestat
Investigational
Matched Iupac: … 4-benzyl-1-{[2,4'-bipyridine]-3-carbonyl}piperidin-4-ol …
Nacystelyn
Investigational
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid; (2S)-2,6-diaminohexanoic acid …
Tazobactam trans-enamine intermediate
Experimental
Matched Iupac: … (1S)-1-carboxy-2-methyl-1-{[(1E)-3-oxoprop-1-en-1-yl]amino}-3-(1H-1,2,3-triazol-1-yl)propane-2-sulfonyl …
Tetrodotoxin
An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough pain in advanced cancer patients as...
Investigational
Matched Iupac: … 7,11}.0^{1,6}]tetradec-3-en-4-ium-9-olate ... (11S,13S)-3-amino-5,12,13,14-tetrahydroxy-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1^{ …
Efonidipine
Efonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis...
Experimental
Matched Iupac: … 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ⁵-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl ... )-1,4-dihydropyridine-3-carboxylate …
Verucerfont
Verucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.
Investigational
Matched Iupac: … 3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5 …
Displaying drugs 10826 - 10850 of 11774 in total