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Displaying drugs 14301 - 14325 of 15271 in total
VTP-194204
Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung Cancer.
Investigational
Matched Description: … Nrx194204 has been used in trials studying the treatment of Parkinson's Disease and Non-small Cell Lung …
2,4-thiazolidinedione
Thiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.
Investigational
Matched Description: … Thiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and …
Tirasemtiv
Tirasemtiv has been used in trials studying the treatment of Myasthenia Gravis, Intermittent Claudication, and Amyotrophic Lateral Sclerosis.
Investigational
Matched Description: … Tirasemtiv has been used in trials studying the treatment of Myasthenia Gravis, Intermittent Claudication, and …
PAC-14028
PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea.
Investigational
Matched Description: … PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and …
Carbendazim
Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Description: … Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor …
Venglustat
Venglustat is under investigation in clinical trial NCT01674036 (Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men).
Investigational
Matched Description: … Venglustat is under investigation in clinical trial NCT01674036 (Safety, Tolerability and Pharmacokinetics …
Ropanicant
Ropanicant is under investigation in clinical trial NCT06126497 (Study Evaluating Safety and Efficacy of Ropanicant in MDD Patients).
Investigational
Matched Description: … Ropanicant is under investigation in clinical trial NCT06126497 (Study Evaluating Safety and Efficacy …
CEP-1347
CEP-1347 is a semi-synthetic compound shown to protect multiple nerve cell types from a variety of insults leading to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and after transplantation.
Investigational
Matched Description: … to programmed cell death (apoptosis) which could improve the survival of dopamine neurons prior to and …
XL820
XL820 is investigated for use/treatment in solid tumors. XL820 is a solid. The proteins that XL820 inhibit include platelet-derived growth factor receptor beta (PDGFR), mast/stem cell growth factor receptor KIT, vascular endothelial growth factor receptor 2, and platelet-derived growth factor receptor alpha, clinically validated targets implicated in a variety of...
Investigational
Matched Description: … (PDGFR), mast/stem cell growth factor receptor KIT, vascular endothelial growth factor receptor 2, and ... XL820 exhibits dose-dependent growth inhibition in models of breast carcinoma, gliomas and leukemia. …
Cirazoline
Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent.
Cirazoline has also been shown to decrease food...
Experimental
Matched Description: … It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. …
H3B-8800
H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting . H3B-8800 was granted orphan drug status by the FDA in August 2017 and...
Investigational
Matched Description: … of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551]. ... H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment …
RDEA806
RDEA806 is a new HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with a high genetic barrier to resistance and a broad spectrum of activity.
Investigational
Matched Description: … HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with a high genetic barrier to resistance and …
SUVN-G3031
SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects).
Investigational
Matched Description: … under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and …
Ansofaxine
Ansofaxine is under investigation in clinical trial NCT02271412 (Multiple Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY03005).
Investigational
Matched Description: … NCT02271412 (Multiple Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability, and …
18-methoxycoronaridine
18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).
Investigational
Matched Description: … investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and …
ABT-288
ABT-288 is under investigation in clinical trial NCT01018875 (Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease).
Investigational
Matched Description: … ABT-288 is under investigation in clinical trial NCT01018875 (Efficacy and Safety Study of ABT-288 in …
Disaccharide tripeptide glycerol dipalmitoyl
Disaccharide tripeptide glycerol dipalmitoyl is under investigation in clinical trial NCT00003667 (Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma).
Investigational
Matched Description: … glycerol dipalmitoyl is under investigation in clinical trial NCT00003667 (Combination Chemotherapy and …
GSK2798745
GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough).
Investigational
Matched Description: … GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness and …
Gavorestat
Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
Investigational
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD …
IP-2018
IP-2018 is under investigation in clinical trial NCT04686916 (Clinical Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients).
Investigational
Matched Description: … IP-2018 is under investigation in clinical trial NCT04686916 (Clinical Trial Studying the Efficacy and …
XL281
XL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway. Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer. XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which...
Investigational
Matched Description: … mutant form of B-RAF, which is activated in 60 percent of melanomas, 24-44 percent of thyroid cancers, and ... activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and …
Oxaprotiline
Oxaprotiline is a norepinephrine reuptake inhibitor of the tetracyclic antidepressant family that is related to maprotiline. This drug was never marketed. Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). Dextroprotiline is the S or dextro isomer of...
Experimental
Matched Description: … Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. ... Both enantiomers have antidepressant effects but levoprotiline also is an antihistamine and dextroprotiline …
LX201
LX201 is a silicone matrix ocular implant that provides sustained release of cyclosporine A (CsA) locally to the eye over the course of one year. LX201 is implanted subconjunctivally (beneath the transparent membrane covering the white of the eye) in a minimally invasive procedure. The implant is being developed clinically...
Investigational
Pumactant
Pumactant is a synthetic surfactant used for treating respiratory distress syndrome in neonates. It is a unique formulation of the naturally occurring phospholipids Dipalmitoylphosphatidycholine (DPPC) and Phosphatidyl Glycerol (PG).
Investigational
Matched Description: … a unique formulation of the naturally occurring phospholipids Dipalmitoylphosphatidycholine (DPPC) and …
Displaying drugs 14301 - 14325 of 15271 in total