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Displaying drugs 1151 - 1175 of 1339 in total
Experimental
Matched Name: … (2s,5s)-5-Carboxymethylproline
Matched Iupac: … (2S,5S)-5-(carboxymethyl)pyrrolidine-2-carboxylic acid …
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for...
Experimental
Illicit
Matched Synonyms: … 3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid ... (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Matched Iupac: … (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Matched Description: … It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. …
Investigational
Matched Synonyms: … -2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperdinyl)phenyl)methyl)-imidazo(1,2-a)pyridine-3-carboxamide ... Imidazo(1,2-a)pyridine-3-carboxamide, 6-chloro-2-ethyl-n-((4-(4-(4-(trifluoromethoxy)phenyl)-1-piperidinyl …
Matched Iupac: … -2-ethyl-N-[(4-{4-[4-(trifluoromethoxy)phenyl]piperidin-1-yl}phenyl)methyl]imidazo[1,2-a]pyridine-3-carboxamide
Investigational
Matched Synonyms: … Uracil-6-carboxylic acid …
Matched Iupac: … 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid …
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and...
Experimental
Investigational
Matched Synonyms: … (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl ... L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycine …
Matched Iupac: … (5S,6R,7E,9E,11Z,14Z)-6-{[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl …
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … 4-(6-methoxy-4-(7-oxo-1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl) ... 4-(6-methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin)-1'-yl)carbonyl
Investigational
Matched Synonyms: … (1,1'-biphenyl)-4-carboxylic acid, 2'-((1r)-1-((2r)-3-((2-(4-chloro-3-fluorophenyl)-1,1-dimethylethyl ... chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3-methyl(1,1'-biphenyl)-4-carboxylic ... chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl)-3-methyl-1,1'-biphenyl-4-carboxylic
Matched Iupac: … chloro-3-fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3-methyl-[1,1'-biphenyl]-4-carboxylic
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Experimental
Matched Synonyms: … (1,10 phenanthroline)-(tri-carbon monoxide) rhenium (I) …
Celivarone is under investigation in clinical trial NCT00233441 (Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 Mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/flutter).
Investigational
Matched Synonyms: … Isopropyl 2-butyl-3-(4-(3-(dibutylamino)propyl)benzoyl)-1-benzofuran-5-carboxylate
Matched Iupac: … propan-2-yl 2-butyl-3-{4-[3-(dibutylamino)propyl]benzoyl}-1-benzofuran-5-carboxylate
Investigational
Matched Synonyms: … 2-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)-1-methyl-1h-pyrrolo(2,3-b)pyridine-3-carboxamide
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
Experimental
Matched Synonyms: … 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper …
Matched Iupac: … lambda1-copper(1+) 4,20-bis(2-carboxyethyl)-10,15-diethyl-5,9,14,19,23-pentamethyl-21,22,23,24-tetraazapentacyclo …
Citarinostat is under investigation in clinical trial NCT02886065 (A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM).
Investigational
Matched Synonyms: … (2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide) …
Experimental
Matched Synonyms: … 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide …
Matched Iupac: … N'-[(E)-(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide
EHT 0202 is developed to treat neurodegenerative disorders by ExonHit Therapeutics.
Investigational
Matched Synonyms: … 1H-PYRAZOLO(3,4-B)PYRIDINE-5-CARBOXYLIC ACID, 1-ETHYL-4-((1-METHYLETHYLIDENE)HYDRAZINO)-, ETHYL ESTER …
Investigational
Matched Synonyms: … (5-(3-(2-amino-4-oxo-4,7-dihydro-3 h-pyrrolo(2,3-d)pyrimidin-6-yl)propyl)thiophene-2-carbonyl)-l-glutamic …
Investigational
Matched Synonyms: … (7h-pyrrolo (2,3-d)pyrimidin-4-yl)amino)-n-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1h-pyrazole-3-carboxamide
Matched Iupac: … {4-[(4-methylpiperazin-1-yl)methyl]phenyl}-4-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-1H-pyrazole-3-carboxamide
PARPI F-18 is a diagnostic agent under investigation for use in the management of glioblastoma multiforme.
