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Displaying drugs 1526 - 1550 of 1920 in total

Apixaban

Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases[Label,A6897]. It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28,...
Approved
Matched Description: … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa ... , as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic …
Matched Categories: … Blood and Blood Forming Organs ... Protease Inhibitors ... Serine Protease Inhibitors …
Matched Products: … Eliquis 5mg film-coated tablets ... Eliquis 2.5mg film-coated tablets ... Apexib 5mg Film Coated Tablets …

Palbociclib

Palbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as...
Approved
Investigational
Matched Description: … electronic health records demonstrating safety and clinical efficacy. ... inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and ... on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … IBRANCE FILM COATED TABLET 75MG ... IBRANCE FILM COATED TABLET 100MG ... IBRANCE FILM COATED TABLET 125MG …

Pazopanib

Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.
Approved
Matched Description: … It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009. ... Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds ... Protein Kinase Inhibitors …
Matched Products: … VOTRIENT FILM-COATED TABLET 200MG ... VOTRIENT FILM-COATED TABLET 400MG ... Pazorene 200mg Film Coated Tablets …

Choline alfoscerate

A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]
Experimental
Investigational
Matched Synonyms: … (2R)-2,3-dihydroxypropyl 2-(trimethylammonio)ethyl phosphate …
Matched Description: … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Categories: … Sulfur Compounds …
Matched Products: … Latuda Film-Coated Tablets 20mg ... Latuda Film-Coated Tablets 40mg ... Latuda Film-Coated Tablets 80mg …

Baloxavir marboxil

Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of baloxavir with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl...
Approved
Investigational
Matched Iupac: … yl]-9,12-dioxo-5-oxa-1,2,8-triazatricyclo[8.4.0.0^{3,8}]tetradeca-10,13-dien-11-yl]oxy}methyl methyl carbonate …
Matched Categories: … Baloxavir and prodrugs ... Sulfur Compounds …
Matched Products: … XOFLUZA FILM-COATED TABLET 40MG ... XOFLUZA FILM COATED TABLETS 20MG ... XOFLUZA FILM COATED TABLETS 40MG …

Perampanel

Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning...
Approved
Matched Description: … It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for ... The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and …
Matched Products: … FYCOMPA FILM-COATED TABLET 6MG ... FYCOMPA FILM-COATED TABLET 12MG ... FYCOMPA FILM-COATED TABLET 8MG …

Dolutegravir

Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Description: … The effect of this drug has no homology in human host cells, which gives it excellent tolerability and ... [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. …
Matched Mixtures name: … TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET ... TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,FILM KAPLI TABLET, 30 ADET ... TRIUMEQ FILM COATED TABLET 50mg/600mg/300mg …
Matched Salts name: … Dolutegravir sodium …
Matched Categories: … lamivudine and dolutegravir ... dolutegravir and rilpivirine ... lamivudine, abacavir and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … TIVICAY FILM-COATED TABLET 25MG ... TIVICAY FILM-COATED TABLET 10MG ... Tivicay 50mg Film-Coated Tablets …

Tadalafil

Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Description: … that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Mixtures name: … TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET ... TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADET …
Matched Categories: … ambrisentan and tadalafil ... tamsulosin and tadalafil ... finasteride and tadalafil ... Genito Urinary System and Sex Hormones ... macitentan and tadalafil …
Matched Products: … MYESED 10MG FILM KAPLI TABLET ,2 FILM TABLET ... MYESED 10MG FILM KAPLI TABLET ,4 FILM TABLET ... MYESED 10MG FILM KAPLI TABLET ,8 FILM TABLET …

Tert-butyl N-[(2S,5R)-6-[[(2S)-5-amino-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-benzyl-3,6-dioxo-1-phenylhexan-2-yl]carbamate

Experimental
Matched Name: … -1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-benzyl-3,6-dioxo-1-phenylhexan-2-yl]carbamate …
Matched Iupac: … -carbamoyl-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propyl]carbamoyl}-3-oxo-1-phenylpentan-2-yl]carbamate …

Linagliptin

Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Description: … that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and ... obeys concentration dependant protein binding[A37050]. …
Matched Mixtures name: … Glyxambi Film-Coated Tablets 25mg/5mg ... Glyxambi Film-Coated Tablets 10mg/5mg ... GLYXAMBI FILM-COATED TABLETS 25 MG/5 MG …
Matched Categories: … Protease Inhibitors ... Alimentary Tract and Metabolism ... metformin and linagliptin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin …
Matched Products: … TRAJENTA 5MG FILM-COATED TABLETS ... SNOXX 5 MG FİLM KAPLI TABLET ... TRAJENTA 5 MG FILM KAPLI TABLET …

