Displaying drugs 1251 - 1275 of 2550 in total
Podofilox
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Synonyms: … Podophyllinic acid lactone …
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …
Cardiopet
Cardiopet is under investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects).
Investigational
Matched Synonyms: … 2-((1s,2r)-2-(5-(fluoro-18f)tridecyl)cyclopropyl)acetic acid ... Trans-9(rs)-18f-fluoro-3,4(rs,rs)-methyleneheptadecanoic acid ... Cyclopropaneacetic acid, 2-(5-(fluoro-18f)tridecyl)-, (1r,2s)-rel- …
Matched Description: … investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and ... Fatty Acid Uptake in Known or Suspected CAD Subjects). …
Matched Description: … investigation in clinical trial NCT01826773 (Cardiopet as PET Imaging Agent to Assess Myocardial Perfusion and ... Fatty Acid Uptake in Known or Suspected CAD Subjects). …
Calcium Phosphate
Calcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Approved
Matched Synonyms: … Phosphoric acid, calcium salt …
Matched Mixtures name: … Multiple Vitamins and Minerals ... Multiple Vitamins and Minerals ... Multivitamins and Minerals for Men …
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids …
Matched Mixtures name: … Multiple Vitamins and Minerals ... Multiple Vitamins and Minerals ... Multivitamins and Minerals for Men …
Matched Categories: … ascorbic acid (vit C) and calcium ... Alimentary Tract and Metabolism ... Acids ... Acids, Noncarboxylic ... Phosphoric Acids …
Zorubicin
Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Experimental
Matched Synonyms: … Benzoic acid hydrazide, 3-hydrazone with daunorubicin …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Recilisib
Investigational
Matched Synonyms: … 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)benzoic acid ... Benzoic acid, 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)- …
Matched Iupac: … 4-[(1E)-2-[(4-chlorophenyl)methanesulfonyl]ethenyl]benzoic acid …
Matched Iupac: … 4-[(1E)-2-[(4-chlorophenyl)methanesulfonyl]ethenyl]benzoic acid …
D-Leucine
An essential branched-chain amino acid important for hemoglobin formation. [PubChem]
Experimental
Matched Synonyms: … D-2-Amino-4-methylvaleric acid ... (2R)-2-amino-4-methylpentanoic acid …
Matched Iupac: … (2R)-2-amino-4-methylpentanoic acid …
Matched Description: … An essential branched-chain amino acid important for hemoglobin formation. [PubChem] …
Matched Iupac: … (2R)-2-amino-4-methylpentanoic acid …
Matched Description: … An essential branched-chain amino acid important for hemoglobin formation. [PubChem] …
Allysine
Experimental
Matched Synonyms: … 2-Amino-5-formylvaleric acid ... 2-Amino-6-oxo-hexanoic acid …
Matched Iupac: … (2S)-2-amino-6-oxohexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Iupac: … (2S)-2-amino-6-oxohexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Cystine
A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
Approved
Nutraceutical
Matched Synonyms: … L-alpha-Diamino-beta-dithiolactic acid ... (R,R)-3,3'-dithiobis(2-aminopropanoic acid) …
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-2-carboxyethyl]disulfanyl}propanoic acid …
Matched Description: … A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Diamino ... Amino Acids, Sulfur ... Amino Acids, Dicarboxylic …
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-2-carboxyethyl]disulfanyl}propanoic acid …
Matched Description: … A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Diamino ... Amino Acids, Sulfur ... Amino Acids, Dicarboxylic …
Phenobarbital
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Synonyms: … Phenobarbituric Acid ... Phenylethylbarbituric Acid ... 5-Ethyl-5-phenylbarbituric acid …
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents ... A barbituric acid derivative that acts as a nonselective central nervous system depressant. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital With Belladonna Alkaloids …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances ... Excitatory Amino Acid Agents …
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents ... A barbituric acid derivative that acts as a nonselective central nervous system depressant. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital With Belladonna Alkaloids …
Matched Categories: … Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances ... Excitatory Amino Acid Agents …
Farudodstat
Farudodstat (ASLAN003) is under investigation in clinical trial NCT03451084 (A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … 2-(3,5-difluoro-3'-methoxybiphenyl-4-ylamino)nicotinic acid ... 2-((3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino)nicotinic acid ... 2-((3,5-DIFLUORO-3'-METHOXY(1,1'-BIPHENYL)-4-YL)AMINO)-3-PYRIDINECARBOXYLIC ACID …
Matched Iupac: … 2-({3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl}amino)pyridine-3-carboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 2-({3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl}amino)pyridine-3-carboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Omega-6 fatty acids
Omega-6 fatty acids are polyunsaturated fatty acids with a final carbon-carbon double bond in the n-6 position, that is, the sixth bond, counting from the methyl end. They are a family of fatty acid molecules that act as precursors to potent lipid mediator signalling molecules with either pro-inflammatory and anti-inflammatory...
