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Displaying drugs 151 - 175 of 176 in total

Glycochenodeoxycholic Acid

A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [PubChem]
Experimental
Matched Description: … A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. ... It is a cholagogue and choleretic. [PubChem] ... It acts as a detergent to solubilize fats for absorption and is itself absorbed. …
Matched Categories: … Bile Acids and Salts ... Amino Acids, Peptides, and Proteins …

Potassium bitartrate

Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Matched Description: … Potassium bitartrate has a long history of medical use as a laxative administered as a rectal suppository and …

Ularitide

Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Description: … the excretion of water and sodium from the kidneys. ... When injected into the blood, ularitide appears to cause diuresis (urine output) and natriuresis (sodium ... Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Tetrodotoxin

An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough pain in advanced cancer patients as...
Investigational
Matched Description: … The toxin causes paresthesia and paralysis through interference with neuromuscular conduction. ... Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough ... An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes …
Matched Categories: … Sodium Channel Blockers …

L-tartaric acid

Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
Experimental
Matched Description: … aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid. ... naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and …

Hyodeoxycholic Acid

Hyodeoxycholic Acid has been used in trials studying the treatment of Hypercholesterolemia.
Investigational
Matched Salts name: … Sodium hyodeoxycholate …
Matched Categories: … Bile Acids and Salts …

Monensin

Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
Experimental
Vet approved
Matched Salts name: … Monensin sodium …
Matched Categories: … Sodium Ionophores …

Semduramicin

Vet approved
Matched Salts name: … Semduramicin sodium …

Taurochenodeoxycholic acid

Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile...
Experimental
Matched Description: … It is also being investigated for its role in inflammation and cancer therapy. ... As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely ... used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics …

Hydroxydione

Hydroxydione (Viadril) is a neuroactive steroid used as a general anesthetic.
Investigational
Withdrawn
Matched Salts name: … Hydroxydione sodium …

Volixibat

Volixibat, also known as SHP626 or LUM002, is an investigational drug that will potentially be used for the treatment of Non-Alcoholic Steatohepatitis (NASH). If approved for use, it will be the first available agent for the treatment of NASH. Volixibat is a selective inhibitor of the apical sodium-dependent bile acid...
Experimental
Investigational
Matched Description: … Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane ... ultimately for hepatic lipid and glucose metabolism [A32120]. ... transporter (IBAT), ASBT is primarily responsible for the enterohepatic recirculation of bile acids and …

Refametinib

Investigational

Reproterol

Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
Investigational
Matched Categories: … reproterol and sodium cromoglicate …

Denufosol

Denufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial. A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in...
Investigational
Matched Description: … Denufosol has not gained FDA approval, and clinical trials with this drug have ceased since 2011. ... The drug was also evaluated in the treatment of retinal detachment and other diseases of the retina. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Eritoran

Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational

Betadex

Experimental
Matched Salts name: … Betadex sulfobutyl ether sodium …
Matched Categories: … Diet, Food, and Nutrition …

Salinomycin

Vet approved
Matched Salts name: … Salinomycin sodium …

Tenivastatin

Experimental
Matched Salts name: … Tenivastatin sodium …

Cloprostenol

Vet approved
Matched Salts name: … Cloprostenol sodium …

Fluprostenol

Vet approved
Matched Salts name: … Fluprostenol sodium …

Faropenem

Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
Investigational
Matched Description: … Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and …
Matched Salts name: … Faropenem Sodium …

Guadecitabine

Guadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
Investigational
Matched Salts name: … Guadecitabine Sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Silibinin

Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and others. Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar...
Experimental
Investigational
Matched Description: … both small and nonsmall human lung carcinoma cells. ... Silibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in ... containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …

Flomoxef

Flomoxef has been used in trials studying the treatment of Urinary Tract Infection.
Investigational
Matched Salts name: … Flomoxef Sodium …

Clazosentan

Investigational
Matched Salts name: … Clazosentan Sodium …
Displaying drugs 151 - 175 of 176 in total