Clopidogrel

Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Mixtures name: … CoPlavix Film-Coated Tablet 75 mg/100 mg ... CoPlavix 75/100mg Film-Coated Tablet …
Matched Categories: … Blood and Blood Forming Organs ... Sulfur Compounds …
Matched Products: … Plavix Film-Coated Tablet 300 mg ... MYOCLIP FILM COATED TABLET 75MG ... PLATEL FILM COATED TABLETS 75MG …

Cinacalcet

Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Description: … and as Mimpara® in Europe. ... Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Calcium Homeostasis ... Calcium-sensing Receptor Agonist …
Matched Products: … CİNESET 90 MG FİLM TABLET, 28 ADET ... CALCELAR 25mg Film Coated Tablet ... VISCAP 30 MG FILM TABLET, 28 ADET …

Morphine

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and ... Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. …
Matched Salts name: … Morphine phosphate …
Matched Categories: … morphine and antispasmodics …
Matched Products: … Bar-morphine SR ... MORFIA CR 30 MG FILM TABLET ,20-FILM-TABLET ... MORFIA CR 60 MG FILM TABLET ,20-FILM-TABLET …

Apremilast

Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Aprezo 30mg Film Coated Tablets ... OPRELAST 30 MG FİLM KAPLI TABLET ... Aprezo 20mg Film Coated Tablets …

Venetoclax

Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Description: … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic ... chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), with or without 17p deletion, who ... cell death) process [A18565], [A18566]. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sulfur Compounds …
Matched Products: … VENCLEXTA FILM-COATED TABLET 10MG ... VENCLEXTA FILM-COATED TABLET 50MG ... VENCLEXTA FILM-COATED TABLET 100MG …

Arnica montana flower

Arnica montana flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Arnica Montana Oil …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops …

Entecavir

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS). Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... Food and Drug Administration (FDA) in March 2005. ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTEFIL 1 MG FILM TABLET ,FILM TABLET, 30 ADET ... ENTEFIL 0.5 MG FILM TABLET ,FILM TABLET, 30 ADET ... ENTEVIR FILM-COATED TABLET 1MG …

Vonoprazan

Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Description: … Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require ... In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and ... In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and …
Matched Categories: … Sulfur Compounds ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... vonoprazan, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and metronidazole …
Matched Products: … Vocinti 20mg Film-Coated Tablet ... Vocinti 10mg Film-Coated Tablet ... VOCINTI FILM-COATED TABLET 20MG …

Asciminib

Asciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein which serves as a driver of CML proliferation in most patients with the disease....
Approved
Investigational
Matched Description: … Existing inhibitors of ABL compete at the ATP binding sites of these proteins and can be classified into ... and locking it into an inactive conformation. ... those that target the active conformation of the kinase domain ([dasatinib], [bosutinib]) and those …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … Scemblix 20mg film-coated tablet ... Scemblix 40mg film-coated tablet ... AZEVAY 20 MG FİLM KAPLI TABLET , 60 ADET …

Etoricoxib

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Sulfur Compounds …
Matched Products: … ETOXIB FILM-COATED TABLETS 90MG ... ETOXIB FILM-COATED TABLETS 60MG ... ETOXIB FILM-COATED TABLETS 30MG …

Ibrutinib

Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … IMBRUVICA FILM-COATED TABLETS 140MG ... IMBRUVICA FILM-COATED TABLETS 560MG ... IMBRUVICA FILM-COATED TABLETS 420MG …

Solifenacin

Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily. Solifenacin was granted FDA approval on 19 November 2004.
Approved
Matched Description: … muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones ... tamsulosin and solifenacin …
Matched Products: … VESICARE 5 MG FILM-COATED TABLET ... VESICARE 10 MG FILM-COATED TABLET ... BLADITON FILM COATED TABLETS 5MG …

Irbesartan

Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Matched Mixtures name: … Irbesartan and Hydrochlorothiazide ... Irbesartan and Hydrochlorothiazide ... Irbesartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... irbesartan and diuretics ... irbesartan and amlodipine ... irbesartan, amlodipine and hydrochlorothiazide …
Matched Products: … ERBETAN FILM-COATED TABLET 150MG ... ERBETAN FILM-COATED TABLET 300MG ... Tensiber Film Coated Tablet 150mg …

Cefdinir

Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched Description: … to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and ... Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially …
Matched Mixtures name: … CEFBIR PLUS 300/125 MG FILM KAPLI TABLET, 20 ADET ... FULLCEF PLUS 300/125 MG FILM KAPLI TABLET, 20 ADET …
Matched Categories: … Sulfur Compounds …
Matched Products: … ASEMAX 300 MG FILM TABLET, 14 ADET ... ASEMAX 600 MG FILM KAPLI TABLET, 14 ADET ... ASEMAX 600 MG FILM KAPLI TABLET ,10 TABLET …
Displaying drugs 1526 - 1550 of 1920 in total