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Displaying drugs 126 - 150 of 13781 in total
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Description: … [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component ... of the anchoring fibrils for dermal–epidermal cohesion. ... Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Description: … types of skin cancer called superficial basal cell carcinoma. ... Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. ... Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ALDARA %5 KREM, 6 SAŞE …
Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Description: … then a second phase characterized by various neurological symptoms falling under the categorizations of ... [A237520] Due to a paucity of effective safe and effective acute therapeutic agents, vaccination remains ... recover fully following neurological TBE, neurological sequelae can last for years and rare chronic forms of
Matched Products: … FSME-Immun 0,25 ml Junior Injektionssuspension in einer Fertigspritze ... FSME-Immun 0,5 ml Erwachsene Injektionssuspension in einer Fertigspritze …
Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. Tinzaparin is composed of molecules with and without a special site for high affinity binding...
Approved
Matched Description: … This complex greatly accelerates the inhibition of factor Xa. ... It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. ... Tinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated …
Matched Products: … INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML. ... INNOHEP INYECTABLE VIAL 2 ML. 20.000 UI/ML. ... INNOHEP 10.000 IU/0.5 ML KULLANIMA HAZIR DOLU ENJEKTÖRDE ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 2 ADET …
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … [2-(2-pyridyl)ethyl]methylamine ... 2-[2-(methylamino)ethyl]pyridine ... N-methyl-2-(2-pyridinyl)ethanamine …
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It is currently marketed in Canada by various companies, including Teva Pharmaceuticals. ... 5 years due to a lack of evidence supporting its efficacy. ... [A220333,L16403] Betahistine was first approved by the FDA in the 1970s but withdrawn within approximately …
Matched Products: … HISTIGEN 6 ... เบตาฮีส 6 ... เมอซัน - 6
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Iupac: … 2,6-bis(propan-2-yl)phenol …
Matched Description: … Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory ... using a combination of medications. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia …
Matched Products: … FRESOFOL MCT/LCT EMULSION FOR INJECTION OR INFUSION IN PRE-FILLED SYRINGE 2% ... Propofol "Fresenius" 2 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze ... Propofol "Fresenius" 1 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze …
Iron deficiency is an extremely common condition and is the most frequent cause of anemia worldwide. Iron deficiency results when iron intake, iron stores, and loss of iron from the body do not adequately support production of erythrocytes, also known as red blood cells. Though it is generally considered non...
Approved
Matched Iupac: … -(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}hexane-1,2,3,4,5-pentol ... iron(3+) (2S,3R,4R,5R)-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6
Matched Description: … [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. ... Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January ... that is often administered in iron deficiency, and less likely to cause serious hypersensitivity that …
Matched Products: … Monofer 100 mg/ml solution for injection/infusion in vials ... Monofer 100mg/ml solution for injection/infusion in ampoules …
Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … In particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid ... effect is beneficial for use in inflammatory conditions. ... heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for …
Matched Products: … COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... Taltz 80mg solution for injection in pre-filled pen ... COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET …
Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
Approved
Matched Description: … ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 200MCG/0.3ML ... MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 150MCG/0.3ML ... MIRCERA SOLUTION FOR INJECTION IN PRE FILLED SYRINGE, 100MCG/0.3ML …
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl ... -heptamethyl-1-oxa-6-azacyclopentadecan-15-one ... ]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14 …
Matched Description: … In March 2020, a small study was funded by the French government to investigate the treatment of COVID ... It was initially approved by the FDA in 1991 [A174175]. ... The results were positive, all patients taking the combination were virologically cured within 6 days …
Matched Products: … ZITROTEK FILM KAPLI TABLET, 2 ADET ... AZİTROTEK 500 MG FİLM TABLET, 2 TABLET ... TREMAC 250 MG KAPSÜL, 6 KAPSÜL …
Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition but is more commonly used in veterinary medicine. Radiolabelled compound, DB09293, is used as a diagnostic tool to evaluate thyroid function...
Approved
Matched Description: … [L2065] but is more commonly used in veterinary medicine. ... Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition …
Matched Mixtures name: … De La Cruz Tincture of Iodine ... GNP Idoinde Tincture 2% Mild ... LEADER 2% Mild Iodine Tincture …
Certolizumab pegol is a pegylated monoclonal antibody against the tumor necrosis factor-alpha (TNF-alpha). It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. The absence of the Fc region was ideated...
