Displaying drugs 1676 - 1700 of 2293 in total
Levosalbutamol
Levosalbutamol, or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).
Salbutamol has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has...
Approved
Investigational
Matched Description: … , or levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and ... The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects …
Matched Salts name: … Levosalbutamol hydrochloride …
Matched Products: … Levalbuterol Hydrochloride …
Matched Salts name: … Levosalbutamol hydrochloride …
Matched Products: … Levalbuterol Hydrochloride …
Quinapril
Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval...
Approved
Investigational
Matched Description: … [L8420,L8423] It is used to treat hypertension and heart failure. …
Matched Mixtures name: … Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Quinapril Hydrochloride …
Matched Categories: … ACE Inhibitors and Diuretics ... quinapril and diuretics …
Matched Products: … Quinapril Hydrochloride …
Matched Mixtures name: … Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide ... Quinapril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Quinapril Hydrochloride …
Matched Categories: … ACE Inhibitors and Diuretics ... quinapril and diuretics …
Matched Products: … Quinapril Hydrochloride …
Oxybuprocaine
Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Salts name: … Oxybuprocaine hydrochloride …
Matched Products: … Minims Benoxinate Hydrochloride 0.4% …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Salts name: … Oxybuprocaine hydrochloride …
Matched Products: … Minims Benoxinate Hydrochloride 0.4% …
(4R)-limonene 1α,2α-epoxide
Experimental
Matched Synonyms: … (1S,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptane …
Matched Iupac: … (1R,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane …
Matched Iupac: … (1R,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane …
Prenylamine
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … N-(1-Methyl-2-phenylethyl)-gamma-phenylbenzenepropanamine …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Salts name: … Prenylamine lactate …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Salts name: … Prenylamine lactate …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Deoxyepinephrine
Sympathomimetic, vasoconstrictor agent.
Experimental
Matched Synonyms: … N-methyl-3,4-dihydroxyphenethylamine …
Matched Salts name: … Deoxyepinephrine hydrochloride …
Matched Categories: … Epinephrine and similars …
Matched Salts name: … Deoxyepinephrine hydrochloride …
Matched Categories: … Epinephrine and similars …
H3B-8800
H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting . H3B-8800 was granted orphan drug status by the FDA in August 2017 and...
Investigational
Matched Synonyms: … )-1-METHYL-5-(2-PYRIDINYL)-1,3-HEXADIEN-1-YL)-12-OXOOXACYCLODODEC-4-EN-6-YL ESTER ... Dihydroxy-3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(2-pyridinyl)-2,4-heptadien-2-yl]oxacyclododec-4-en-6-yl 4-methyl ... 1-PIPERAZINECARBOXYLIC ACID, 4-METHYL-, (2S,3S,4E,6S,7R,10R)-7,10-DIHYDROXY-3,7-DIMETHYL-2-((1E,3E,5R …
Matched Description: … of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551]. ... H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment …
Matched Description: … of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551]. ... H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment …
Trioxsalen
Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of...
Approved
Matched Synonyms: … 6-hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid, δ-lactone …
Matched Description: … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative ... conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage …
Matched Description: … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative ... conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage …
H3B-6527
H3B-6527 is under investigation in clinical trial NCT03424577 (A Study to Evaluate the Food-Effect of H3B-6527).
Investigational
Matched Synonyms: … (N-{2-[(6-{[(2,6-Dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4- yl)amino]-5-(4-ethylpiperazin ... N-(2-((6-(((2,6-DICHLORO-3,5 DIMETHOXYPHENYL) CARBAMOYL) (METHYL)AMINO)PYRIMIDIN-4-YL)AMINO)-5-(4-ETHYLPIPERAZIN …
Matched Iupac: … N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin …
Matched Iupac: … N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin …
Venlafaxine
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and …
Matched Salts name: … Venlafaxine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Venlafaxine hydrochloride ... Venlafaxine Hydrochloride ... Venlafaxine Hydrochloride ER …
Matched Salts name: … Venlafaxine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Venlafaxine hydrochloride ... Venlafaxine Hydrochloride ... Venlafaxine Hydrochloride ER …
Doxepin
Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to cidoxepin. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. In a strict sense, doxepin is not a tricyclic antidepressant but...