Nutraceutical
Matched Synonyms: … Omega 6 acids ... n-6 fatty acids ... ω-6 fatty acids …
Matched Name: … Omega-6 fatty acids …
Matched Description: … molecules with either pro-inflammatory and anti-inflammatory effects. ... fatty acids. ... Omega-6 fatty acids are polyunsaturated fatty acids with a final carbon-carbon double bond in the n-6 …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Matched Name: … Omega-6 fatty acids …
Matched Description: … molecules with either pro-inflammatory and anti-inflammatory effects. ... fatty acids. ... Omega-6 fatty acids are polyunsaturated fatty acids with a final carbon-carbon double bond in the n-6 …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
Sulfasalazine
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Synonyms: … 5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid ... 5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid ... 5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid …
Matched Iupac: … 2-hydroxy-5-[(E)-2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl]benzoic acid …
Matched Description: … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal ... It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis ... L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Iupac: … 2-hydroxy-5-[(E)-2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl]benzoic acid …
Matched Description: … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal ... It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis ... L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and …
Matched Categories: … Alimentary Tract and Metabolism …
Leucine
An essential branched-chain amino acid important for hemoglobin formation.
Investigational
Nutraceutical
Matched Synonyms: … 2-Amino-4-methylvaleric acid ... (2S)-2-Amino-4-methylpentanoic acid ... (2S)-alpha-2-Amino-4-methylvaleric acid …
Matched Iupac: … (2S)-2-amino-4-methylpentanoic acid …
Matched Description: … An essential branched-chain amino acid important for hemoglobin formation. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain ... Proteinogenic Amino Acids …
Matched Iupac: … (2S)-2-amino-4-methylpentanoic acid …
Matched Description: … An essential branched-chain amino acid important for hemoglobin formation. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Essential ... Amino Acids, Branched-Chain ... Proteinogenic Amino Acids …
Serine
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Investigational
Nutraceutical
Matched Synonyms: … (S)-2-Amino-3-hydroxypropanoic acid ... alpha-Amino-beta-hydroxypropionic acid …
Matched Iupac: … (2S)-2-amino-3-hydroxypropanoic acid …
Matched Description: … It is involved in the biosynthesis of purines; pyrimidines; and other amino acids. ... A non-essential amino acid occurring in natural form as the L-isomer. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Proteinogenic Amino Acids …
Matched Iupac: … (2S)-2-amino-3-hydroxypropanoic acid …
Matched Description: … It is involved in the biosynthesis of purines; pyrimidines; and other amino acids. ... A non-essential amino acid occurring in natural form as the L-isomer. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Amino Acid InJ.W.elecw.25%dex …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Proteinogenic Amino Acids …
Homocysteine
Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.
Experimental
Matched Synonyms: … L-2-amino-4-mercaptobutyric acid …
Matched Iupac: … (2S)-2-amino-4-sulfanylbutanoic acid …
Matched Description: … Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Sulfur …
Matched Iupac: … (2S)-2-amino-4-sulfanylbutanoic acid …
Matched Description: … Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Sulfur …
AGRO100
AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.
