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Displaying drugs 101 - 125 of 10646 in total
Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Synonyms: … 3-methyl-1-phenyl-5-pyrazolone ... 3-methyl-1-phenylpyrazol-5-one ... 1-phenyl-3-methyl-5-oxo-2-pyrazoline …
Matched Iupac: … 3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Synonyms: … 5-allyl-5-(1-methylbutyl)barbituric acid ... 5-allyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione ... 5-allyl-5-(1-methylbutyl)pyrimidine-2,4,6(1H,3H,5H)-trione …
Matched Iupac: … 5-(pentan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Synonyms: … (1-Amino-3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)propylidene)sulfamide …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Zantac 360 1 per blister 6 blisters ... FAMOC 40 TABLET 40 mg ... FEBCID-40 TABLET 40 mg …
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Synonyms: … 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone …
Matched Iupac: … 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity. It has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. Heme oxygenase 1 is...
Approved
Investigational
Matched Synonyms: … (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate ... 2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold …
Matched Description: … Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. ... Heme oxygenase 1 is an inducible heme-degrading enzyme with anti-inflammatory properties. …
Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such...
Approved
Investigational
Matched Synonyms: … α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile …
Matched Iupac: … 2-[3-(1-cyano-1-methylethyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]phenyl]-2-methylpropanenitrile …
Matched Products: … AROMATT 1 ANASTROZOLE TABLET 1 MG ... ANAST 1 FILM COATED TABLET 1 MG ... AREMED 1
Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. At the moment the primary usage for which isopropyl myristate is formally indicated is as the active...
Approved
Experimental
Matched Synonyms: … 1-Methylethyl tetradecanoate …
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Synonyms: … delta(1)-Hydrocortisone ... delta(1)-Dehydrocortisol ... delta(1)-Dehydrohydrocortisone …
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H, …
Matched Products: … PREDICO-1 ... อาร์พี-โซโลน 1 ... PREDNISOLONE TABLET 1 mg …
Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Withdrawn
Matched Synonyms: … )oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamide ... (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino …
Matched Iupac: … cyclohexyl-2-[(pyrazin-2-yl)formamido]acetamido]-3,3-dimethylbutanoyl]-octahydrocyclopenta[c]pyrrol-1- …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... Telaprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotype 1 [FDA Label] ... Approved in May 2011 by the FDA, Incivek was indicated for the treatment of HCV genotype 1 in combination …
Simvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of Aspergillus terreus. It belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production...
Approved
Matched Synonyms: … dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1- …
Matched Iupac: … 8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1- …
Matched Description: … cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1
Matched Mixtures name: … VYTORIN ® 10/40 MG ... EZIT - ST® 10/40 ... SIMITRI® 145/40 MG …
Matched Products: … SIMLO - 40 SIMVASTATINA 40 MG ... KARDAK 40 FILM-COATED TABLETS 40 MG ... ZENCOR 40
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Synonyms: … 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine ... 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine ... 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine …
Matched Iupac: … 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine …
Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Synonyms: … SF-RI 1
Matched Products: … ALVEOFACT 50 MG/1.2 ML INTRATRAKEAL STERİL APİROJEN SÜSPANSİYON, 1 ADET …
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Mixtures name: … Adapalene 0.3% / Benzoyl Peroxide 2.5% / Clindamycin 1% ... Adapalene 0.1% / Benzoyl Peroxide 2.5% / Clindamycin 1% …
Matched Products: … ACNEFFERİN %0,1 JEL, 1 ADET (30 G) …
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature human tripeptidyl-peptidase 1 ... Immature cell growth-inhibiting gene 1 protein …
Matched Description: … with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase-1
Adrenergic beta-agonist used to control premature labor.
Approved
Investigational
Matched Synonyms: … p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcohol …
Matched Iupac: … 4-[(1S,2R)-1-hydroxy-2-{[2-(4-hydroxyphenyl)ethyl]amino}propyl]phenol …
Matched Products: … PRE-PAR 50 MG/5 ML IM/IV ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …
Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight hydrogenated carbon atoms. It is an inert, slightly amphiphilic compound. Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative.[A259746, A259751] Perfluorohexyloctane...
Approved
Matched Synonyms: … 1-(perfluorohexyl)octane …
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Synonyms: … -7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl …
Matched Iupac: … 7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl- …
Matched Mixtures name: … ENJEKSIYONLUK LIYOFILIZE TOZ IÇEREN FLAKON ,FLAKON, 1 ADET ... ENJEKSIYONLUK LIYOFILIZE TOZ IÇEREN FLAKON ,FLAKON, 1 ADET ... TAZOJECT 2 G/ 0,25G IV ENJEKSIYONLUK LIYOFILIZE TOZ, 1 ADET …
Matched Products: … TAZERACİN 4.5 G IV İNFÜZYON İÇİN LİYOFİLİZE TOZ, 1 ADET ... TAZERACİN 2.25 G IV İNFÜZYON İÇİN LİYOFİLİZE TOZ, 1 ADET ... TAZOCIN EF 2,25 G IV INFUZYON LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Synonyms: … (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide ... (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide …
Matched Iupac: … (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Mixtures name: … SEFBAKTAM 1 GR ENJEKTABL FLAKON, 1 FLAKON + 1 AMPUL ... SULCID IM 1 GR FLAKON, 1 ADET ... SULCID IM/IV 1 GR FLAKON, 1 ADET …
Matched Products: … B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 1 ADET ... BAKSİL 1 G I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 FLAKON ... Combactam 1 g - Trockenstechampullen …
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … MATE 1 Substrates …
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-Phosphoribosyl 1-pyrophosphate ... 5-Phospho-alpha-D-ribose 1-diphosphate ... α-D-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) …
Anileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain. Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by actions in the CNS.
Approved
Illicit
Matched Synonyms: … ethyl 1-(4-aminophenethyl)-4-phenylisonipecotate ... ethyl 1-(p-aminophenethyl)-4-phenylisonipecotate ... ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylate …
Matched Iupac: … ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-acetic acid. The pharmacological effect of indometacin is not fully understood,...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid ... {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid …
Matched Description: … NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- …
Matched Products: … Indocid Sterile Oph Susp 1% ... Mobiflex 1 % Schmerzspray zur Anwendung auf der Haut, Lösung …
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … VEXXON-IGF-1 ... INSULIN-LIKE GROWTH FACTOR 1
Matched Description: … gene for human IGF-1. ... Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1
Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Synonyms: … -1-azabicyclo[3.2.0]heptane-2-carboxylate ... 1'-ethoxycarbonyloxyethyl-(6-D-α-aminophenylacetamido)penicillanate ... 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia …
Matched Iupac: … 1-azabicyclo[3.2.0]heptane-2-carboxylate ... 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia- …
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ... 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Displaying drugs 101 - 125 of 10646 in total