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Displaying drugs 1651 - 1675 of 1860 in total

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. ... [L40928] It is also used for high-conditioning before hematopoietic stem cell transplant. ... [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group …
Matched Mixtures name: … Melphalan for Injection ... Melphalan for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan for Injection ... ALKERAN FOR INJECTION 50 mg/vial …

Etoposide

A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Etoposide acts primarily in the G2 and S phases of the cell cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Salts name: … Etoposide phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … MYLAN ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20MG/ML ... ETOPOSIDE CONCENTRATE FOR SOLUTION FOR INJECTION 20mg/ml …

Epirubicin

An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 10mg ... EPIROL Epirubicin Hydrochloride Powder for Solution for Injection 50mg ... Epirubicin for Injection …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … Certain population subgroups in these areas, however, are at high risk (see Indications and Clinical ... There is no specific treatment for hepatitis. ... The hepatitis B virus induces a severe form of viral hepatitis. …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antiinfectives for Systemic Use ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B …
Matched Products: … Engerix-B 20 Adult Dose Suspension for Injection ... Engerix-B 10 Junior Dose Suspension for Injection ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML …

Ioflupane I-123

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Description: … Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes …
Matched Products: … DATSCAN SOLUTION FOR INJECTION 74 MBQ/ML …

3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE

Experimental
Matched Name: … 3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE …
Matched Iupac: … (2S,3R)-3-formyl-N,2-dihydroxy-5-methylhexanamide …

Lenograstim

Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … GRANOCYTE 34 FOR INJECTION 263 mcg/ml …

Temsirolimus

Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sirolimus and Prodrugs …
Matched Products: … Torisel Concentrate for Injection 25mg/mL …

Ganirelix

Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist ... Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ORGALUTRAN 0.25MG/0.5ML (SOLUTION FOR INJECTION) ... ORGALUTRAN SOLUTION FOR INJECTION 0.25 mg/0.5 ml …

Polymyxin B

Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Description: … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic ... It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused ... Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line …
Matched Mixtures name: … Poly-pred ... Polysporin for Kids ... Polysporin for Stitches …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Ophthalmological and Otological Preparations ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Polymyxin B for Injection USP ... POLY-MxB for Injection U.S.P. 500,000 Units (Lyophilized) …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability ... It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. …
Matched Mixtures name: … POMADA MONTAÑA ... Acerbine - Salbe ... Sodium Phenylacetate and Sodium Benzoate …
Matched Salts name: … Sodium benzoate …
Matched Categories: … sodium benzoate and sodium phenylacetate ... caffeine and sodium benzoate ... Tests for Gastric Secretion ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … S Panax Mist for Refill …

(2S)-2,3-bis{[(3R,7R)-3,7,11,15-tetramethylhexadecyl]oxy}propyl (2R)-2-hydroxy-3-[(hydroxyphosphinato)oxy]propyl phosphate

Experimental
Matched Name: … [(3R,7R)-3,7,11,15-tetramethylhexadecyl]oxy}propyl (2R)-2-hydroxy-3-[(hydroxyphosphinato)oxy]propyl phosphate …

Selenium

Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Approved
Investigational
Vet approved
Matched Description: … of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and …
Matched Mixtures name: … Card-floe II Tab ... Multi Flow Tablets ... Multivitamins and Minerals for Men …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … selenase 500 micrograms, solution for injection (50 micrograms/ml) ... selenase ® 100 micrograms, solution for injection (50 micrograms/ml) …

Calfactant

Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Description: … 0.65mg of proteins including surfactant-associated proteins B and C. ... phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and ... decrease the incidence of respiratory distress syndrome, mortality due to respiratory distress syndrome, and …
Matched Products: … BLES (bovine lipid extract surfactant) 27 mg/ml Suspension for Intratracheal Instillation …

4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose

Experimental
Matched Synonyms: … 4,6-Dideoxy-4-{[(1s,5r,6s)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-d-xylo-hex-5-enopyranose …
Matched Name: … 4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose …

Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... widely prescribed in the Netherlands, New Zealand, and the US. ... [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is …
Matched Mixtures name: … Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide …
Matched Categories: … Antihypertensive Agents Indicated for Hypertension ... Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... Beta Blocking Agents, Selective, and Thiazides ... metoprolol and felodipine …
Matched Products: … BELOC ZOK FORTE 190MG ... BELOC ZOK 25 MG KONTROLLÜ SALIM TABLET, 20 ADET …

Cetuximab

Cetuximab is a recombinant chimeric human/mouse IgG1 monoclonal antibody that competitively binds to epidermal growth factor receptor (EGFR) and competitively inhibits the binding of epidermal growth factor (EGF). EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible...
Approved
Matched Description: … cells; it is responsible for regulating epithelial tissue development and homeostasis. ... [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for ... the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ERBITUX 5MG/ML SOLUTION FOR INFUSION …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Description: … Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is ... used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … Mesna for Injection ... CONCENTRATE SOLUTION FOR INJECTION 400MG/4ML …

Indacaterol

Indacaterol is a novel, ultra-long-acting, rapid onset β(2)-adrenoceptor agonist developed for Novartis for the once-daily management of asthma and chronic obstructive pulmonary disease. It was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as...
Approved
Matched Description: … for the once-daily management of asthma and chronic obstructive pulmonary disease. ... Indacaterol is provided as its maleate salt form. ... It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. …
Matched Categories: … indacaterol and mometasone ... indacaterol and glycopyrronium bromide ... indacaterol, glycopyrronium bromide and mometasone ... Drugs for Obstructive Airway Diseases …
Matched Products: … Onbrez Breezhaler Powder for inhalation Hard Capsule 300 mcg ... Onbrez Breezhaler Powder for Inhalation Hard Capsule 150 mcg …

Exametazime

Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection. It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous leukocytes.
Approved
Matched Description: … It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous ... It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. ... Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime …
Matched Products: … CERETEC FOR INJECTION 0.5 mg/vial …

Betiatide

Approved
Experimental
Matched Products: … Kit for the Preparation of Technetium Tc99m Mertiatide …

Alanyl glutamine

Alanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Kipo for IV Infusion 200 mg/ml …

Hyaluronidase

Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … fluids, drugs, and contrast agents. ... Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … HYALASE POWDER FOR INJECTION 1500 iu/ampoule …

Kanamycin

Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate.
Approved
Investigational
Vet approved
Matched Description: … intramuscular forms, and used to treat a wide variety of infections. ... Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is ... known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and …
Matched Categories: … Alimentary Tract and Metabolism ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … KANAMYCIN MEIJI FOR INJECTION 1 g/vial …

Aedes taeniorhynchus

Aedes taeniorhynchus allergenic extract is used in allergenic testing.
Approved
Matched Products: … Mosquito for Diagnostic Use Only …
Displaying drugs 1651 - 1675 of 1860 in total