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Displaying drugs 101 - 125 of 12454 in total

Thonzonium

Thonzonium is a monocationic surface-active agent with surfactant and detergent properties. It is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. A common pharmaceutical formulation of thonzonium bromide is...
Approved
Matched Description: … It is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Bempedoic acid

High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are...
Approved
Investigational
Matched Description: … [L12153] About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are insufficiently managed ... High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. ... once a day for reducing LDL cholesterol levels in statin-refractory patients. …

Valproic acid

Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … is the subject of many clinical trials in a variety of cancer types. ... Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in ... [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for …
Matched Mixtures name: … Depakine Chronosphere 50 mg Retardgranulat in Beuteln ... Depakine Chronosphere 50 mg Retardgranulat in Beuteln ... Depakine Chronosphere 250 mg Retardgranulat in Beuteln …
Matched Products: … EPILIM CHRONO 500MG (OBLONG FILM C* ) …

Lithium citrate

Approved

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Description: … ], [A175612] as well as in other formulations to promote and support pregnancy. ... Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity ... Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481 …
Matched Categories: … Fused-Ring Compounds …
Matched Products: … Gesterol In Oil-liq Im 50mg/ml ... Progedex 25 mg Injektionslösung in einer Fertigspritze …

Capsicum oleoresin

Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved
Matched Description: … Capsicum oleoresin is contained in pepper sprays when suspended in water, and acts an active lachrymatory ... Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such ... agent that induces irritation, lacrimation, pain, and temporary blindness when in contact with eyes. …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Products: … C-Lax Laxative ... C Lax Laxative …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Description: … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... Its use has also proven successful in the treatment of HCV in patients co-infected with HIV [A19627]. ... of all genotypes of Hepatitis C with or without cirrhosis. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Treatments for Hepatitis C ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor …

Flurbiprofen

Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Products: … Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Strepsils Honig & Zitrone 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Lemocin Flurbiprofen 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …

Clavulanic acid

Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …

Citric acid

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA...
Approved
Nutraceutical
Vet approved
Matched Description: … A key intermediate in metabolism. It is an acid compound found in citrus fruits. ... Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... [L14120] It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative …
Matched Mixtures name: … A-C-D Solution ... Heparin Sodium In 0.9% Sodium Chloride Injection ... Heparin Sodium In 5% Dextrose Injection, 25000unit/500ml …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Infigratinib

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Description: … By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib ... the treatment of previously treated, unresectable locally advanced or metastatic cholangiocarcinoma in …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Phenoxyethanol

Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Description: … This substance occurs naturally in green tea (EU) [L2621]. ... It is very easy to use in various types of formulations and is chemically stable. ... a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in …

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … [label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate ... degree of cyclooxygenase-2 selectivity (COX-2), nabumetone still produces significant adverse effects in ... with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in …

Elbasvir

Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Description: … [A19626] In a computational target-based drug repurposing investigation published in April 2020, elbasvir ... an infectious liver disease caused by infection with hepatitis C virus (HCV). ... a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …

Fluconazole

Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … It was initially approved by the FDA in 1990. ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. ... Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in …
Matched Products: … Fluconazole in Dextrose ... Fluconazole in Sodium Chloride ... Fluconazole In Sodium Chloride Injection USP …

Indacaterol

Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Description: … It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …

Posaconazole

Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Description: … antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Calcium acetate

The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Categories: … ascorbic acid (vit C) and calcium ... Compounds used in a research, industrial, or household setting …

Sodium citrate

Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Description: … soluble in water, practically insoluble in alcohol. ... It works by neutralizing excess acid in the blood and urine. ... It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely …
Matched Mixtures name: … A-C-D Solution ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Poliovirus type 2 antigen (formaldehyde inactivated)

Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by poliovirus Type 2. The vaccine contains purified and inactivated poliovirus type 2 that were...
Approved
Investigational
Matched Description: … Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization …
Matched Mixtures name: … VeroPol Injektionslösung in einer Fertigspritze ... -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE ... Repevax Injektionssuspension in einer Fertigspritze …

Sucrose

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ombitasvir

Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … an infectious liver disease caused by infection with Hepatitis C Virus (HCV). ... a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, ... Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor …

Azithromycin

Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Description: … It was initially approved by the FDA in 1991 [A174175]. ... -9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring ... In March 2020, a small study was funded by the French government to investigate the treatment of COVID …
Matched Products: … GLED' C ZIT …

Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen

Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Description: … These are heat inactivated and purified. …
Displaying drugs 101 - 125 of 12454 in total