Displaying drugs 1501 - 1525 of 7374 in total
Flumazenil
Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Iupac: … ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene- ... 5-carboxylate …
Matched Products: … ANTİZEPİN 1 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET …
Matched Products: … ANTİZEPİN 1 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET …
Uridine triacetate
Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Synonyms: … 2',3',5'-Triacetyluridine ... 2',3',5'-tri-O-acetyluridine ... Uridine 2',3',5'-triacetate …
Matched Iupac: … [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl acetate …
Matched Description: … It is provided in the prodrug form as uridine triacetate as this form delivers 4- to 6-fold more uridine ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). ... fluorouracil (5-FU) metabolites for incorporation into the genetic material of non-cancerous cells. …
Matched Iupac: … [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl acetate …
Matched Description: … It is provided in the prodrug form as uridine triacetate as this form delivers 4- to 6-fold more uridine ... -5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). ... fluorouracil (5-FU) metabolites for incorporation into the genetic material of non-cancerous cells. …
Avobenzone
Avobenzone is dibenzoyl methane derivative. It is oil soluble ingredient. Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. Avobenzone is very sensitive to light, to increase its stability and duration...
Approved
Investigational
Matched Iupac: … 1-(4-tert-butylphenyl)-3-(4-methoxyphenyl)propane-1,3-dione …
Matched Mixtures name: … Avobenzone 3% Homosalate 10% Octisalate 5% Octocrylene 10% ... No-AD Spf30 5 Oz ... Soleil Ambre SPF 5 …
Matched Mixtures name: … Avobenzone 3% Homosalate 10% Octisalate 5% Octocrylene 10% ... No-AD Spf30 5 Oz ... Soleil Ambre SPF 5 …
Diethylstilbestrol
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Synonyms: … (E)-3,4-bis(4-hydroxyphenyl)-3-hexene …
Matched Iupac: … 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol …
Matched Iupac: … 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol …
Ornithine
Produced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Approved
Nutraceutical
Matched Salts cas: … 5191-97-9 …
Matched Mixtures name: … AMINOPLASMAL-5% E INFUSION ... Primene 10% ... Primene 10%-liq IV …
Matched Products: … HEPA-ORNITAT 5 G/10 ML INFÜZYON KONSANTRESI, 10 ADET ... Hepa-Merz 5 g / 10 ml Infusionslösungs-Konzentrat ... HEPALORNİTİN 5 G / 10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 10 ADET …
Matched Mixtures name: … AMINOPLASMAL-5% E INFUSION ... Primene 10% ... Primene 10%-liq IV …
Matched Products: … HEPA-ORNITAT 5 G/10 ML INFÜZYON KONSANTRESI, 10 ADET ... Hepa-Merz 5 g / 10 ml Infusionslösungs-Konzentrat ... HEPALORNİTİN 5 G / 10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 10 ADET …
Human papillomavirus type 52 L1 capsid protein antigen
Human papillomavirus type 52L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 52 The vaccine is prepared from the purified virus-like...
Approved
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Matched Mixtures name: … Gardasil 9 ... Gardasil 9 ... Gardasil 9 …
Prasterone
Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion.
In...
Approved
Investigational
Nutraceutical
Matched Synonyms: … 3β-hydroxyandrost-5-en-17-one ... 3-beta-hydroxy-5-androsten-17-one ... 3beta-hydroxyandrost-5-en-17-one …
Testosterone
Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995]
Testosterone was isolated from samples and also synthesized in 1935.
Approved
Investigational
Matched Synonyms: … 4-androsten-17β-ol-3-one ... 17beta-hydroxy-4-androsten-3-one …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …
Zinc acetate
Approved
Investigational
Delamanid
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Synonyms: … (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo ... (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo ... Imidazo(2,1-B)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … Spontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … Spontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 …
Ampicillin
Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- …
Matched Mixtures name: … BACTAMED 500 MG/250 MG IM IV ENJEKTABL TOZ IÇEREN FLAKON, 10 ADET ... BACTAMED 1000MG/500MG IM IV ENSEKSIYONLUK TOZ IÇEREN FLAKON ,10 FLAKON …
Matched Products: … PENORAL SÜSPANSİYON, 8 ML ... AMPISINA 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 10 ADET ... AMPİSİNA 500 MG IM/IV ENJEKTABL TOZ İÇEREN FLAKON, 10 ADET …
Matched Mixtures name: … BACTAMED 500 MG/250 MG IM IV ENJEKTABL TOZ IÇEREN FLAKON, 10 ADET ... BACTAMED 1000MG/500MG IM IV ENSEKSIYONLUK TOZ IÇEREN FLAKON ,10 FLAKON …
Matched Products: … PENORAL SÜSPANSİYON, 8 ML ... AMPISINA 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 10 ADET ... AMPİSİNA 500 MG IM/IV ENJEKTABL TOZ İÇEREN FLAKON, 10 ADET …
Orlistat
The global prevalence of obesity is increasing rapidly. Obesity-related complications lead to significant personal and economic burden by reducing quality of life and increasing the cost of healthcare. In some individuals, diet and exercise are insufficient to maintain weight loss, and pharmacological or surgical intervention is required. Orlistat is a...
