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Displaying drugs 1176 - 1200 of 1493 in total

Alemtuzumab

Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic ... The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing ... The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … LEMTRADA Concentrate for Solution for Infusion 12 mg ... LEMTRADA CONCENTRATE FOR SOLUTION FOR INFUSION 12 MG/ 1.2 ML …

Paliperidone

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Description: … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic ... Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. ... therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and …
Matched Products: … INVEGA Sustenna Prolonged Release Suspension for IM Injection 25mg/0.25 ml ... INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 ml ... INVEGA Sustenna Prolonged Release Suspension for IM Injection 75mg/0.75ml …

Risankizumab

Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23). It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab...
Approved
Investigational
Matched Description: … It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and ... [A254716] Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease. ... [L39885,L44191,L44231] Risankizumab is being investigated for atopic dermatitis.[A254716] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Skyrizi 75 mg solution for injection in pre-filled syringe ... SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED PEN 150MG/ML ... SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 150MG/ML …

Insulin detemir

Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Description: … 1 and Type 2 Diabetes. ... or fat for storage. ... Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Levemir FlexPen 100U/ML Solution for injection in a prefilled pen ... Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen …

Thiocolchicoside

Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of Superba gloriosa. It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.
Experimental
Matched Description: … It is a muscle relaxant with anti-inflammatory and analgesic effects. ... It has potent convulsant activity and should not be administered to individuals prone to seizures. …
Matched Mixtures name: … TIOMED® FORTE ... TIOMED® FORTE …
Matched Products: … MYAL FORT 8 MG KAPSUL, 10 ADET ... MYAL FORT 8 MG KAPSUL, 14 ADET ... MYAL FORT 8 MG KAPSUL, 20 ADET …

Plantago ovata seed

Approved
Experimental
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … EVAGEL POWDER FOR ORAL SOLUTION 3.5g ... CONSIGEL POWDER FOR ORAL SOLUTION 3.5G …

Plerixafor

Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic stem cell mobilizer.[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune...
Approved
Investigational
Matched Description: … of achieving the optimal CD34+ cell target for tandem transplantation in fewer apheresis procedures. ... Since CXCR4 and SDF-1α are involved in the trafficking and homing of CD34+ cells to the marrow compartment ... [A7115] Plerixafor has orphan drug status in the United States and European Union and was approved …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Mozobil 20 mg/ml solution for injection ... Mozobil Solution for Injection 20mg/ml …

Ranibizumab

Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … , and Health Canada respectively. ... [L41429] It is marketed under the brand names LUCENTIS and SUSVIMO. ... after [bevacizumab], another anti-VEGF anticancer drug, was discovered to inhibit neovascularization and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Lucentis 10mg/ml Solution for Injection ... ACCENTRIX 10MG/ML SOLUTION FOR INJECTION ... LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE …

Belimumab

Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … [A251520] It is currently used to treat SLE and lupus nephritis.[L42630] ... antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and ... [L42630] BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Benlysta Powder for Solution for Infusion 120mg ... Benlysta Powder for Solution for Infusion 400mg …

Pegfilgrastim

Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … pharmacokinetic profile and conditions of use. ... Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF ... [A187601] The drug is approved for use to decrease the incidence of infection, as manifested by febrile …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Pelgraz 6 mg solution for injection in a pre-filled syringe ... Pelgraz Solution for Injection in pre-filled syringe 6mg/0.6mL ... Filpegla 6 mg / 0.6 mL Solution for Injection in Pre-filled Syringe …

Isavuconazonium

Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed by Astellas under the brand Cresemba. It is the prodrug form of isavuconazole, the active moiety, and it...
Approved
Investigational
Matched Description: … [A38834] It is the prodrug form of isavuconazole, the active moiety, and it is available in oral and ... 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis, marketed ... Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July …
Matched Categories: … Isavuconazole and Prodrugs …
Matched Products: … CRESEMBA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200MG …