Investigational
Matched Synonyms: … 1(2h)-phthalazinone, 4-((4-fluoro-3-((4-(4-(fluoro-18f)benzoyl)-1-piperazinyl)carbonyl)phenyl)methyl) …
Matched Iupac: … 4-[(4-fluoro-3-{4-[4-(18F)fluorobenzoyl]piperazine-1-carbonyl}phenyl)methyl]-1,2-dihydrophthalazin-1- …
Investigational
Matched Synonyms: … Benzamide, n-((1s)-4-(((1r,2s)-2-(4-fluorophenyl)cyclopropyl)amino)-1-((4-methyl-1-piperazinyl)carbonyl ... N-((1s)-4-(((1r,2s)-2-(4-fluorophenyl)cyclopropyl)amino)-1-((4-methyl-1-piperazinyl)carbonyl)butyl)-4 …
Investigational
Matched Synonyms: … 1H-Pyrazole-4-carboxamide, N-[(3-fluoro-4-methoxy-2-pyridinyl)methyl]-3-methoxymethyl)-1-[[4-[(2-oxo- ... methyl]-3-(methoxymethyl)-1-({4-[(2-oxo-1,2-dihydropyridin-1-yl) methyl]phenyl}methyl)-1H-pyrazole-4-carboxamide ... methoxypyridin-2-yl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1(2H)-yl)methyl]phenyl}methyl)-1H-pyrazol-4-carboxamide
Matched Iupac: … methyl]-3-(methoxymethyl)-1-({4-[(2-oxo-1,2-dihydropyridin-1-yl)methyl]phenyl}methyl)-1H-pyrazole-4-carboxamide
Investigational
Matched Synonyms: … Dibenzo(b,f)(1,4)thiazepine-8-carboxamide, 10,11-dihydro-11-oxo-n-((2-(trifluoromethyl)-5-thiazolyl)methyl ... trifluoromethyl)-1,3-thiazol-5-yl)methyl)-10,11-dihydro-5h- 5.lambda.6-dibenzo(b,f)(1,4)thiazepine-8-carboxamide
Pomotrelvir is under investigation in clinical trial NCT05543707 (PBI-0451 (Pomotrelvir) Phase 2 Study in Nonhospitalized Symptomatic Adults With COVID-19).
Investigational
Matched Synonyms: … 1H-Indole-2-carboxamide, 7-chloro-N-[(1S)-2-[[(1S)-1-cyano-2-[(3S)-2-oxo-3-piperidinyl]ethyl]amino]-1 ... {(1S)-1-cyano-2-[(3S)-2-oxopiperidin-3-yl]ethyl}amino)-3- cyclopropyl-1-oxopropan-2-yl]-1H-indole-2-carboxamide
N-(3-carboxypropanoyl)-L-norvaline is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom. This medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase.
Experimental
Matched Name: … N-(3-carboxypropanoyl)-L-norvaline …
Matched Iupac: … (2S)-2-(3-carboxypropanamido)pentanoic acid …
Matched Description: … N-(3-carboxypropanoyl)-L-norvaline is a solid. ... This medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase
Investigational
Matched Synonyms: … (3s)-3-(((1-(2-chlorobenzyl)-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3yl)amino)carbonyl)amino-3-( ... .-((((1-((2-chlorophenyl)methyl)-1,2-dihydro-4-hydroxy-5-methyl-2-oxo-3-pyridinyl)amino)carbonyl)amino …
Matched Iupac: … (3S)-3-[({1-[(2-chlorophenyl)methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino …
Investigational
Matched Synonyms: … 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2 ... -1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro(4.5)decane-3-carboxylate
Matched Iupac: … 1-{5-chloro-[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro[4.5]decane-3-carboxylate
Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.
Experimental
Matched Synonyms: … [(o-carboxyphenyl)thio]ethylmercury …
Matched Iupac: … [(2-carboxyphenyl)sulfanyl](ethyl)mercury …
Displaying drugs 1151 - 1175 of 1339 in total