Approved
Investigational
Matched Iupac: … (2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate …
Pimavanserin
Pimavanserin is an atypical antipsychotic indicated for the treatment of psychiatric disorders. Although the exact mechanism of action is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5-HT2A and HT2C receptors. Unlike other atypical antipsychotics, pimavanserin lacks inherent dopaminergic activity. In fact, pimavanserin is the...
Approved
Investigational
Matched Iupac: … 1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-{[4-(2-methylpropoxy)phenyl]methyl}urea …
Matched Description: … is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5- …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Matched Description: … is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5- …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Isoeugenol
Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by...
Approved
Experimental
Matched Synonyms: … 4-Propenylguaiacol ... 2-Methoxy-4-propenylphenol ... 2-methoxy-4-(prop-1-en-1-yl)phenol …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Anifrolumab
Anifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus.[A237074,L34929] The standard therapy for systemic lupus erythematosus consists of antimalarials like hydroxychloroquine, glucocorticoids like dexamethasone, and disease modifying antirheumatic drugs like methotrexate.[A237079,L34929]
Three...
Approved
Investigational
Azilsartan medoxomil
Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor blocking (ARB) drug class. It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011. Many guidelines...
Approved
Investigational
Matched Iupac: … (5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1 ... '-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylate …
Vedolizumab
Vedolizumab is a recombinant humanized IgG1 monoclonal antibody directed against the human lymphocyte α4β7 integrin, a key mediator of gastrointestinal inflammation implicated in diseases like ulcerative colitis or Crohn's disease. α4β7 integrin facilitates the interaction between lymphocytes and gut endothelial cells through the α4β7 integrin-MAdCAM1 interaction, leading to the mobilization...
Approved
Matched Description: … a period of 30 minutes; after the first dose, it is given again at two and six weeks and then every 8 …
Metacycline
A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Synonyms: … 6-Methylene-5-oxytetracycline ... 6-Methylene-5-hydroxytetracycline ... 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline …
Matched Iupac: … (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a …
Matched Salts cas: … 3963-95-9 …
Matched Iupac: … (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a …
Matched Salts cas: … 3963-95-9 …
Rilpivirine
Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine derivative. The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance...
Approved
Matched Synonyms: … 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Matched Iupac: … 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Matched Iupac: … 4-{[4-({4-[(1E)-2-cyanoeth-1-en-1-yl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile …
Berberine
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Approved
Investigational
Matched Iupac: … 16,17-dimethoxy-5,7-dioxa-13lambda5-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2,4(8) …
Matched Salts cas: … 633-65-8 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Salts cas: … 633-65-8 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Hexylresorcinol
Hexylresorcinol is a substituted dihydroxybenzene. It exhibits antiseptic, anthelmintic, and local anesthetic properties. It can be found in topical applications for minor skin infections and in oral solutions or throat lozenges for pain relief and first aid antiseptic.
The compound may also be used commonly in various commercial cosmetic anti-aging...
Approved
Matched Synonyms: … 4-hexylresorcinol ... 4-hexyl-1,3-benzenediol …
Matched Iupac: … 4-hexylbenzene-1,3-diol …
Matched Iupac: … 4-hexylbenzene-1,3-diol …
Levodopa
Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent...
Approved
Matched Mixtures name: … Sinemet 100/10 ... Pro-lecarb-100/10 - Tab ... DUODOPA 20 MG/ML + 5 MG/ML INTESTINAL JEL, 7 ADET …
Sodium feredetate
Approved
Matched Iupac: … }.0^{1,8}]tetradecan-5-ium-8-ylium-1,1-diuide ... sodium 5-(carboxymethyl)-3,10,13-trioxo-2,11,12-trioxa-5,8lambda5-diaza-1-ferratetracyclo[6.3.3.0^{1,5 …
Etranacogene dezaparvovec
Hemophilia B - also called factor IX deficiency or Christmas disease - is an X-linked genetic disorder resulting in an absence or deficiency of clotting factor IX. Clotting factors, including factor IX, are necessary components of the signaling cascade responsible for blood clotting and subsequent wound healing. Symptoms of hemophilia...
Approved
Investigational
Prazosin
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists.
Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Synonyms: … 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline ... 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Salts cas: … 19237-84-4 …
Matched Products: … Prazosin-5 Tab ... APO-PRAZO TABLET 5 mg ... NOPRES 5 MG TABLET, 30 ADET …
Matched Iupac: … 2-[4-(furan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Salts cas: … 19237-84-4 …
Matched Products: … Prazosin-5 Tab ... APO-PRAZO TABLET 5 mg ... NOPRES 5 MG TABLET, 30 ADET …
Displaying drugs 1501 - 1525 of 7374 in total