Displaying drugs 13876 - 13900 of 14019 in total
MT-0169
MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to a human single chain variable fragment with affinity for human CD38 cell surface protein.
Investigational
Matched Description: … MT-0169 is a usion protein comprised of an enzymatically active Shiga-like toxin-I A1 subunit fused to …
tgAAVCF
tgAAVCF is an adeno-associated virus (AAV) vector encoding the human cystic fibrosis transmembrane conductance regulator protein (CFTR) cDNA. It is being investigated for the treatment of cystic fibrosis.[A259821, A259826]
Investigational
Matched Description: … It is being investigated for the treatment of cystic fibrosis.[A259821, A259826] …
VB10.16
VB10.16 is a novel therapeutic antigen-presenting cell-targeting DNA vaccine developed to treat HPV16-positive cancers. It is composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), a dimerization entity, and the part encoding a protein that specifically binds to antigen-presenting cells (APCs).
Investigational
Matched Description: … It is composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type …
Duvoglustat
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Investigational
Matched Iupac: … (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … Derivatives of deoxynojirimycin may have anti-HIV activity. …
Matched Description: … Derivatives of deoxynojirimycin may have anti-HIV activity. …
Talaporfin
Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.
Investigational
Matched Iupac: … (2S)-2-{2-[(4S,5S)-20-carboxy-4-(2-carboxyethyl)-10-ethenyl-15-ethyl-5,9,14,19-tetramethyl-21,22,23,24 ... tetraazapentacyclo[16.2.1.1^{3,6}.1^{8,11}.1^{13,16}]tetracosa-1,3(24),6,8,10,12,14,16(22),17,19-decaen-2- …
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
Matched Description: … Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia …
OM85
OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.
Investigational
Matched Description: … OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity …
Phorbol 12-myristate 13-acetate diester
Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).
Investigational
Matched Description: … Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs). …
EXOB-001
EXOB-001 consists of extracellular vesicles derived from cultured human umbilical cord mesenchymal stromal cells.
Investigational
Matched Description: … EXOB-001 consists of extracellular vesicles derived from cultured human umbilical cord mesenchymal stromal …
Formononetin
Formononetin is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
Investigational
Matched Description: … Formononetin is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
ARO-ANG3
ARO-ANG3 is a subcutaneously administered RNA interference (RNAi)-based investigational medicine targeting angiopoietin-like protein 3 (ANGPTL3). It was granted an orphan drug designation for the treatment of homozygous familial hypercholesterolemia (HoFH).
Investigational
Matched Description: … It was granted an orphan drug designation for the treatment of homozygous familial hypercholesterolemia …
CER-001
CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies.
Investigational
Matched Description: … [L48290] It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies …
Staurosporine
An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Iupac: … (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28 …
Matched Description: … indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GLPG-1205
GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective and Safe GLPG1205 is for Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Iupac: … 9-(2-cyclopropylethynyl)-2-{[(2S)-1,4-dioxan-2-yl]methoxy}-4H,6H,7H-pyrimido[4,3-a]isoquinolin-4-one …
Matched Description: … GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Nalorphine
Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Experimental
Vet approved
Matched Iupac: … (1S,5R,13R,14S,17R)-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid …
Matched Description: … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid …
Nisoxetine
Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. It was originally investigated as an antidepressant but has no current clinical applications aside from being a research standard SNRI. It has been used to research obesity and energy balance, and exerts some local analgesia effects.
Experimental
Matched Iupac: … [3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine …
Matched Description: … Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. …
Matched Description: … Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. …
1-deoxymannojirimycin
An alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem]
Experimental
Matched Iupac: … (2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem] …
Matched Description: … Derivatives of deoxynojirimycin may have anti-HIV activity. [PubChem] …
Flumequine
Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Withdrawn
Matched Description: … Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Avotermin
Juvista has been investigated for the treatment, prevention, and basic science of Scars, Keloid, and Cicatrix.
Investigational
Matched Description: … Juvista has been investigated for the treatment, prevention, and basic science of Scars, Keloid, and …
Bradykinin
Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl] ... pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-3-phenylpropanamido]-3-hydroxypropanoyl]pyrrolidin ... -2-yl]formamido}-3-phenylpropanamido]-5-carbamimidamidopentanoic acid …
Matched Description: … 2. ... Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type …
Matched Description: … 2. ... Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Description: … Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal …
Aclerastide
Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Investigational
Matched Iupac: … (2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-[(diaminomethylidene ... hexanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2- …
Matched Description: … Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot …
Matched Description: … Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot …
Aminaphthone
Aminaftone has been investigated for the treatment of Cockett Syndrome, May-Thurner Syndrome, and Iliac Vein Obstruction.
Investigational
Matched Iupac: … 1,4-dihydroxy-3-methylnaphthalen-2-yl 4-aminobenzoate …
Matched Description: … Aminaftone has been investigated for the treatment of Cockett Syndrome, May-Thurner Syndrome, and Iliac …
Matched Description: … Aminaftone has been investigated for the treatment of Cockett Syndrome, May-Thurner Syndrome, and Iliac …
MEDI-491
MEDI-491 is a recombinant human parvovirus B19 vaccine composed of the VP1 and VP2 capsid proteins.
Investigational
Matched Description: … MEDI-491 is a recombinant human parvovirus B19 vaccine composed of the VP1 and VP2 capsid proteins. …
BHT-3034
BHT-3034 is a DNA plasmid vaccine immunotherapy under investigation for the treatment of myasthenia gravis.
Investigational
Matched Description: … BHT-3034 is a DNA plasmid vaccine immunotherapy under investigation for the treatment of myasthenia gravis …
RAG-17
RAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase (SOD).
Investigational
Matched Description: … RAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase …
Displaying drugs 13876 - 13900 of 14019 in total