Displaying drugs 151 - 175 of 14564 in total
Talazoparib
Talazoparib is an inhibitor of mammalian polyadenosine 5’-diphosphoribose polymerases (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and DNA repair. Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 and by the EMA in June 2019. It was approved by Health Canada...
Approved
Investigational
Matched Iupac: … (11S,12R)-7-fluoro-11-(4-fluorophenyl)-12-(1-methyl-1H-1,2,4-triazol-5-yl)-2,3,10-triazatricyclo[7.3.1.0 …
Matched Description: … [L47301] Talazoparib is currently used in the treatment of BRCA-mutated breast cancer and HRR-mutated ... and by the EMA in June 2019. ... [L47236] Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 [A260346] …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Description: … [L47301] Talazoparib is currently used in the treatment of BRCA-mutated breast cancer and HRR-mutated ... and by the EMA in June 2019. ... [L47236] Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 [A260346] …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Hydroquinone
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … As a result of these concerns, hydroquinone has been banned in the EU and UK. ... Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, …
Matched Mixtures name: … REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERS Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots Travel Size …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Light The Way ... SLMD Skincare by Sandra Lee, M.D. - Dark Spot Fix …
Matched Mixtures name: … REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERS Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots Travel Size …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Light The Way ... SLMD Skincare by Sandra Lee, M.D. - Dark Spot Fix …
Ofatumumab
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … [A6921] Ofatumumab was first approved by the FDA in 2009. ... [L12612] Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers ... Authorization Application (MAA), respectively, for ofatumumab for the treatment of RMS in adults. …
Matched Categories: … CD20 (Clusters of Differentiation 20) inhibitors …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (1 ADET) ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe …
Matched Categories: … CD20 (Clusters of Differentiation 20) inhibitors …
Matched Products: … İNFÜZYONLUK ÇÖZELTİ KONSATRESİ İÇEREN FLAKON (1 ADET) ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe …
Diphenhydramine
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect ... While its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine ... As histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has …
Matched Salts cas: … 31065-89-1 …
Matched Mixtures name: … Cathejell Diphenhydramin 1 % / Chlorhexidin 0,05 % - Gel (in Tuben) ... NORAVER® NF NOCHE ... healthy mama eaZZZe THE PAIN …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … A Health Itch Relief Gel ... ZzzQuil FREE OF ... Allergy Relief, 24-7 Lift by 7-Eleven …
Matched Salts cas: … 31065-89-1 …
Matched Mixtures name: … Cathejell Diphenhydramin 1 % / Chlorhexidin 0,05 % - Gel (in Tuben) ... NORAVER® NF NOCHE ... healthy mama eaZZZe THE PAIN …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … A Health Itch Relief Gel ... ZzzQuil FREE OF ... Allergy Relief, 24-7 Lift by 7-Eleven …
Vincristine
Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate...
Approved
Investigational
Matched Description: … Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, ... because of lack of significant bone–marrow suppression (at recommended doses) and of unique clinical ... It is marketed under several brand names, many of which have different formulations such as Marqibo ( …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Products: … CYTOCRISTIN AQUEOUS (VL OF 1ML) ... SULFATO DE VINCRISTINA 1 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE. ... VINARIX 1 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Products: … CYTOCRISTIN AQUEOUS (VL OF 1ML) ... SULFATO DE VINCRISTINA 1 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE. ... VINARIX 1 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Aztreonam
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl) -2- {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene ... (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino …
Matched Iupac: … -4-oxoazetidine-1-sulfonate ... (2S,3S)-3-[(2Z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl …
Matched Description: … It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges ... It may cause a superinfection with gram-positive organisms. ... A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZACTAM ® 1 G ... AZBIOS® 1G POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... AZTREONAM 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Iupac: … -4-oxoazetidine-1-sulfonate ... (2S,3S)-3-[(2Z)-2-(2-azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl …
Matched Description: … It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges ... It may cause a superinfection with gram-positive organisms. ... A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … AZACTAM ® 1 G ... AZBIOS® 1G POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... AZTREONAM 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Ammonia
Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Although ammonia is used as a food additive in the anhydrous form and serves as a...
Approved
Matched Description: … protein by the Krebs-Hanseleit cycle in the liver [L2033]. ... up by glutamic acid and take part in transamination and other reactions, including the synthesis of ... Although ammonia is used as a food additive in the anhydrous form and serves as a starting material in …
Matched Products: … After Bite The Itch Eraser KIDS ... After Bite The Itch Eraser Xtra …
Matched Products: … After Bite The Itch Eraser KIDS ... After Bite The Itch Eraser Xtra …
Romidepsin
Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy.
