Displaying drugs 12276 - 12300 of 12553 in total
Alovudine F-18
Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).
Investigational
Matched Iupac: … 1-[(2R,4S,5R)-4-(¹⁸F)fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Clorotepine
Experimental
Matched Iupac: … 1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine …
Eritoran
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Matched Iupac: … {[(2R,3R,4R,5S,6R)-4-(decyloxy)-5-hydroxy-6-({[(2R,3R,4R,5S,6R)-4-{[(3R)-3-methoxydecyl]oxy}-6-(methoxymethyl ... )-3-[(11Z)-octadec-11-enamido]-5-(phosphonooxy)oxan-2-yl]oxy}methyl)-3-(3-oxotetradecanamido)oxan-2-yl …
Matched Categories: … Toll-Like Receptor 4, antagonists & inhibitors …
Matched Categories: … Toll-Like Receptor 4, antagonists & inhibitors …
Brigimadlin
Investigational
Matched Iupac: … 7'-tetraene-5'-carboxylic acid ... (3S,10'S,11'S,14'S)-6-chloro-11'-(3-chloro-2-fluorophenyl)-13'-(cyclopropylmethyl)-6'-methyl-2-oxo-1,2 ... -dihydro-8',9',13'-triazaspiro[indole-3,12'-tetracyclo[7.6.0.0^{2,7}.0^{10,14}]pentadecane]-1',3',5', …
Solamargine
Solamargine has been used in trials studying the treatment of Actinic Keratosis.
Investigational
Matched Iupac: … (2S,3R,4R,5R,6S)-2-{[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R ... ]-18-eneoxy]-5-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl]oxy}-6-methyloxane ... ,16S)-5',7,9,13-tetramethyl-5-oxaspiro[pentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-piperidin …
Satoreotide tetraxetan
Investigational
Matched Iupac: … 2-[4-({[(1S)-1-{[(4R,7S,10S,13R,16S,19S)-10-(4-aminobutyl)-4-{[(1R)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl ... -1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2- ... ]carbamoyl}-13-{[4-(carbamoylamino)phenyl]methyl}-16-({4-[(4S)-2,6-dioxo-1,3-diazinane-4-amido]phenyl ... (4-chlorophenyl)ethyl]carbamoyl}methyl)-7,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]acetic …
Satoreotide trizoxetan
Investigational
Matched Iupac: … 4-{[(1S)-1-{[(4R,7S,10S,13R,16S,19S)-10-(4-aminobutyl)-4-{[(1R)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl] ... (4-chlorophenyl)ethyl]carbamoyl}-2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]butanoic acid ... -1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2- ... carbamoyl}-13-{[4-(carbamoylamino)phenyl]methyl}-16-({4-[(4S)-2,6-dioxo-1,3-diazinane-4-amido]phenyl} …
Tylvalosin
Vet approved
Matched Iupac: … (2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy ... (2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo-7- ... }-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate ... (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6R)-6-{[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-4-(acetyloxy)-16-ethyl-15-({[ …
Madecassoside
Experimental
Matched Iupac: … (2S,3R,4S,5S,6R)-6-({[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy ... -6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R …
9-(6-deoxy-alpha-L-talofuranosyl)-6-methylpurine
Experimental
Matched Iupac: … (2R,3S,4R,5R)-2-[(1S)-1-hydroxyethyl]-5-(6-methyl-9H-purin-9-yl)oxolane-3,4-diol …
Huperzine B
Huperzine B is a novel acetylcholinesterase inhibitor.
Investigational
Matched Iupac: … (1R,9R,10R)-16-methyl-6,14-diazatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,16-trien-5-one …
Rimacalib
Rimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).
Investigational
Matched Iupac: … N-{3-[(1S)-1-{2-fluoro-[1,1'-biphenyl]-4-yl}ethyl]-1,2-oxazol-5-yl}morpholine-4-carboximidamide …
MK-7622
MK-7622 has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … 3-[(1S,2S)-2-hydroxycyclohexyl]-6-[(6-methylpyridin-3-yl)methyl]-3H,4H-benzo[h]quinazolin-4-one …
Copper usnate
Experimental
Matched Iupac: … copper(2+) 6,12-diacetyl-1,4-dimethyl-11,13-dioxo-8-oxatricyclo[7.4.0.0^{2,7}]trideca-2,4,6,9-tetraene …
Darglitazone
Experimental
Matched Iupac: … 5-({4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propanoyl]phenyl}methyl)-1,3-thiazolidine-2,4-dione …
Dextrorphan
Experimental
Matched Iupac: … (1S,9S,10S)-17-methyl-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Osoresnontrine
Osoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks in Patients With Schizophrenia on Stable Antipsychotic Treatment.).
Investigational
Matched Iupac: … 1-(oxan-4-yl)-6-[(pyridin-2-yl)methyl]-1H,4H,5H-pyrazolo[3,4-d]pyrimidin-4-one …
N7-Methyl-Formycin A
Experimental
Matched Iupac: … (2R,3S,4R,5S)-2-(hydroxymethyl)-5-[7-(methylamino)-2H-pyrazolo[4,3-d]pyrimidin-3-yl]oxolane-3,4-diol …
Namn
Experimental
Matched Iupac: … 3-carboxy-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1lambda5-pyridin …
Axelopran
Axelopran has been used in trials studying the treatment of OIC and Opioid-induced Constipation.
Investigational
Matched Iupac: … 3-[(1R,3R,5S)-8-{2-[(2S)-N-(cyclohexylmethyl)-2,3-dihydroxypropanamido]ethyl}-8-azabicyclo[3.2.1]octan …
PF-03654764
PF-03654764 has been used in trials studying the basic science and treatment of Allergic Rhinitis.
Investigational
Matched Iupac: … (1r,3r)-3-fluoro-3-{3-fluoro-4-[(pyrrolidin-1-yl)methyl]phenyl}-N-(2-methylpropyl)cyclobutane-1-carboxamide …
Fenoverine
Fenoverine has been used in trials studying the treatment of Irritable Bowel Syndrome.
Investigational
Matched Iupac: … 2-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-1-(10H-phenothiazin-10-yl)ethan-1-one …
GDC-0425
GDC-0425 is under investigation in clinical trial NCT01359696 (A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory Solid Tumors or Lymphoma).
Investigational
Matched Iupac: … 3-[(1-ethylpiperidin-4-yl)oxy]-5,8,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene ... -4-carbonitrile …
MK-0736
MK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)).
Investigational
Matched Iupac: … 3-{4-[3-(ethanesulfonyl)propyl]bicyclo[2.2.2]octan-1-yl}-4-methyl-5-[2-(trifluoromethyl)phenyl]-4H-1,2,4 …
Abscisic Acid
Investigational
Matched Iupac: … (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid …
Displaying drugs 12276 - 12300 of 12553 in total