Approved
Matched Description: … [A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 ... The absence of the Fc region was ideated to prevent complement fixation and antibody-mediated cytotoxicity ... [A176606] It was developed and manufactured by UCB Pharma, first FDA approved in 2008[L45018] and updated …
Matched Products: … CIMZIA 200 MG/ML SC STERIL KULLANIMA HAZIR 2 ENJEKTOR ... CIMZIA 200 MG ILO IN FER ... CIMZIA 200MG ILO IN FER …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … [L11812] PEG 3350 is also used for cleansing of the colon in preparation for colonoscopy in adults. ... [L6421] The rationale of using PEG in gastroenterology is due to the physical properties of the compound ... [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Mix-In Laxative Packets …
Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .
Approved
Matched Iupac: … 4-[(1R)-1-hydroxy-2-{[4-(4-hydroxyphenyl)butyl]amino}ethyl]benzene-1,2-diol …
Matched Description: … order to aid in diagnosing the presence or absence of coronary artery disease in patients who cannot ... system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Compounds used in a research, industrial, or household setting …
Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation . In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in...
Approved
Investigational
Matched Description: … Developed by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the ... manifestations of psoriasis. ... In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in dermatological …
Matched Products: … TREMFYA 100 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/1ML …
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic conjunctivitis.[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first...
Approved
Matched Synonyms: … 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone …
Matched Iupac: … 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one …
Matched Description: … allergic rhinitis in patients 6 years of age and older. ... between enantiomers, and was first granted FDA approval in 1996. ... [L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity …
Matched Products: … ZELASS-M % 0.05 GÖZ DAMLASI,6 ML ... ALLERGODİL %0,05 GÖZ DAMLASI, ÇÖZELTİ, 6 ML …
Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Synonyms: … gadolinium(III) 2,2',2''-(10-((2R,3S )-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7 …
Matched Iupac: … 4,7,10-tris(carboxymethyl)-1-[(2S,3R)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetraaza-13-gadolinatetracyclo …
Matched Description: … magnetic resonance imaging (MRI) in adults and children older than 2 years of age. ... a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in ... of NSF thanks to the macrocyclic structures that limit dechelation of gadolinium. …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Products: … Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen ... Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/Patronen …
Approved
Matched Products: … NeisVac-C Injektionssuspension in einer Fertigspritze …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … and higher risk of osteoporosis in long term use. ... UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular ... Furthermore, the effects of UH can typically be reversed by using protamine sulfate. …
Matched Salts cas: … 37270-89-6
Matched Mixtures name: … Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose …
Matched Products: … Heparin Sodium in Dextrose ... Heparin Sodium in Sodium Chloride ... Heparin Sodium In Sodium Chloride …
First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive...
Approved
Matched Iupac: … 3-ethyl-4-methyl-2-oxo-N-(2-{4-[({[(1r,4r)-4-methylcyclohexyl]carbamoyl}amino)sulfonyl]phenyl}ethyl)- …
Matched Description: … Sulfonylureas are one of the insulin secretagogues widely used for the management of type 2 diabetes ... used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control. ... First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class …
Matched Mixtures name: … GLUCOVEL 2 ... LAPIGIM 2/500 ... VELACOM PLUS 2/500 …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … Amaryl 6 mg Tabletten ... AMARYL 6 MG TABLET, 30 ADET ... AMARYL 6 MG TABLET, 90 ADET …
Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Description: … [A203111] Pamidronic acid was first described in the literature in 1977. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … Pamidronate Disodium Omega 6 mg/ml ... Pamidronat Dinatrium Pfizer 6 mg/ml, Konzentrat zur Herstellung einer Infusionslösung …
Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Description: … It is typically used in the management of asthma, cardiac dyspnea, and bronchitis. …
Matched Categories: … combinations of xanthines ... Heterocyclic Compounds, 2-Ring …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 6 AMPUL …
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … 2-(5-Benzyl-2-thienyl)propionsäure ... 2-(5-Benzoyl-thiophen-2-yl)-propionic acid ... 5-benzoyl-α-methyl-2-thiopheneacetic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Description: … Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly ... It belongs to the _arylpropionic acid_ (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … SURGAM 300 MG SUPOZITUVAR, 6 ADET …
Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm infections including ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis . Pyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use...
Approved
Vet approved
Matched Iupac: … 1-methyl-2-[(E)-2-(thiophen-2-yl)ethenyl]-1,4,5,6-tetrahydropyrimidine …
Matched Description: … spastic paralysis of susceptible nematodes (worms). ... Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm ... pharmacokinetic properties (specifically, duration of action) for use as an anthelmintic drug. …
Matched Salts cas: … 22204-24-6
Matched Products: … ASKOL ÇIĞNEME TABLETI, 6 ADET ... KONTIL 250 MG ÇİĞNEME TABLETİ, 6 ADET …
Displaying drugs 126 - 150 of 13781 in total