Approved
Investigational
Matched Description: … Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment ... of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy …
Matched Categories: … Organic Anion Transporter 1 Inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … Organic Anion Transporter 1 Inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Theophylline
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac ... Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and …
Matched Mixtures name: … TUSBRON-A JARABE ... Theophylline in Dextrose ... Theophylline in Dextrose …
Matched Categories: … combinations of xanthines ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Theophylline in Dextrose …
Matched Mixtures name: … TUSBRON-A JARABE ... Theophylline in Dextrose ... Theophylline in Dextrose …
Matched Categories: … combinations of xanthines ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Theophylline in Dextrose …
Benzoyl peroxide
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … Benzoyl peroxide is a commonly used drug in topical treatments for acne. ... A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover of ... [L33314] After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically …
Matched Mixtures name: … Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Clear Proof Acne System The Go Set ... CLOZARYL %1+%5 JEL, 25 GRAM …
Matched Products: … Dual-shave 2 In 1 ... Dual-shave 2 In 1 for Her ... Advanced 3 in 1 Exfoliating Cleanser …
Matched Mixtures name: … Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Clear Proof Acne System The Go Set ... CLOZARYL %1+%5 JEL, 25 GRAM …
Matched Products: … Dual-shave 2 In 1 ... Dual-shave 2 In 1 for Her ... Advanced 3 in 1 Exfoliating Cleanser …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … Combination therapy of ribavirin and [DB00008] results in the SVR of 44% in patients with genotype 1 ... Ribavirin is added to decrease relapse rates by accelerating viral clearance early in the treatment course ... The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Products: … COPEGUS 200 MG FILM KAPLI TABLET, 42 ADET …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … Combination therapy of ribavirin and [DB00008] results in the SVR of 44% in patients with genotype 1 ... Ribavirin is added to decrease relapse rates by accelerating viral clearance early in the treatment course ... The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Products: … COPEGUS 200 MG FILM KAPLI TABLET, 42 ADET …
Fremanezumab
Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. ... Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide ... (CGRP) for the prevention of migraine headaches. …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Matched Products: … AJOVY 225 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Matched Products: … AJOVY 225 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …
Mineral oil
Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. Petroleum mineral oil is manufactured from crude oils by vacuum distillation to produce several distillates and a residual oil that are then further refined. During the modern refining process, aromatics are reduced...
Approved
Vet approved
Matched Description: … Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum ... Mineral oil is a common ingredient in baby lotions, cold creams, ointments and cosmetics to treat and ... During the modern refining process, aromatics are reduced by solvent extraction, catalytic hydrotreating …
Matched Mixtures name: … AGAROL CON SABOR A FRAMBUESA ... Milk Of Magnesia Mineral Oil Emulsion ... Milk Of Magnesia Mineral Oil Emulsion …
Matched Products: … The Grid ... Gelee Laxative A LA Framboise ... Mizon No.1 Kingsberry Cleansing Oi L …
Matched Mixtures name: … AGAROL CON SABOR A FRAMBUESA ... Milk Of Magnesia Mineral Oil Emulsion ... Milk Of Magnesia Mineral Oil Emulsion …
Matched Products: … The Grid ... Gelee Laxative A LA Framboise ... Mizon No.1 Kingsberry Cleansing Oi L …
Triclosan
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, ... skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, …
Matched Mixtures name: … Colgate Total Clean in Between ... PREVENT 2 EN 1 ... KURSEPT %19 + %1 KREM (30 G) …
Matched Products: … Antibacterial Body Wash Spring Water 2 in 1 ... 3 in 1 Antibacterial Hair and Body Wash ... Cetaphil MEN 3-in-1 Active Antibacterial Bar …
Matched Mixtures name: … Colgate Total Clean in Between ... PREVENT 2 EN 1 ... KURSEPT %19 + %1 KREM (30 G) …
Matched Products: … Antibacterial Body Wash Spring Water 2 in 1 ... 3 in 1 Antibacterial Hair and Body Wash ... Cetaphil MEN 3-in-1 Active Antibacterial Bar …
Iron
A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched International brands: … Ed-In-Sol ... Fer-In-Sol …
Matched Description: … Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms ... A metallic element found in certain minerals, in nearly all soils, and in mineral waters. ... Iron is used to build up the blood in anemia. …
Matched Mixtures name: … UltimateCare ONE NF ... PNV Tabs 29-1 ... PNV Tabs 29-1 …
Matched Products: … FER-IN-SOL ... COMPLEJO DE HIDROXIDO DE HIERRO EN SACAROSA EQUIVALENTE A 100 MG DE HIERRO ELEMENTAL INYECTABLE …
Matched Description: … Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms ... A metallic element found in certain minerals, in nearly all soils, and in mineral waters. ... Iron is used to build up the blood in anemia. …
Matched Mixtures name: … UltimateCare ONE NF ... PNV Tabs 29-1 ... PNV Tabs 29-1 …
Matched Products: … FER-IN-SOL ... COMPLEJO DE HIDROXIDO DE HIERRO EN SACAROSA EQUIVALENTE A 100 MG DE HIERRO ELEMENTAL INYECTABLE …
Donislecel
Donislecel is the first allogeneic pancreatic islet cellular from deceased donor pancreatic cells used for the treatment of adult type 1 diabetes with unsuccessful control of glycated hemoglobin, despite intensive diabetes management and treatments.[L47166,L47196] The primary mechanism of action of donislecel is attributed to the secretion of insulin and other...
