Displaying drugs 1251 - 1275 of 1625 in total
Dilpacimab
Dilpacimab is under investigation in clinical trial NCT03368859 (A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab).
Investigational
Matched Synonyms: … anti-(notch ligand dll4/vascular endothelial growth factor) (synthetic human pr-1283233 heavy chain), disulfide …
Matched Description: … in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Andecaliximab
Andecaliximab is a monoclonal antibody directed against matrix metallopeptidase 9 (MMP9). Andecaliximab is under investigation in clinical trial NCT03631836 (Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human gelatinase b) (human-mus musculus monoclonal gs-5745 heavy chain), disulfide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … -chain), disulfide with human monoclonal kpl-716 .lambda.-chain, dimer …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Orforglipron
Orforglipron is under investigation in clinical trial NCT06010004 (A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes).
Investigational
Matched Synonyms: … -yl)-2,3-dihydro-2-oxo-1H-imidazol-1-yl]-2,4,6,7-tetrahydro-4-methyl-5H-pyrazolo[4,3-c]pyridin-5-yl]carbonyl ... -yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}carbonyl …
Enalapril
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Synonyms: … 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester …
Matched Description: … fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and ... Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the …
Matched Mixtures name: … CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... enalapril and diuretics ... enalapril and nitrendipine …
Matched Description: … fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and ... Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the …
Matched Mixtures name: … CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG ... CARMEN ACE 10MG/10MG …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... enalapril and diuretics ... enalapril and nitrendipine …
Amoxicillin
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Synonyms: … Amoxicillin anhydrous ... Amoxicillin (anhydrous) …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium ... Amoxicillin and clavulanate potassium …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin …
MB07133
Investigational
Matched Synonyms: … 4-amino-1-(5-o-((2r, 4s)-2-oxido-4-(4-pyridinyl)-1, 3, 2-dioxaphosphorinan-2-yl)-.beta. ... 2(1h)-pyrimidinone, 4-amino-1-(5-o-((2r,4s)-2-oxido-4-(4-pyridinyl)-1,3,2-dioxaphosphorinan-2-yl)-.beta ... 4-Amino-1-[5-O-[(2R, 4S)-2-oxido-4-(4-pyridinyl)-1, 3, 2-dioxaphosphorinan-2-yl]-b-D-arabinofuranosyl …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
PPI-1040
Investigational
Matched Synonyms: … 1-(((z)-hexadec-1-en-1-yl)oxy)-3-((2-oxido-1,3,2-oxazaphospholidin-2-yl)oxy)propan-2-yl (4z,7z,10z,13z ... 4,7,10,13,16,19-docosahexaenoic acid, 2-((1z)-1-hexadecen-1-yloxy)-1-(((2-oxido-1,3,2-oxazaphospholidin …
Enmetazobactam
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Zilovertamab
Investigational
Matched Synonyms: … anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 .gamma.1-chain), disulfide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cagrilintide
Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor).
Investigational
Matched Synonyms: … L-Prolinamide, N-(19-carboxy-1-oxononadecyl)-L-γ-glutamyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-leucyl-L-arginyl-L-histidyl …
Matched Description: … Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With ... Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With ... Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Sevirumab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(CYTOMEGALOVIRUS) (HUMAN MONOCLONAL EV2-7 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Unasnemab
Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury).
Investigational
Matched Synonyms: … g1, anti-(human repulsive guidance molecule rgma) (human-mus musculus clone rh116a3 .gamma.1-chain), disulfide …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Matched Description: … Unasnemab is under investigation in clinical trial NCT04683848 (Study to Assess the Efficacy and Safety …
Galegenimab
Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational
Matched Synonyms: … fragment, anti-(human serine proteinase htra1) (human-mus musculus monoclonal fhtr2163 .gamma.1-chain), disulfide …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Matched Description: … Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and …
Posdinemab
Posdinemab is under investigation in clinical trial NCT04619420 (A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease).
Investigational
Matched Synonyms: … G1, anti-(human phosphorylated tau protein) (human-Mus musculus monoclonal JNJ-63733657 γ1-chain), disulfide …
Livmoniplimab
Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Investigational
Matched Synonyms: … protein garp-transforming growth factor .beta.1 complex) (human monoclonal abbv-151 .gamma.4-chain), disulfide …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
Cefaclor
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Synonyms: … Cefaclor anhydrous …
Matched Categories: … Sulfur Compounds …
Matched Categories: … Sulfur Compounds …
Cantuzumab mertansine
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulfide with human-mouse ... Immunoglobulin g1, anti-(mucin canag) (human-mouse monoclonal c242 heavy chain), disulphide with human-mouse ... Immunoglobulin g1, anti-(mucin canag) human-mouse monoclonal c242 heavy chain), disulfide with human-mouse …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Timolol
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Synonyms: … Timolol anhydrous …
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate …
Matched Categories: … Sulfur Compounds ... Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... timolol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides …
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate …
Matched Categories: … Sulfur Compounds ... Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... timolol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides …
Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Synonyms: … Mercaptopurine anhydrous …
Matched Description: … It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
Matched Description: … It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene
Experimental
Matched Name: … 1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene …
Matched Iupac: … 1-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-(2,4,4-trimethylpentan-2-yl)benzene …
Matched Iupac: … 1-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}-4-(2,4,4-trimethylpentan-2-yl)benzene …
4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL
Experimental
Matched Name: … 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL …
Matched Iupac: … 4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol …
Matched Iupac: … 4-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol …
JQ1
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate ... 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate …
Matched Iupac: … 4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Matched Iupac: … 4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate …
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Displaying drugs 1251 - 1275 of 1625 in total