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Displaying drugs 11376 - 11400 of 11997 in total
DYNE-251
DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1). It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping.
Investigational
Matched Description: … It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable …
Oral Polio Vaccine
The oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes. Strains of the virus are selected based on their reduced incidence of spreading to the central nervous system but still having the ability to mimic the immune response that...
Investigational
Matched Description: … in the community to immunize a sizable proportion of those unvaccinated in the population[A220163]. ... After administration, OPV strains extensively multiply in the intestinal tract, becoming widely spread ... The polio vaccine can be either administered in the inactivated form or the oral form, although both …
RO-5028442
RO5028442 has been used in trials studying Autistic Disorder.
Investigational
Matched Description: … RO5028442 has been used in trials studying Autistic Disorder. …
ACT-451840
ACT-451840 has been used in trials studying Malaria.
Investigational
Matched Description: … ACT-451840 has been used in trials studying Malaria. …
PM-060184
PM060184 has been used in trials studying Solid Tumors.
Investigational
Matched Description: … PM060184 has been used in trials studying Solid Tumors. …
AM103
AM103 is a novel inhibitor of 5-lipoxygenase-activiting protein (FLAP) that has demonstrated potential to treat asthma and cardiovascular disease by preventing the synthesis of LT, which triggers inflammation. It is being developed by Amira.
Investigational
Zebularine
A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.
Experimental
Matched Description: … Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. …
Tienilic acid
Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982)
Withdrawn
Matched Description: … It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen …
Palmidrol
A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets).
Experimental
Nutraceutical
Matched Description: … A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory ... Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In …
Pegsitacianine
Pegsitacianine is under investigation in clinical trial NCT05576974 (A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)).
Investigational
Matched Description: … Pegsitacianine is under investigation in clinical trial NCT05576974 (A Phase 2a, Single-dose, Open-label ... Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in …
Flurothyl
Flurothyl is a convulsant primarily used in experimental animals. It was formerly used to induce convulsions as a alternative to electroshock therapy.
Withdrawn
Matched Description: … Flurothyl is a convulsant primarily used in experimental animals. …
Figitumumab
Figitumumab has been used in trials studying the treatment of Sarcoma, Solid Tumor, Breast Cancer, Lung Neoplasms, and Advanced Cancer, among others.
Investigational
Matched Description: … Figitumumab has been used in trials studying the treatment of Sarcoma, Solid Tumor, Breast Cancer, Lung …
Antineoplaston A10
Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
Investigational
Matched Description: … Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, …
Mirogabalin
Mirogabalin has been used in trials studying the treatment of Post-herpetic Neuralgia, Pain Associated With Fibromyalgia, and Diabetic peripheral neuropathic pain.
Investigational
Matched Description: … Mirogabalin has been used in trials studying the treatment of Post-herpetic Neuralgia, Pain Associated …
PF-04457845
PF-04457845 is under investigation in Fear Conditioning. PF-04457845 has been investigated for the treatment of Tourette Syndrome and Cannabis Dependence.
Investigational
Matched Description: … PF-04457845 is under investigation in Fear Conditioning. …
9-aminocamptothecin
Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Investigational
Matched Description: … Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian …
Taladegib
Taladegib has been used in trials studying the treatment of Solid Tumor, COLON CANCER, BREAST CANCER, Advanced Cancer, and Rhabdomyosarcoma, among others.
Investigational
Matched Description: … Taladegib has been used in trials studying the treatment of Solid Tumor, COLON CANCER, BREAST CANCER, …
Fluocinolone
Fluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral Lichen Planus, Macular Degeneration, and Choroidal Neovascularization.
Investigational
Matched Description: … Fluocinolone has been used in trials studying the treatment and prevention of Candida Infection, Oral …
AZD-1480
AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera, Primary Myelofibrosis (PMF), and Essential Thrombocythaemia Myelofibrosis.
Investigational
Matched Description: … AZD1480 has been used in trials studying the treatment of Solid Malignancies, Post-Polycythaemia Vera …
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Description: … Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation …
Beloranib
Beloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma, and Hypothalamic Injury, among others.
Investigational
Matched Description: … Beloranib has been used in trials studying the treatment of Obesity, Over-weight, Type 2 Diabetes, Craniopharyngioma …
Angelica dahurica root
Angelica dahurica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Angelica dahurica root is a plant/plant extract used in some OTC (over-the-counter) products. …
Maclura tricuspidata whole
Maclura tricuspidata whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Maclura tricuspidata whole is a plant/plant extract used in some OTC (over-the-counter) products. …
Juglans regia shell
Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. …
Meadowfoam seed oil
Meadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Meadowfoam seed oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 11376 - 11400 of 11997 in total