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Displaying drugs 11876 - 11900 of 14340 in total
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
Experimental
Matched Name: … S-Methyl Thiocysteine Group …
Matched Iupac: … (2R)-2-amino-3-(methyldisulfanyl)propanoic acid …
Investigational
Matched Synonyms: … 4-iodo-3-nitrobenzamide …
Matched Iupac: … 4-iodo-3-nitrobenzamide …
Atrasentan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called endothelin-1 protein receptor antagonists. It is a novel, selective endothelin A receptor antagonist (SERA).
Investigational
Matched Iupac: … (2R,3R,4S)-4-(2H-1,3-benzodioxol-5-yl)-1-[(dibutylcarbamoyl)methyl]-2-(4-methoxyphenyl)pyrrolidine-3- …
Matched Description: … It belongs to the family of drugs called endothelin-1 protein receptor antagonists. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
A non-narcotic oral antitussive agent.
Experimental
Matched Iupac: … 2-[2-(piperidin-1-yl)ethoxy]ethyl 9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(14),3(8),4,6,10,12 ... -hexaene-2-carboxylate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Xanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).
Investigational
Matched Iupac: … (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
MK-886 is an experimental inhibitor of leukotriene synthesis.
Experimental
Matched Iupac: … 3-[3-(tert-butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]
Experimental
Illicit
Esflurbiprofen is under investigation in clinical trial NCT03434197 (Safety and Efficacy of SFPP in Knee Osteoarthritis).
Investigational
Matched Synonyms: … Flurbiprofen, (s)- …
Matched Iupac: … (2S)-2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Capromorelin is under investigation in clinical trial NCT00527046 (Effects Of An Oral Growth Hormone Secretagogue In Older Functionally Limited Adults).
Investigational
Matched Iupac: … N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-2H,3H,3aH,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(benzyloxy ... )-1-oxopropan-2-yl]-2-amino-2-methylpropanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Investigational
Matched Iupac: … ({3-[2-(dimethylamino)ethyl]-1H-indol-4-yl}oxy)phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ro4929097 has been used in trials studying the treatment of Sarcoma, LYMPHOMA, Neoplasms, Wilm's Tumor, and OSTEOSARCOMA, among others.
Investigational
Matched Iupac: … 2,2-dimethyl-N'-[(10S)-9-oxo-8-azatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2,4,6,11,13-hexaen-10-yl]-N- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … 6-chloro-2-cyclohexyl-3-oxo-2,3-dihydro-1H-isoindole-5-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Roquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha.
Investigational
Matched Iupac: … 4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Posiphen is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
Investigational
Matched Iupac: … (3aR,8aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-phenylcarbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … ethyl 4-[2-(piperidin-1-yl)acetamido]benzoate …
Cycloleucine is non-metabolisable amino acid formed by cyclization of leucine. It is also a specific and reversible inhibitor of nucleic acid methylation and widely used in biochemical experiments.
Experimental
Matched Synonyms: … 1-amino-1-cyclopentanecarboxylic acid ... 1-aminocyclopentane-1-carboxylic acid ... 1-aminocyclopentanecarboxylic acid …
Matched Iupac: … 1-aminocyclopentane-1-carboxylic acid …
Although leptin is a circulating signal that reduces appetite, in general, obese people have an unusually high circulating concentration of leptin. These people are said to be resistant to the effects of leptin, in much the same way that people with type 2 diabetes are resistant to the effects of...
Investigational
Matched Description: … people are said to be resistant to the effects of leptin, in much the same way that people with type 2
COVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2. This investigational COVID-19 treatment is currently available through three main pathways: use in registered clinical trials, use through the expanded access COVID-19 protocol (21 CFR...
Investigational
Matched Description: … subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2. …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Gossypol has been used in trials studying the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Iupac: … 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(propan-2-yl)-[2,2'-binaphthalene]-8,8'-dicarbaldehyde …
Experimental
Matched Iupac: … {[(3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
Matched Salts cas: … 81028-91-3
Ingenol disoxate is under investigation in clinical trial NCT02120456 (Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis).
Investigational
Matched Iupac: … (1S,4S,5S,6R,9S,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxotetracyclo[ …
Displaying drugs 11876 - 11900 of 14340 in total