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Displaying drugs 1251 - 1275 of 1674 in total

Sapropterin

Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Description: … phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …
Matched Products: … KUVAN® 100 MG ... KUVAN 100 MG ÇÖZÜNEBİLİR TABLET, 120 ADET ... KUVAN 100 MG ÇÖZÜNEBİLİR TABLET, 240 ADET …

Calendula officinalis flower

Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Calendula X Santamariae Flower …

Ursodeoxycholic acid

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.[A256267,A256463] UDCA was first characterized...
Approved
Investigational
Matched Description: … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by ... [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy ... Cholagogues and Choleretics …
Matched Products: … คอเลแมกซ์ 100 ... URSOCOLIK 250MG KAPSÜL,100 ADET ... URSOMED 300 MG KAPSÜL 100 KAPSÜL …

Zidovudine

A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator...
Approved
Matched Description: … It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves ... Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia …
Matched Mixtures name: … Abacavir Sulfate, Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … zidovudine and lamivudine ... Nucleic Acids, Nucleotides, and Nucleosides ... zidovudine, lamivudine and abacavir ... zidovudine, lamivudine and nevirapine ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … RETROVIR 100 MG KAPSÜL, 100 ADET ... ZIDOMAT 100 (Zidovudine Tablets USP 100mg) ... ZIDOVEX - 100 (Zidovudine capsules USP 100mg) …

Iron sucrose

Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Description: … chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Avofer Injection 100mg/5ml ... Ranofer Injection 100mg/5ml ... VELTIFER 100 MG/5 ML ORAL ÇÖZELTİ, 10 ADET …

Aceclofenac

Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … AINEDIX AC® 100 MG ... AIRTAL FILM COATED TABLETS 100mg ... ACECLOFENACO 100 MG TABLETAS …

Miglustat

Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Description: … patients in the European Union, Brazil, and South Korea. ... Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C ... It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … ZAVESCA® 100 MG ... Miglustat G.L. 100 mg-Hartkapseln ... ZAVESCA 100 MG KAPSUL, 84 ADET …

Temozolomide

Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Synonyms: … (S)-perillyl alcohol temozolomide …
Matched Description: … Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary ... malignant brain tumours with poor prognosis and limited treatment options. ... guanine bases leading to DNA lesions and eventual apoptosis. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … GLIOTEM 100 CAPSULE 100 MG ... TEMOTERO 100 ... โซโลเทม - 100 …

Geraniol

Geraniol is a monoterpene that is found within many essential oils of fruits, vegetables, and herbs including rose oil, citronella, lemongrass, lavender, and other aromatic plants. It is emitted from the flowers of many species of plant and is commonly used by the food, fragrance, and cosmetic industry . Geraniol...
Approved
Experimental
Matched Synonyms: … geranyl alcohol …
Matched Description: … and cosmetic industry[L3333]. ... Geraniol is a monoterpene that is found within many essential oils of fruits, vegetables, and herbs including ... rose oil, citronella, lemongrass, lavender, and other aromatic plants. …

Idarubicin

An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … X 10 MG …

Echinacea angustifolia root

Approved
Experimental
Matched Synonyms: … Echinaceae angustifoliae radix …

Tiapride

Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
Investigational
Matched Description: … Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain. …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Products: … TIAPRID HEXAL 100MG ... TIAPRID STADA 100MG ... TIAPRID 100 1A PHARMA …

Zonisamide

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Sulfur Compounds …
Matched Products: … ZALIPIN 100 MG KAPSÜL ,100 KAPSÜL ... EPİZONYA 100 MG KAPSÜL, 100 ADET ... EXCEGRAN 100 MG KAPSUL, 100 ADET …

Testolactone

An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Approved
Investigational
Matched Synonyms: … 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … XPREZA 100 INJECTION 100 MG/VIAL ... ARGAXIT®100 MG ... NEXTIDINA® 100 MG …

Ceftizoxime

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Description: … of both aerobic and anaerobic gram-positive and gram-negative organisms. ... It has few side effects and is reported to be safe and effective in aged patients and in patients with ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Categories: … Sulfur Compounds …
Matched Products: … CEFIZOX IM LIDOKAINLI 1000 MG FLAKON, 1 ADET …

Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated …
Matched Description: … includes the production of humoral immunity through the development of antibodies (through memory B cells) and ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated …

Pimozide

A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994,...
Approved
Matched Description: … A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol ... for the suppression of vocal and motor tics in patients with Tourette syndrome. …
Matched Products: … NOROFREN 2 MG TABLET, 1000 ADET …

Orphenadrine

A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Approved
Matched Description: … A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm …
Matched Mixtures name: … Orphenadrine Citrate, Aspirin and Caffeine ... Orphenadrine Citrate, Aspirin and Caffeine ... Orphenadrine Citrate, Aspirin and Caffeine …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... orphenadrine (chloride) …
Matched Products: … โอฟี 100 ... โอมิเฟน - 100 ... ออร์ฟีน่า - 100 …

Pinaverium

Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Description: … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility ... disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable ... Pinaverium bromide is the common ingredient in formulations, mostly as oral tablets. …
Matched Mixtures name: … BROMUX D® 100/300 MG CÁPSULA. …
Matched Salts name: … Pinaverium bromide …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents …
Matched Products: … PYNAZER® 100 MG ... BROMUX 100MG TABLETAS. ... DICETEL® TABLETAS 100 MG …

Ferric hydroxide

Experimental
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … NOGİSFER 100MG/5 ML ORAL ÇÖZELTİ, 100 ML ... FERIFER 100 MG/5 ML ORAL COZELTI ICEREN 10 KASIK ... FERIFER 100 MG/5 ML ORAL COZELTI ICEREN 30 KASIK …

Iron polymaltose

Experimental
Matched Mixtures name: … HERREX® FOL 1000 TABLETAS RECUBIERTAS ... FERLOS 100 MG/0.35 MG TABLET, 30 ADET ... SANTAFER FORT 100MG/0,35 MG FILM KAPLI TABLET, 30 ADET …
Matched Products: … DUNOXSOL 100 ... MALTOFER FILM-COATED TABLETS 100MG ... SANTAFER 100MG/2ML AMPUL, 5 ADET …

2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose

Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose …

Propylthiouracil

A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Approved
Investigational
Matched International brands: … Uracil …
Matched Description: … Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine …
Matched Categories: … Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Thyroid Products ... Thyroid Hormone Synthesis Inhibitor ... Thyroid Hormone Synthesis Inhibitors …
Matched Products: … TIROSTAT 100 …

Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hcl and Promethazine Hcl ... Meperidine Hydrochloride and Promethazine Hydrochloride …
Matched Categories: … pethidine and antispasmodics …
Matched Products: … Demerol 100 mg/ml ... DEMOTHINE INJECTION 100MG/2ML ... Demerol 10%-liq Im Sc 100mg/ml …
Displaying drugs 1251 - 1275 of 1674 in total