Lanreotide

Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. Lanreotide is manufactured by the company, Ipsen...
Approved
Matched Description: … Lanreotide is manufactured by the company, _Ipsen Pharmaceuticals_ as lanreotide acetate, and marketed ... It is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. ... Lanreotide was first approved for use in the United States by the FDA on August 30, 2007. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Somatuline Autogel 120mg, prolonged-release solution for injection in a pre-filled syringe ... Somatuline Autogel 60mg, prolonged-release solution for injection in a pre-filled syringe ... Somatuline Autogel 90mg, prolonged-release solution for injection in a pre-filled syringe …

Prilocaine

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Description: … Currently, it is used most often for infiltration anesthesia in dentistry. …
Matched Mixtures name: … Citanest Forte ... Citanest Forte DENTAL ... 4% Citanest Forte Dental With Epinephrine 1:200,000 …
Matched Products: … TAKIPRIL SOLUTION FOR INJECTION 20MG/ML ... Takipril 20mg/ml Solution for Injection …

Cholestyramine

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Categories: … Medications that reduce magnesium levels ... Hypolipidemic Agents Indicated for Hyperlipidemia ... Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia …
Matched Products: … Cholestyramine Powder for Suspension ... Cholestyramine for Oral Suspension ... PHL-cholestyramine Powder for Suspension 400gm/can …

Mitomycin

Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Description: … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations ... , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper Tract …
Matched Categories: … Indicators and Reagents ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITONCO 10mg powder for solution for injection/infusion or intravesical ... Mitomycin for Injection ... Mitomycin for Injection USP …

Obexelimab

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO …

Pentamidine

Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Description: … Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in ... It may cause diabetes mellitus, central nervous system damage, and other toxic effects. …
Matched Categories: … Agents Against Leishmaniasis and Trypanosomiasis ... Antiparasitic Products, Insecticides and Repellents ... Antibiotics for Pneumocystis Pneumonia ... Medications that reduce magnesium levels …
Matched Products: … Pentamidine Isetionate for Injection BP ... DBL™ PENTAMIDINE ISETHIONATE FOR INJECTION BP 300mg ... DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vial …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … used off-label in the outpatient and inpatient setting for atrial fibrillation. ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved ... for its approved indications, according to prescribing information. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Calcium Channel Blockers ... Sodium Channel Blockers ... Potassium Channel Blockers ... Medications that reduce magnesium levels …
Matched Products: … DIOLUX CONCENTRATE FOR SOLUTION FOR INJECTION 50MG/ML ... Amiodarone for Injection 50mg/ml ... Amiodarone Hydrochloride for Injection …

(2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid

Experimental
Matched Name: … (2r)-2-{[Formyl(Hydroxy)Amino]Methyl}Hexanoic Acid …

Gadoteric acid

Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with ... its chelating properties, and gadolinium (Gd3+). ... disruption of the blood-brain barrier (BBB) and/or abnormal vascularity. …
Matched Products: … DOTAGRAF SOLUTION FOR INJECTION 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN VIAL 0.5 MMOL/ML ... CLARISCAN SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MMOL/ML …

Dulaglutide

Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular ... agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …

Peginterferon alfa-2a

Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … 36% for genotype 1 and 59% for genotypes 2-6 after 48 weeks of treatment. ... development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. …
Matched Categories: … Treatments for Hepatitis C ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … PEGASYS PRE-FILLED SYRINGE FOR INJECTION 180 mcg/0.5 ml ... PEGASYS PRE-FILLED SYRINGE FOR INJECTION 135 mcg/0.5 ml …

Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched International brands: … Strifon Forte DSC …
Matched Description: … is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains ... Parafon Forte ... Acetazone Forte …
Matched Categories: … Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …
Matched Products: … Parafon Forte ... Parafon Forte DSC ... PARAFLEX FORTE TABLET 500 MG, 20 ADET …

Flumazenil

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …
Matched Products: … Flumazenil Kabi 0.1 mg/mL Solution for Injection ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 1 MG/10 ML ... FLUMAZENIL-BAXTER SOLUTION FOR INJECTION 0.5 MG/5 ML …

Fosaprepitant

Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment.
Approved
Matched Description: … It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment …
Matched Categories: … Aprepitant and Prodrugs …
Matched Products: … Powder for Solution for Infusion 150mg …
Displaying drugs 1176 - 1200 of 1493 in total