Displaying drugs 1276 - 1300 of 1780 in total
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … Exa-cel ... Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR …
Matched Description: … Exagamglogene autotemcel is an autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor ... cells which has been investigated in clinical trials for the treatment of severe SCD and severe beta-thalassemia ... progressive multi-organ damage, and premature death. …
Matched Categories: … Blood and Blood Forming Organs ... Autologous Cultured Cell …
Matched Description: … Exagamglogene autotemcel is an autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor ... cells which has been investigated in clinical trials for the treatment of severe SCD and severe beta-thalassemia ... progressive multi-organ damage, and premature death. …
Matched Categories: … Blood and Blood Forming Organs ... Autologous Cultured Cell …
Ongericimab
Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (Hefh).).
Investigational
Matched Synonyms: … ), disulfide with human monoclonal js002 .kappa. ... apoptosis-regulated convertase 1, narc1, narc-1, proprotein convertase 9, pc9)), humanized monoclonal antibody ... Immunoglobulin g4, anti-(neural apoptosis-regulated convertase 1) (human monoclonal js002 .gamma.4-chain …
Matched Description: … Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and …
Matched Description: … Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and …
Recombinant human plasma gelsolin
Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Investigational
Matched Synonyms: … Recombinant human gelsolin …
Matched Name: … Recombinant human plasma gelsolin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins ... Calcium-Binding Proteins ... Intracellular Calcium-Sensing Proteins …
Matched Name: … Recombinant human plasma gelsolin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins ... Calcium-Binding Proteins ... Intracellular Calcium-Sensing Proteins …
Garadacimab
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(human blood-coagulation factor viia) (human monoclonal CSL312 gamma4-chain), ... disulfide with human monoclonal CSL312 lambda-chain, dimer …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and …
Socazolimab
Socazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human programmed death-ligand 1) (human monoclonal zkab001 .gamma.1-chain), ... disulfide with human monoclonal zkab001 .lambda. …
Matched Description: … clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody …
Matched Description: … clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody …
Ginisortamab
Ginisortamab is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors).
Investigational
Matched Synonyms: … Immunoglobulin g4 (232-proline), anti-(human gremlin 1) (human monoclonal ucb6114 .gamma.4-chain), disulfide ... with human monoclonal ucb6114 .kappa. …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and ... Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors …
Matched Description: … is under investigation in clinical trial NCT04393298 (A Study to Assess the Safety, Pharmacokinetics and ... Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors …
Sibeprenlimab
Sibeprenlimab is under investigation in clinical trial NCT05248659 (Phase 2/3 Open-label Trial of Sibeprenlimab in the Treatment of Immunoglobulin a Nephropathy).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human proliferation-inducing ligand protein) (human monoclonal vis649 .gamma ... .2-chain), disulfide with human monoclonal vis649 .kappa. …
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Human endothelin ... Endothelin 1 (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Elotuzumab
Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Synonyms: … Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse …
Matched Description: … onto human IgG1 heavy and kappa light chain frameworks. ... Food and Drug Administration. ... and dexamethasone for the treatment of patients with multiple myeloma who have received one to three …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... SLAMF7-directed Antibody Interactions ... SLAMF7-directed Immunostimulatory Antibody …
Matched Description: … onto human IgG1 heavy and kappa light chain frameworks. ... Food and Drug Administration. ... and dexamethasone for the treatment of patients with multiple myeloma who have received one to three …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... SLAMF7-directed Antibody Interactions ... SLAMF7-directed Immunostimulatory Antibody …
Tarafenacin
Investigational
Matched Synonyms: … (3r)-1-azabicyclo(2.2.2)octan-3-yl (3-fluorophenyl)((3,4,5-trifluorophenyl)methyl)carbamate …
Sage oil
Sage oil is extracted from sage or Salvia officinalis, the herb commonly used for culinary purposes. Salvia officinalis is a common sage and a member of the genus Salvia, that includes aromatic and perennial plants with flowers. Essential oil has been traditionally used in medicine for the relief of pain...
