Displaying drugs 13001 - 13025 of 13476 in total
Iclaprim
Investigational
Matched Iupac: … 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine …
Matched Salts cas: … 474793-41-4 …
Matched Salts cas: … 474793-41-4 …
MLN576
XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.
Investigational
Matched Iupac: … N-[(2R)-1-(dimethylamino)propan-2-yl]-1-methoxy-5,10-diazatetraphene-6-carboxamide …
5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile
Experimental
Matched Iupac: … 5-chloro-7-[(propan-2-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile …
6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL
Experimental
Matched Iupac: … 6-benzyl-1-[(benzyloxy)methyl]-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Mepiprazole
Mepiprazole is a minor tranquilizer with a phenylpiperazine structure. It is a pyrazolyl-alkyl-piperazine derivative. Mepiprazole mediates a weak inhibitory action on the uptake of 5-HT on hypothalamic neurons .
Mepiprazole is marketed in Spain for the treatment of anxiety neuroses.
It acts as a 5-HT2A and α1-adrenergic receptor antagonist, and...
Experimental
Matched Iupac: … 1-(3-chlorophenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine …
Matched Salts cas: … 20344-15-4 …
Matched Salts cas: … 20344-15-4 …
Niludipine
Niludipine is a calcium channel blocker.
Experimental
Matched Iupac: … 3,5-bis(2-propoxyethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
UK-396,082
UK-396,082 has been used in trials studying the basic science of Safety, Phase 1, Toleration, Multiple Dose, and Pharmacokinetic.
Investigational
Matched Iupac: … (2S)-5-amino-2-[(1-propyl-1H-imidazol-4-yl)methyl]pentanoic acid …
CP-601927
CP-601,927 has been used in trials studying the basic science and treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … (1S,8R)-4-(trifluoromethyl)-10-azatricyclo[6.3.1.0^{2,7}]dodeca-2(7),3,5-triene …
Pruvanserin
Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders.
Investigational
Matched Iupac: … 7-{4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl}-1H-indole-3-carbonitrile …
Calcium pangamate
Experimental
Matched Iupac: … calcium bis((2R,3S,4R,5R)-6-{[2-(dimethylamino)acetyl]oxy}-2,3,4,5-tetrahydroxyhexanoate) …
Fluanisone
Experimental
Matched Iupac: … 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one …
Fosfructose
Experimental
Matched Iupac: … {[(3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
PF-06459988
PF-06459988 is under investigation in clinical trial NCT02297425 (A Study For Patients With EGFRm (Epidermal Growth Factor Receptor Mutant) Lung Cancer).
Investigational
Matched Iupac: … ]-4-methoxypyrrolidin-1-yl]prop-2-en-1-one ... 1-[(3R,4R)-3-[({5-chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl …
Picrotoxin
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. [PubChem]
Experimental
Matched Iupac: … (1R,3R,5S,8S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.1^{ ... 9,12}.0^{3,5}.0^{5,13}]tetradecane-6,11-dione; (1R,5S,8S,13R,14R)-1-hydroxy-13-methyl-14-(prop-1-en-2- …
Cadazolid
Cadazolid has been used in trials studying the treatment of Clostridium Difficile Infection.
Investigational
Matched Iupac: … 1-cyclopropyl-6-fluoro-7-[4-({2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy}methyl ... )-4-hydroxypiperidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Aurodox
Aurodox is an antibiotic obtained from a streptomyces variant considered as possibly effective against streptococcus pyogenes infections. It may promote growth in poultry.
Experimental
Matched Iupac: … (2S)-N-[(2E,4E,6S,7R)-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-[(1E,3E,5E)-7-(4-hydroxy-1-methyl-2-oxo-1,2-dihydropyridin ... -3-yl)-6-methyl-7-oxohepta-1,3,5-trien-1-yl]oxolan-2-yl]-6-methoxy-5-methylocta-2,4-dien-1-yl]-2-[(2R ... ,3R,4R,6S)-2,3,4-trihydroxy-5,5-dimethyl-6-[(1E,3Z)-penta-1,3-dien-1-yl]oxan-2-yl]butanamide …
Hyperforin
Hyperforin is a phytochemical generated by the plants of the Hypericum family. One of the most important members of this family, due to its medical properties, is Hypericum perforatum, also known as St John's wort.
Nutraceutical
Matched Iupac: … (1R,5S,6R,7S)-4-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)-5-(2-methylpropanoyl …
Cortivazol
Cortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)).
Investigational
Matched Iupac: … [11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4(8),5,9,11-tetraen-17-yl]-2-oxoethyl acetate ... 2-[(1S,2R,13S,14S,16R,17R,18S,20S)-17,20-dihydroxy-2,11,16,18-tetramethyl-7-phenyl-6,7-diazapentacyclo …
Exicorilant
Exicorilant is under investigation in clinical trial NCT03437941 (Study to Evaluate CORT125281 in Combination With Enzalutamide in Patients With Mcrpc).
Investigational
Matched Iupac: … 2-[(4aR,8aS)-1-(4-fluorophenyl)-6-[(2-methyl-2H-1,2,3-triazol-4-yl)sulfonyl]-1H,4H,4aH,5H,6H,7H,8H,8aH ... ,9H-pyrido[3,4-f]indazole-4a-carbonyl]-4-(trifluoromethyl)pyridine …
Bis-Benzamidine
Experimental
Matched Iupac: … 4-{[(1S,3S)-3-[(4-carbamimidoylphenyl)methyl]-2-oxocycloheptyl]methyl}benzene-1-carboximidamide …
8-Methyl-9-Oxoguanine
Experimental
Matched Iupac: … 5-amino-2-methyl-6H,7H-[1,3]oxazolo[5,4-d]pyrimidin-7-one …
Mitoquinone
Mitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to a thousand fold. In 2004, a genomic study of hereditary early-onset Parkinson's disease demonstrated a direct...
Investigational
Matched Iupac: … [10-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl]triphenylphosphanium …
Matched Salts cas: … 845959-50-4 …
Matched Salts cas: … 845959-50-4 …
Pirodavir
Pirodavir is an antipicornavirus agent.
Experimental
Matched Iupac: … ethyl 4-{2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy}benzoate …
Apricoxib
Apricoxib has been used in trials studying the treatment and prevention of Lung Cancer, Breast Cancer, Pancreatic Cancer, Non Small Cell Lung Cancer, and Metastatic Pancreatic Cancer, among others.
Investigational
Matched Iupac: … 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]benzene-1-sulfonamide …
MK-1496
MK-1496 has been used in trials studying the treatment of Neoplasms and Malignant.
Investigational
Matched Iupac: … (1S)-1-{4-[(1S)-1-aminoethyl]phenyl}-2-(tert-butylamino)ethan-1-ol …
Displaying drugs 13001 - 13025 of 13476 in total