Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 1101 - 1125 of 1308 in total

Zalifrelimab

Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Investigational
Matched Synonyms: … A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4) ... Immunoglobulin G1-kappa, anti-(homo sapiens CTLA4 (cytotoxic tlymphocyte-associated protein 4, cd152) …

Etavopivat

Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …

Entecavir

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) in March 2005. ... Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTECAVIR AMAROX 1MG FTA ... ENTECAVIR AMAROX 0.5MG FTA …

Olmesartan

Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding ... , particularly in patients who are unable to tolerate ACE inhibitors. ... In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid …
Matched Mixtures name: … Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil ... Amlodipine and olmesartan Medoxomil …
Matched Categories: … Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... olmesartan medoxomil and diuretics ... olmesartan medoxomil and amlodipine …
Matched Products: … OLMESARTAN AMAROX 10MG FTA ... OLMESARTAN AMAROX 20MG FTA ... OLMESARTAN AMAROX 40MG FTA …

Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen

Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... individually conjugated to diphtheria toxoid protein that are extracted from *Corynebacterium diphtheriae …

Anti-CD7 CAR T-cell therapy

Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …

Cobicistat

Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate …
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate …
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and …
Matched Categories: … darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat …

Doxycycline

Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines. Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and...
Approved
Investigational
Vet approved
Matched Description: … It is also used to treat acne and malaria.[A251730] ... [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections …
Matched Salts name: … Doxycycline calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Vibramycin Calcium …

Recombinant human palmitoyl protein thioesterase-1

Investigational
Matched Name: … Recombinant human palmitoyl protein thioesterase-1 …

A-dmDT390-bisFv(UCHT1)

A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides).
Investigational
Matched Synonyms: … Recombinant anti-cdr-bi-single-chain-fv-diphtheria toxin fusion protein ... Recombinant anti-cdr-bi-single-chain-fv-diptheria toxin fusion protein …
Matched Description: … A-dmDT390-bisFv(UCHT1) is under investigation in clinical trial NCT02943642 (Safety and Effectiveness ... of A-dmdt390-bisfv(ucht1) Fusion Protein in Subjects With Mycosis Fungoides). …

Tranexamic acid

Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Mar-tranexamic Acid ... Tranexamic Acid In Sodium Chloride …

Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 4 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Investigational
Matched Synonyms: … Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... the capsular antigens of *Streptococcus pneumoniae* serotype 4 individually conjugated to the CRM197 protein …

Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 6b individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... the capsular antigens of *Streptococcus pneumoniae* serotype 6b individually conjugated to the CRM197 protein …

Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 1 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... the capsular antigens of *Streptococcus pneumoniae* serotype 1 individually conjugated to the CRM197 protein ... vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein …

Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 5 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... the capsular antigens of *Streptococcus pneumoniae* serotype 5 individually conjugated to the CRM197 protein ... vaccine are prepared from purified polysaccharides that are chemically activated then conjugated to the protein …

Thimerosal

Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Synonyms: … ethyl(2-mercaptobenzoato-S)mercury sodium salt …
Matched Iupac: … sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercury …
Matched Description: … This compound is a well-established and widely used antiseptic and antifungal agent. ... pharmaceuticals, and biological drug products, which includes vaccines. ... Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical …
Matched Categories: … Antiseptics and Disinfectants ... Mercurial Products …

Zinc gluconate

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … of common colds and with decreased symptom severity. ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration ... osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and …
Matched Mixtures name: … Calcium - Magnesium - Zinc Tab ... Calcium Magnesium Avec Vitamine D Et Zinc ... Citrate De Calcium Plus Vitamine D Et Zinc …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Thank you for Last Night …

Paclitaxel

Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … paclitaxel protein-bound particles ... Paclitaxel protein-bound particles for injection suspension …
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar ... Proteins …
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …

5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE

Experimental
Matched Name: … 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE …

Haemophilus influenzae b polysaccharide-tetanus conjugate

Approved
Matched Synonyms: … Haemophilus influenzae type b polysaccharide conjugated to tetanus protein ... Haemophilus influenzae type b polysaccharide conjugated to the tetanus protein …

GALE-302

Investigational
Matched Synonyms: … Folate binding protein J65 …

Eftansomatropin alfa

Eftansomatropin alfa (GX-H9) comprises a recombinant human growth hormone fused to hyFc, a synthetic hybrid Fc fragment. It is under investigation for the treatment of growth hormone deficiency.
Investigational
Matched Synonyms: … Somatotropin (human) fusion protein with immunoglobulin (synthetic hybrid fc fragment hyfc) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Recombinant Proteins …

2',4'-Dinitrophenyl-2deoxy-2-Fluro-B-D-Cellobioside

Experimental
Matched Name: … 2',4'-Dinitrophenyl-2deoxy-2-Fluro-B-D-Cellobioside …

Levofloxacin

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Description: … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Matched Products: … CINA ... PROXAFLO-FLU …

Phenol

Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Description: … Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract. ... Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process ... Phenol is an antiseptic and disinfectant. …
Matched Mixtures name: … Phen-oris - Ont Top ... FUCSINA FENICA MARCO VITI ... Major Camphor and Phenol …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … FENOLO MARCO VITI …
Displaying drugs 1101 - 1125 of 1308 in total