Approved
Investigational
Matched Description: … Doxepin is a psychotropic agent with antidepressant and anxiolytic properties. ... [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer ... [L5977]
Doxepin was developed by Pfizer and FDA approved in 1969 as an antidepressant. …
Matched Salts name: … Doxepin hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Antipruritics and Local Anesthetics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Doxepin Hydrochloride ... Doxepin hydrochloride …
Matched Salts name: … Doxepin hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Antipruritics and Local Anesthetics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Doxepin Hydrochloride ... Doxepin hydrochloride …
Nalbuphine
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid …
Matched Salts name: … Nalbuphine hydrochloride …
Matched Products: … Nalbuphine Hydrochloride …
Matched Salts name: … Nalbuphine hydrochloride …
Matched Products: … Nalbuphine Hydrochloride …
Chromic chloride
Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Matched Synonyms: … anhydrous chromium(III) chloride …
Matched Mixtures name: … Multiple Trace Metal Additive Solution ... Palm Springs Multvit and Min Tab ... Multivitamins and Minerals Tablets …
Matched Mixtures name: … Multiple Trace Metal Additive Solution ... Palm Springs Multvit and Min Tab ... Multivitamins and Minerals Tablets …
Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam
Experimental
Matched Name: … Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam …
(E)-(4S,6S)-8-METHYL-6-((S)-3-METHYL-2-{(S)-2-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-PROPIONYLAMINO}-BUTYRYLAMINO)-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID BENZYL ESTER
Experimental
Matched Name: … (E)-(4S,6S)-8-METHYL-6-((S)-3-METHYL-2-{(S)-2-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-PROPIONYLAMINO} …
Matched Iupac: … benzyl (2E,4S)-4-[(2S)-4-methyl-2-[(2S)-3-methyl-2-[(2S)-2-[(5-methyl-1,2-oxazol-3-yl)formamido]propanamido …
Matched Iupac: … benzyl (2E,4S)-4-[(2S)-4-methyl-2-[(2S)-3-methyl-2-[(2S)-2-[(5-methyl-1,2-oxazol-3-yl)formamido]propanamido …
(E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)-8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER
Experimental
Matched Name: … (E)-(4S,6S)-6-((S)-2-{(S)-2-[(FURAN-2-CARBONYL)-AMINO]-3-METHYL-BUTYRYLAMINO}-3-METHYL-BUTYRYLAMINO)- ... 8-METHYL-5-OXO-4-((R)-2-OXO-PYRROLIDIN-3-YLMETHYL)-NON-2-ENOIC ACID ETHYL ESTER …
Remifentanil
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Iupac: … methyl 1-(3-methoxy-3-oxopropyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate …
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Salts name: … Remifentanil hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Hydrochloride ... Remifentanil Hydrochloride for Injection …
Matched Description: … causes respiratory depression and analgesia. ... Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and ... a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and …
Matched Salts name: … Remifentanil hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Fentanyl and fentanyl analogues …
Matched Products: … Remifentanil Hydrochloride ... Remifentanil Hydrochloride for Injection …
Selpercatinib
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3 …
Matched Iupac: … 6-(2-hydroxy-2-methylpropoxy)-4-(6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3 …
Matched Description: … Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK ... Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 6-(2-hydroxy-2-methylpropoxy)-4-(6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3 …
Matched Description: … Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK ... Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
KTX-1001
Investigational
Matched Synonyms: … (S)-1-((R)-3-amino-1-(4-((6-amino-9H-purin-9-yl)methyl)-6-(2,5-difluoro-4-methoxyphenyl)pyridin-3-yl) …
ABBV-CLS-7262
Investigational
Matched Synonyms: … Sodium ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen …
Matched Iupac: … )propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2-yl]oxy}methyl …
Matched Iupac: … )propane-1,3-diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2-yl]oxy}methyl …
Enzacamene
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … Methyl benzylidene camphor …
Matched Iupac: … (3E)-1,7,7-trimethyl-3-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-2-one …
Matched Description: … Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and …
Matched Mixtures name: … Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen ... mesoestetic moisturizing sun protection BROAD SPECTRUM FOR NORMAL AND DRY SKINS …
Matched Iupac: … (3E)-1,7,7-trimethyl-3-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-2-one …
Matched Description: … Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and …
Matched Mixtures name: … Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen ... mesoestetic moisturizing sun protection BROAD SPECTRUM FOR NORMAL AND DRY SKINS …
2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One
Experimental
Matched Name: … 2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One …
Matched Iupac: … (2S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-one …
Matched Iupac: … (2S)-2-amino-3-methyl-1-(pyrrolidin-1-yl)butan-1-one …
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alanyl-L-alaninamide
Experimental
Matched Name: … N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alanyl-L-alaninamide …
1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE
Experimental
Matched Name: … 1-((2-HYDROXYETHOXY)METHYL)-5-(PHENYLTHIO)PYRIMIDINE-2,4(1H,3H)-DIONE …
Matched Iupac: … 1-[(2-hydroxyethoxy)methyl]-5-(phenylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 1-[(2-hydroxyethoxy)methyl]-5-(phenylsulfanyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Displaying drugs 1676 - 1700 of 2293 in total