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Displaying drugs 101 - 125 of 8527 in total
Torasemide
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea ... N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Norgestimate
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Synonyms: … d-13β-Ethyl-17α-ethynyl-17β-acetoxygon-4-en-3-one oxime ... (17α)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime ... (+)-13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one oxime acetate (ester) …
Acetohexamide
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Glimepiride
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … 3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)- …
Matched Mixtures name: … AMARYL®M 4 MG/ 1000 MG ... DUERID 30/4 MG TABLET, 30 ADET ... DUERID 30/4 MG TABLET, 90 ADET …
Matched Products: … SANPRID 4 MG TABLET, 60 ADET ... GLIMAX 1 MG TABLET, 60 ADET ... GLIMAX 2 MG TABLET, 60 ADET …
Matched Mixtures name: … AMARYL®M 4 MG/ 1000 MG ... DUERID 30/4 MG TABLET, 30 ADET ... DUERID 30/4 MG TABLET, 90 ADET …
Matched Products: … SANPRID 4 MG TABLET, 60 ADET ... GLIMAX 1 MG TABLET, 60 ADET ... GLIMAX 2 MG TABLET, 60 ADET …
Procarbazine
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Matched Synonyms: … N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine ... 4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide ... N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide …
Matched Iupac: … 4-[(2-methylhydrazin-1-yl)methyl]-N-(propan-2-yl)benzamide …
Matched Iupac: … 4-[(2-methylhydrazin-1-yl)methyl]-N-(propan-2-yl)benzamide …
Methionine
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid ... (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Salts cas: … 6810-12-4 …
Matched Mixtures name: … NUTRINEAL PD-4 PERITONEAL DIALYSIS SOLUTION WITH 1.1% AMINO ACIDS ... NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Salts cas: … 6810-12-4 …
Matched Mixtures name: … NUTRINEAL PD-4 PERITONEAL DIALYSIS SOLUTION WITH 1.1% AMINO ACIDS ... NUTRINEAL PD]4 Peritoneal Dialysis Solution with 1.1% Amino Acids …
Domperidone
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Synonyms: … 5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone ... 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2 ... 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2 …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 …
Matched Mixtures name: … DEXGARD 30/30 MG MR KAPSUL, 60 ADET ... DUEDOM 60/10 MG KAPSÜL, 30 ADET …
Matched Iupac: … 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3 …
Matched Mixtures name: … DEXGARD 30/30 MG MR KAPSUL, 60 ADET ... DUEDOM 60/10 MG KAPSÜL, 30 ADET …
Osimertinib
Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl …
Matched Iupac: … ,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4- …
Matched Iupac: … ,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4- …
Difenoxin
Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse. Motofen(R)...
Approved
Illicit
Matched Synonyms: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid …
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid …
Matched Description: … Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. …
Matched Salts cas: … 35607-36-4 …
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid …
Matched Description: … Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. …
Matched Salts cas: … 35607-36-4 …
Amiloxate
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Description: … It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. …
Encainide
All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Synonyms: … 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide ... (±)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide ... 4-Methoxy-N-{2-[2-(1-methyl-piperidin-2-yl)-ethyl]-phenyl}-benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Formoterol
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Synonyms: … N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide …
Matched Iupac: … N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide …
Matched Salts cas: … 183814-30-4 …
Matched Mixtures name: … FENOSTER-COMBİ 12MCG-200MCG İNHALASYON İÇİN KAPSÜL, 60+60 ADET ... FENOSTER-COMBİ 12MCG-400MCG İNHALASYON İÇİN KAPSÜL, 60+60 ADET ... FORBUDAY 9+320 MCG INHALASYON ICIN TOZ ICEREN KAPSUL, 60+60 ADET …
Matched Products: … FORADIL 12 MCG INHALER KAPSUL, 60 ADET ... FORAST 12 MCG INHALER SERT KAPSUL, 60 ADET ... VENTOFOR 12 MCG INHALER KAPSUL , 60 KAPSÜL …
Matched Iupac: … N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide …
Matched Salts cas: … 183814-30-4 …
Matched Mixtures name: … FENOSTER-COMBİ 12MCG-200MCG İNHALASYON İÇİN KAPSÜL, 60+60 ADET ... FENOSTER-COMBİ 12MCG-400MCG İNHALASYON İÇİN KAPSÜL, 60+60 ADET ... FORBUDAY 9+320 MCG INHALASYON ICIN TOZ ICEREN KAPSUL, 60+60 ADET …
Matched Products: … FORADIL 12 MCG INHALER KAPSUL, 60 ADET ... FORAST 12 MCG INHALER SERT KAPSUL, 60 ADET ... VENTOFOR 12 MCG INHALER KAPSUL , 60 KAPSÜL …
Nisoldipine
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Synonyms: … isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Dutasteride
Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Synonyms: … (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide ... α,α,α,α',α',α'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidide …
Matched Description: … Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. …
Matched Description: … Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. …
Finasteride
Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Synonyms: … (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide …
Matched Description: … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase …
Matched Description: … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase …
Methylparaben
Methylparaben is used in allergenic testing.
Approved
Matched Synonyms: … Methyl 4-hydroxybenzoate …
Matched Iupac: … methyl 4-hydroxybenzoate …
Matched Iupac: … methyl 4-hydroxybenzoate …
Nilutamide
Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of...
Approved
Investigational
Matched Synonyms: … 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoin …
Matched Iupac: … 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione …
Matched Iupac: … 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione …
Idelalisib
Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab...
Approved
Matched Synonyms: … 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one ... 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one …
Matched Iupac: … 5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one …
Matched Description: … signaling pathways, including B-cell receptor (BCR) signaling and C-X-C chemokine receptors type 5 and type 4 …
Matched Iupac: … 5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one …
Matched Description: … signaling pathways, including B-cell receptor (BCR) signaling and C-X-C chemokine receptors type 5 and type 4 …
Chlorpropamide
Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … N-(4-chlorophenylsulfonyl)-N'-propylurea ... 4-chloro-N-((propylamino)carbonyl)benzenesulfonamide ... 4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Matched Iupac: … 1-(4-chlorobenzenesulfonyl)-3-propylurea …
Tolbutamide
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 3-(p-Tolyl-4-sulfonyl)-1-butylurea ... N-(4-Methylphenylsulfonyl)-N'-butylurea ... N-(4-Methylbenzenesulfonyl)-N'-butylurea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Tolfenamic acid
Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam. In the US, it presents a Status class I by the...
Approved
Investigational
Matched Products: … TOLFEDINE TABLET 60 MG ... TOLCID 4% INJECTION ... TOLFEDINE 4% W/V SOLUTION FOR INJECTION FOR DOGS AND CATS …
Nevirapine
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one …
Matched Products: … VIRAMUNE 200 MG TABLET, 60 ADET …
Matched Products: … VIRAMUNE 200 MG TABLET, 60 ADET …
Azatadine
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaene …
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaene …
N-acetyltyrosine
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Synonyms: … (2s)-2-acetylamino-3-(4-hydroxyphenyl)propanoic acid ... (+)-(2s)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Displaying drugs 101 - 125 of 8527 in total