Approved
Matched Description: … [L47166,L47196] The approval of donislecel was based on the safety and effectiveness evaluated in 2 clinical ... for the treatment of adult type 1 diabetes with unsuccessful control of glycated hemoglobin, despite ... [L47166,L47196] The primary mechanism of action of donislecel is attributed to the secretion of insulin …
Matched Categories: … Drugs Used in Diabetes ... Cellular and Gene Therapy …
Matched Categories: … Drugs Used in Diabetes ... Cellular and Gene Therapy …
Capmatinib
Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades involved in organ regeneration and tissue repair. Aberrant c-Met activation - via mutations, amplification, and/or overexpression - is known to occur in many...
Approved
Investigational
Matched Description: … [A199122] This co-occurrence has made c-Met a desirable target in the treatment of NSCLC. ... approval by the FDA on May 6, 2020,[L13380] for the treatment of NSCLC in patients whose tumors have ... a mutation that leads to mesenchymal-epithelial transition (MET) exon 14 skipping. …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Atorvastatin
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Iupac: … (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic …
Matched Description: … By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol ... Bruce Roth and approved by the FDA in 1996. ... Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. …
Matched Mixtures name: … TIAZOMET ® A 40/10 TABLETAS …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol ... Bruce Roth and approved by the FDA in 1996. ... Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. …
Matched Mixtures name: … TIAZOMET ® A 40/10 TABLETAS …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Venetoclax
Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Synonyms: … 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro ... 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro ... -4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- …
Matched Description: … Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. ... Previously, this drug was indicated only for patients with 17p gene deletion [F2130]. ... Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- …
Matched Description: … Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. ... Previously, this drug was indicated only for patients with 17p gene deletion [F2130]. ... Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Epinephrine
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Synonyms: … 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol …
Matched Description: … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal ... Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector ... In general, the most common uses of parenteral epinephrine are to relieve respiratory distress due to …
Matched Salts cas: … 51-42-3 ... 97289-42-4 …
Matched Mixtures name: … The Solution ... The Solution Anorectal Spray Temporary Pain Relief ... N/A …
Matched Categories: … Sympathomimetics in Glaucoma Therapy ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists …
Matched Products: … Adrenalin Aguettant 1 mg/10 ml (1:10.000) Injektionslösung in einer Fertigspritze ... Jext 150 Mikrogramm Injektionslösung in einem Fertigpen ... Jext 300 Mikrogramm Injektionslösung in einem Fertigpen …
Matched Iupac: … 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol …
Matched Description: … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal ... Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector ... In general, the most common uses of parenteral epinephrine are to relieve respiratory distress due to …
Matched Salts cas: … 51-42-3 ... 97289-42-4 …
Matched Mixtures name: … The Solution ... The Solution Anorectal Spray Temporary Pain Relief ... N/A …
Matched Categories: … Sympathomimetics in Glaucoma Therapy ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists …
Matched Products: … Adrenalin Aguettant 1 mg/10 ml (1:10.000) Injektionslösung in einer Fertigspritze ... Jext 150 Mikrogramm Injektionslösung in einem Fertigpen ... Jext 300 Mikrogramm Injektionslösung in einem Fertigpen …
Turoctocog alfa
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification ... Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence …
Matched Products: … NOVOEIGHT® 1500 UI POLVO ESTERIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... NOVOEİGHT 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... NOVOEİGHT 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Matched Products: … NOVOEIGHT® 1500 UI POLVO ESTERIL PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... NOVOEİGHT 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... NOVOEİGHT 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity ... of bacterial DNA gyrase, halting DNA replication. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity ... of bacterial DNA gyrase, halting DNA replication. …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Filgrastim
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood. ... [L40719] It has a number of therapeutic uses, including the management and prevention of infections and ... [L40714] Human G-CSF is a glycoprotein that regulates the production and release of neutrophils from …
Matched Products: … ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML ... ACCOFIL 48 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 48 MU/0.5 ML …
Matched Products: … ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML ... ACCOFIL 48 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 48 MU/0.5 ML …
Insulin degludec
Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … by Type 1 and Type 2 Diabetes. ... 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas ... , resulting in the body not being able to produce or synthesize the insulin needed to manage circulating …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 100 U/ML ... TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 200 U/ML ... TRESIBA FLEXTOUCH 100 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 100 U/ML ... TRESIBA® FLEXTOUCH® SOLUTION FOR INJECTION IN PRE-FILLED PEN 200 U/ML ... TRESIBA FLEXTOUCH 100 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Mifepristone
Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome....
Approved
Investigational
Matched Iupac: … ,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1S,3aS,3bS,10R,11aS)-10-[4-(dimethylamino)phenyl]-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1H,2H,3H,3aH …
Matched Description: … Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing ... As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients ... The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Description: … Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing ... As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients ... The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Displaying drugs 151 - 175 of 14564 in total