Pre-clinical testing demonstrates that...
Investigational
Matched Synonyms: … Nucleic acid aptamer binding to tumor cell nucleon …
Matched Description: … colon cancer, as well as malignant melanoma and leukemia. ... AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear ... Such binding leads to internalization of the complex, and a strong anti-proliferative response in the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … colon cancer, as well as malignant melanoma and leukemia. ... AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear ... Such binding leads to internalization of the complex, and a strong anti-proliferative response in the …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Trofinetide
Trofinetide is a novel synthetic analog of glypromate, also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and the N-terminal tripeptide of insulin-like growth factor 1 (IGF-1). Trofinetide was approved by the FDA on March 10, 2023, for the treatment of Rett syndrome,[L45718,L45748] which is an X-linked...
Approved
Investigational
Matched Synonyms: … glycyl-L-2-methylprolyl-L-glutamic acid …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)-2-methylpyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Description: … glypromate], also known as glycine–proline–glutamate (GPE), a naturally occurring protein in the brain and ... [A258438] Trofinetide is believed to work by reducing inflammation and apoptosis of neurons. ... L45748] which is an X-linked neurodevelopmental disorder characterized by a range of cognitive, motor, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Ammonium lactate
Ammonium lactate is the ammonium salt of lactic acid.
Approved
Matched Synonyms: … Lactic acid ammonium salt …
Matched Description: … Ammonium lactate is the ammonium salt of lactic acid. …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids ... alpha-Hydroxy Acid …
Matched Description: … Ammonium lactate is the ammonium salt of lactic acid. …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids ... alpha-Hydroxy Acid …
Magnesium acetate tetrahydrate
Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical formula of Mg(CH3COO)2 • 4H2O. As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium is an essential element and second...
Approved
Matched Synonyms: … Acetic acid, magnesium salt, tetrahydrate …
Matched Description: … As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms ... maintaining normal cellular function such as production of ATP and efficient enzyme activity. ... Magnesium is an essential element and second most abundant cation in the body that plays a key role in …
Matched Mixtures name: … Plasma-lyte 56 and Dextrose ... Plasma-lyte 56 …
Matched Description: … As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms ... maintaining normal cellular function such as production of ATP and efficient enzyme activity. ... Magnesium is an essential element and second most abundant cation in the body that plays a key role in …
Matched Mixtures name: … Plasma-lyte 56 and Dextrose ... Plasma-lyte 56 …
Ammonium carbonate
Approved
Experimental
Matched Synonyms: … Carbonic acid, diammonium salt …
Matched Categories: … Carbonic Acid …
Matched Categories: … Carbonic Acid …
Psoralen
Investigational
Matched Synonyms: … 6-hydroxy-5-benzofuranacrylic acid .delta.-lactone …
Matched Categories: … Indicators and Reagents …
Matched Categories: … Indicators and Reagents …
Vinylglycine
Vinylglycine is an irreversible inhibitor of aspartate aminotransferase.
Experimental
Matched Synonyms: … (2S)-2-amino-3-butenoic acid …
Matched Iupac: … (2S)-2-aminobut-3-enoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … (2S)-2-aminobut-3-enoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
(2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid
Experimental
Matched Synonyms: … N-Propyl-tartramic acid …
Matched Name: … (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxy-3-(propylcarbamoyl)propanoic acid …
Matched Name: … (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxy-3-(propylcarbamoyl)propanoic acid …
Glypromate
Neuren Pharmaceuticals was developing Glypromate (glycine-proline glutamate), a naturally occurring small-molecule neuroprotectant derived from IGF-1 which inhibits caspase III dependent apoptosis, for the potential treatment of neurodegenerative diseases by IV infusion. In December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
Investigational
Matched Synonyms: … Glycyl-prolyl-glutamic acid …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}pentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 1251 - 1275 of 2550 in total