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Displaying drugs 126 - 150 of 14379 in total

Sulfadimethoxine

Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Description: … Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully ... Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and …
Matched Mixtures name: … TP-SULTRIME 80/400MG/G POWDER …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Metronidazole

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … It is available in capsule form, tablet form, and topical form, and suppository preparations for the ... , and amebiasis which are parasitic infections. ... [L3754] It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metronidazole and diloxanide ... spiramycin and metronidazole ... cefuroxime and metronidazole ... norfloxacin and metronidazole …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …

Telavancin

Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Approved
Matched Description: … skin and subcutaneous tissue infections among others. ... vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and ... pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Iopodic acid

Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Description: … It was developed and filed to the FDA by the company BRACCO. ... formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and ... [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque …

Secretin human

Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Description: … of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification ... Secretin is also responsible in body fluid homeostasis [A32276] and bile production. ... secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Lumefantrine

Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Description: … and may be used to treat infections caused by P. falciparum and unidentified Plasmodium …
Matched Mixtures name: … LUTER TABLET 80/480MG …
Matched Categories: … artemether and lumefantrine ... Antiparasitic Products, Insecticides and Repellents …

Colistin

Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.
Approved
Matched Description: … It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Colistimethate

Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Categories: … Amino Acids, Peptides, and Proteins …

Cefepime

Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Description: … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against ... [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused ... by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical …
Matched Categories: … cefepime and amikacin …
Matched Products: … Cefepime Hydrochloride and Dextrose …

Ondansetron

A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Description: … cisplatin, and has reported anxiolytic and neuroleptic properties. ... Commonly formulated as oral tablets, orally disintegrating tablets (ODT), and injections, and available ... ondansetron has demonstrated a long history of use and efficacy. …
Matched Categories: … Antiemetics and Antinauseants …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …

Bazedoxifene

Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Description: … It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. ... In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the …
Matched Categories: … Genito Urinary System and Sex Hormones ... conjugated estrogens and bazedoxifene ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Mepolizumab

Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote ... Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically ... spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Lamivudine

A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … lamivudine and abacavir ... stavudine and lamivudine ... zidovudine and lamivudine ... lamivudine and raltegravir ... lamivudine and dolutegravir …
Matched Products: … Lamivudine and Zidovudine …

Insulin detemir

Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Description: … tissues such as the liver, fat cells, and skeletal muscle. ... inhibits lipolysis and proteolysis among many other functions. ... The myristoyl side chain increases self-association and albumin binding. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Nalidixic acid

Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational

Sufentanil

Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes. Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Description: … It is administered by the intravenous, epidural and sublingual routes. ... Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and ... analgesic in certified medically supervised healthcare settings, including hospitals, surgical centers, and …
Matched Categories: … Fentanyl and fentanyl analogues …

Eucalyptus oil

Eucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions....
Approved
Matched Description: … membranes, joint pain, genital herpes, and nasal stuffiness. ... It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on ... Eucalyptus oil can be applied directly to the skin for pain and swelling of respiratory tract mucous …
Matched Mixtures name: … Muscle and Joint Heat Cream ... Chest Rub and Cough Suppressant ... Muscle and Joint Pain Relief Gel …
Matched Categories: … Other Cold and Cough Preparations …

Pegaspargase

Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia. Asparagine is an amino acid that is vital for cell survival. In humans, most normal tissues can produce asparagine through the action of asparagine synthetase. However, leukemia...
Approved
Investigational
Matched Description: … Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine ... reducing immune detection, and it also increases the half-life of L-asparaginase. ... However, leukemia cells have low levels of this enzyme and depend on exogenous sources. …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …

Ubidecarenone

Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is...
Approved
Investigational
Nutraceutical
Matched Description: … From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number ... [A7874] It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative ... [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant …
Matched Mixtures name: … Vitamin E and Coq10 ... Co-q10 and Vitamin E ... Co-q10 M.R.B. 100mg and Vitamin E …
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition …
Matched Products: … Coenzyme Q10 With Hawthorn Extract and Citrus Bioflavonoids …

Desogestrel

Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Description: … family which was largely used in Europe before being approved in the US and Canada. ... Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane ... [A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent …
Matched Mixtures name: … Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol …
Matched Categories: … desogestrel and estrogen ... desogestrel and ethinylestradiol ... desogestrel and ethinylestradiol ... Genito Urinary System and Sex Hormones ... Combination Contraceptives (with Estrogen and derivatives) …

Glasdegib

Glasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group of benzimidazoles. In early research, benzimidazoles attracted large interest as they represented a class of inhibitors with low molecular weight, potent inhibitory activity, and lacking unstable functionality. The great lipophilicity of this group of compounds...
Approved
Investigational
Matched Description: … [A40310] Glasdegib was developed by Pfizer Inc and approved on November 21, 2018 by the FDA for the ... interest as they represented a class of inhibitors with low molecular weight, potent inhibitory activity, and ... monotherapy is limited, the landmark Phase 2 Bright AML 1003 trial showed a superior overall survival and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Aliskiren

Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Description: … [A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. ... Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension …
Matched Categories: … valsartan and aliskiren ... aliskiren and amlodipine ... aliskiren and hydrochlorothiazide ... aliskiren, amlodipine and hydrochlorothiazide …

Capivasertib

Hormone receptor (HR) positive, especially estrogen receptor-positive, HER2-negative breast cancer is the most common subtype of metastatic breast cancer, resulting in more than 400,000 deaths annually. Although endocrine-based therapy is the first line of treatment, resistance eventually emerges, leaving chemotherapy the only but often ineffective treatment left. Therefore, significant research...
Approved
Investigational
Matched Description: … based on favorable results obtained from the CAPItello-291 trial, where the combination of capivasertib and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Icosapent

Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Matched Description: … It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. ... inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families. ... lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and …
Matched Mixtures name: … GYNOTARDYFERON 80 MG/0,35 MG UZATILMIŞ SALIMLI KAPLI TABLET, 30 ADET …
Displaying drugs 126 - 150 of 14379 in total