Displaying drugs 1176 - 1200 of 1372 in total
Basic Fibroblast Growth Factor
Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative...
Investigational
Matched Synonyms: … Basic fibroblast growth factor, recombinant human, KCB-1 ... Recombinant human basic fibroblast growth factor, KCB-1 …
Matched Description: … single-chain polypeptide growth factor that plays a significant role in the process of wound healing and ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … single-chain polypeptide growth factor that plays a significant role in the process of wound healing and ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Tisotumab vedotin
Tisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting agent, via a protease-cleavable valine-citrulline linker. Each monoclonal antibody molecule carries an average of four MMAE molecules. Tisotumab vedotin is the first TF-directed ADC...
Approved
Matched Synonyms: … HuMax-TF-ADC …
Matched Description: … vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human ... head and neck cancers. ... tumor-associated angiogenesis, progression, and metastasis for tumor survival. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human ... head and neck cancers. ... tumor-associated angiogenesis, progression, and metastasis for tumor survival. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Reveglucosidase alfa
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER ... FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS …
Dental Mesenchymal Pulp Stem Cells
Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar teeth. Dental pulp stem cells (DPSCs) exhibit fibro-blast like plasticity and adherent properties. They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is...
Investigational
Matched Synonyms: … Allogenic Human Dental Pulp Stem Cells …
Matched Description: … DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity ... DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 ... Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar …
Matched Description: … DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity ... DPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 ... Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar …
TOL-101
Investigational
Matched Synonyms: … Murine IgM monoclonal antibody specific for the human alpha, beta T cell receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
RGX-121
RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the central nervous system.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus (AAV) vector of serotype 9 expressing human iduronate …
Matched Name: … RGX-121 …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …
Matched Name: … RGX-121 …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …
AMT-130
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 5 encoding a microRNA targeted to human Huntingtin gene …
CypCaps
Investigational
Matched Synonyms: … Cytochrome P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric …
Candesartan cilexetil
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … CANDESARTAN PL 1A 8/12.5 ... CANDESARTAN PL 1A 8/12.5 ... CANDESARTAN PL 1A 8/12.5 …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Candesartan 1A Pharma 4 mg - Tabletten ... Candesartan 1A Pharma 8 mg - Tabletten ... Candesartan 1A Pharma 16 mg - Tabletten …
Matched Mixtures name: … CANDESARTAN PL 1A 8/12.5 ... CANDESARTAN PL 1A 8/12.5 ... CANDESARTAN PL 1A 8/12.5 …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … Candesartan 1A Pharma 4 mg - Tabletten ... Candesartan 1A Pharma 8 mg - Tabletten ... Candesartan 1A Pharma 16 mg - Tabletten …
Codeine
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Iupac: … (1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for ... agent, and is also recommended in certain diseases with incessant coughing. ... Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease …
Matched Mixtures name: … ARKODIN SIROP, 125 ML ... NUROFEN PLUS TABLET, 12 ADET ... Acetaminophen and Codeine Phosphate …
Matched Categories: … Cough and Cold Preparations ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... codeine and ibuprofen ... codeine and paracetamol ... Opium Alkaloids and Derivatives …
Matched Products: … CODEIN 1A PHARMA 16MG/ML …
Matched Description: … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for ... agent, and is also recommended in certain diseases with incessant coughing. ... Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease …
Matched Mixtures name: … ARKODIN SIROP, 125 ML ... NUROFEN PLUS TABLET, 12 ADET ... Acetaminophen and Codeine Phosphate …
Matched Categories: … Cough and Cold Preparations ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... codeine and ibuprofen ... codeine and paracetamol ... Opium Alkaloids and Derivatives …
Matched Products: … CODEIN 1A PHARMA 16MG/ML …
Fluvastatin
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Description: … levels and prevent cardiovascular disease. ... Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol ... Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. …
Matched Products: … FLUVASTATIN 1A PH 80MG RET …
Matched Products: … FLUVASTATIN 1A PH 80MG RET …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Recombinant human NAGLU-insulin-like growth factor II ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins …
AGIL-FA
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein …
Pegvorhyaluronidase alfa
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … PEGylated recombinant human hyaluronidase PH20 ... -METHOXY-, AMIDE WITH HYALURONOGLUCOSAMINIDASE (HUMAN ISOENZYME PH20) ... HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And …
Matched Categories: … Enzymes and Coenzymes …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And …
Matched Categories: … Enzymes and Coenzymes …
Obexelimab
Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human CD19 antigen) (human-mus musculus monoclonal XMAB5871 heavy chain), disulfide ... with human-mus musculus monoclonal XMAB5871 light chain, dimer …
Sertraline
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
Several weeks of therapy with sertraline may be required before...
Approved
Matched Description: … (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and ... Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor …
Matched Categories: … Serotonin Agents ... Serotonin Modulators ... Selective Serotonin Reuptake Inhibitors ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … SERTRALIN 1A PHARMA 50MG ... SERTRALIN 1A PHARMA 100MG ... Sertralin 1A Pharma 50 mg - Filmtabletten …
Matched Categories: … Serotonin Agents ... Serotonin Modulators ... Selective Serotonin Reuptake Inhibitors ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … SERTRALIN 1A PHARMA 50MG ... SERTRALIN 1A PHARMA 100MG ... Sertralin 1A Pharma 50 mg - Filmtabletten …
Rozrolimupab
Rozrolimupab is a recombinant polyclonal antibody consisting of 25 different anti-Rhesus D (RhD) antibodies to replace existing anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and the prevention of Hemolytic Disease of Newborns (HDN).
Investigational
Matched Synonyms: … Recombinant human antigen-specific polyclonal antibody (pAb) against RhD antigen expressed in Chinese …
Matched Description: … anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … anti-RhD hyperimmune immunoglobulins for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
AAV-AIPL
AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human AIPL1 gene. Developed by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in AIPL1 gene.
Investigational
Matched Synonyms: … adenovirus associated viral vector serotype 8 containing the human AIPL1 gene …
Matched Description: … AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. …
Matched Description: … AAV-AIPL is an adenovirus-associated viral vector serotype 8 containing the human _AIPL1_ gene. …
PTR-01
Investigational
Matched Synonyms: … Recombinant human collagen alpha-1 (VII) chain homo-trimer (rC7) …
PBFT02
PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein progranulin.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding …
Matched Description: … PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN …
Matched Description: … PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN …
Efungumab
Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment) …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins …
NFS-02
NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene (rAAV2-ND1).
Investigational
Matched Synonyms: … recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene …
Matched Description: … NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized …
Matched Description: … NFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized …
GYM329
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Cyclosporine
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Iupac: … (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28 …
Matched Description: … treat various inflammatory and autoimmune conditions. ... calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and ... [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … CICLOSPORIN 25 1A PHARMA ... CICLOSPORIN 50 1A PHARMA ... CICLOSPORIN 100 1A PHARMA …
Matched Description: … treat various inflammatory and autoimmune conditions. ... calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and ... [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … CICLOSPORIN 25 1A PHARMA ... CICLOSPORIN 50 1A PHARMA ... CICLOSPORIN 100 1A PHARMA …
Displaying drugs 1176 - 1200 of 1372 in total