Nutraceutical
Matched Synonyms: … Sage leaf oil ... Sage leaf water ... Salvia officinalis leaf oil …
Matched Description: … *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and ... and infections, as it is reported to exhibit carminative, antispasmodic, antiseptic, and astringent ... , and antibacterial activities [A27252]. …
Matched Description: … *Salvia officinalis* is a common sage and a member of the genus *Salvia*, that includes aromatic and ... and infections, as it is reported to exhibit carminative, antispasmodic, antiseptic, and astringent ... , and antibacterial activities [A27252]. …
Coagulation factor X human
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Synonyms: … Coagulation factor X (human) ... Human coagulation factor X …
Matched Name: … Coagulation factor X human …
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... which contains normally 100 IU/mL of coagulation Factor X derived from healthy donors who have passed viral ... children (aged 12 years and above) with hereditary Factor X deficiency. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Name: … Coagulation factor X human …
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... which contains normally 100 IU/mL of coagulation Factor X derived from healthy donors who have passed viral ... children (aged 12 years and above) with hereditary Factor X deficiency. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Interleukin-15, human recombinant
Investigational
Matched Synonyms: … Human IL-15 …
Matched Name: … Interleukin-15, human recombinant …
Matched Name: … Interleukin-15, human recombinant …
Recombinant soluble human CD4
Investigational
Matched Synonyms: … Recombinant soluble CD4 (human) …
Matched Name: … Recombinant soluble human CD4 …
Matched Name: … Recombinant soluble human CD4 …
Atibuclimab
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE ... IC14, (RECOMBINANT CHIMERIC MAB AGAINST HUMAN CD14) ... WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA. …
Matched Description: … Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe …
Matched Categories: … Amino Acids, Peptides, and Proteins …
anti-OX40 antibody BMS 986178
A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Investigational
Matched Name: … anti-OX40 antibody BMS 986178 …
Matched Description: … A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 ... antibody. …
Matched Description: … A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 ... antibody. …
Mezagitamab
Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia).
Investigational
Matched Synonyms: … Anti-Cd38 monoclonal antibody TAK-079 ... IMMUNOGLOBULIN G1, ANTI-(HUMAN CD38 ANTIGEN) (HUMAN MONOCLONAL AB79 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN …
Matched Description: … Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and …
Matched Description: … Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and …
Rinucumab
Rinucumab is under investigation in clinical trial NCT02418754 (Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-related Macular Degeneration (AMD)).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human platelet-derived growth factor receptor~) (human monoclonal regn2176 heavy ... chain), disulfide with human monoclonal regn2176 k-chain, dimer …
Ad-SGE-REIC
Investigational
Matched Synonyms: … adenovirus vaccine encoding reduced expression in immortalized cell protein …
Anti-CD5 CAR T-cell therapy
Investigational
Matched Synonyms: … anti-CD5 CAR T cells …
Matched Name: … Anti-CD5 CAR T-cell therapy …
Matched Name: … Anti-CD5 CAR T-cell therapy …
Red blood cell-encapsulated L-asparaginase
Red blood cell-encapsulated L-asparaginase is Asparaginase Escherichia coli encapsulated inside donor-derived red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism. It is being investigated in cancers.
Investigational
Matched Synonyms: … L-asparaginase encapsulated in red blood cells …
Matched Name: … Red blood cell-encapsulated L-asparaginase …
Matched Description: … red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism. ... Red blood cell-encapsulated L-asparaginase is [Asparaginase Escherichia coli] encapsulated inside donor-derived …
Matched Categories: … Enzymes and Coenzymes …
Matched Name: … Red blood cell-encapsulated L-asparaginase …
Matched Description: … red blood cells, which target cancer cells capable of altering asparagine and glutamine metabolism. ... Red blood cell-encapsulated L-asparaginase is [Asparaginase Escherichia coli] encapsulated inside donor-derived …
Matched Categories: … Enzymes and Coenzymes …
Calmangafodipir
Investigational
Matched Synonyms: … Calcium,n,n'-1,2-ethanediylbis(n-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycine …
Matched Categories: … Enzymes and Coenzymes …
Matched Categories: … Enzymes and Coenzymes …
Barecetamab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human epidermal growth factor receptor her3) (human monoclonal isu104 .gamma ... .1-chain), disulfide with human monoclonal isu104 .lambda. …
Displaying drugs 1276 - 1300 of 1780 in total