Displaying drugs 1751 - 1775 of 2924 in total
VMD-928
Investigational
Matched Synonyms: … 4-((4-AMINO-3-(4-CYCLOHEXYLPIPERAZIN-1-YL)-9,10-DIOXO-9,10-DIHYDROANTHRACEN-1-YL)AMINO)BENZOIC ACID ... 4-{[4-Amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid ... BENZOIC ACID, 4-((4-AMINO-3-(4-CYCLOHEXYL-1-PIPERAZINYL)-9,10-DIHYDRO-9,10-DIOXO-1-ANTHRACENYL)AMINO) …
Matched Iupac: … 4-{[4-amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid …
Matched Iupac: … 4-{[4-amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid …
Sirpiglenastat
Sirpiglenastat, also known as DRP-104, is a prodrug of 6-diazo-5-oxo-L-norleucine (DON), which is a broad-acting glutamine antagonist. It is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in Adults With Advanced Solid Tumors).
Investigational
Matched Synonyms: … L-norleucine, n-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl ester ... Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoate …
Matched Description: … also known as DRP-104, is a prodrug of [6-diazo-5-oxo-L-norleucine] (DON), which is a broad-acting glutamine …
Matched Description: … also known as DRP-104, is a prodrug of [6-diazo-5-oxo-L-norleucine] (DON), which is a broad-acting glutamine …
Zomepirac
Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Withdrawn
Matched Synonyms: … 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Description: … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid ... The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983 …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid …
Matched Description: … Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid ... The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983 …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Glucarpidase
Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified Escherichia coli bacteria. It is a 390-amino acid homodimer protein. High-dose methotrexate, an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin rescue, some patients...
Approved
Investigational
Matched Synonyms: … Pteroylmonoglutamic acid hydrolase G2 …
Matched Description: … It is a 390-amino acid homodimer protein. ... [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... gamma-Glutamyl Hydrolase, antagonists & inhibitors …
Matched Description: … It is a 390-amino acid homodimer protein. ... [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... gamma-Glutamyl Hydrolase, antagonists & inhibitors …
Indium In-111 pentetate
Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column.
Approved
Matched Synonyms: … Indium (111In) pentetic acid …
Matched Iupac: … (111In)indium(3+) ion 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetate …
Matched Description: … In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and …
Matched Categories: … indium (111In) pentetic acid …
Matched Iupac: … (111In)indium(3+) ion 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetate …
Matched Description: … In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and …
Matched Categories: … indium (111In) pentetic acid …
Acamprosate
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … 3-Acetamido-1-propanesulfonic acid …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Matched Description: … It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... economic consequences resulting from accidents, violence, incarceration, decreased productivity, and …
Matched Categories: … Sulfur Acids ... Sulfonic Acids …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Matched Description: … It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... economic consequences resulting from accidents, violence, incarceration, decreased productivity, and …
Matched Categories: … Sulfur Acids ... Sulfonic Acids …
Oleoyl-estrone
Oleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans. It has been shown in animal studies to promote the loss of body fat while maintaining body protein storage, maintaining nitrogen balance. Body protein loss is an...
Investigational
Matched Synonyms: … Estrone oleic acid ester …
Matched Description: … Oleoyl-estrone (OE) is a fatty acid ester of estrone. ... This hormone occurs naturally and is found circulating in various animal species and humans. ... Body protein loss is an unpleasant effect of fat loss by the restriction of calories, and studies show …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Description: … Oleoyl-estrone (OE) is a fatty acid ester of estrone. ... This hormone occurs naturally and is found circulating in various animal species and humans. ... Body protein loss is an unpleasant effect of fat loss by the restriction of calories, and studies show …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Bicyclol
Bicyclol is under investigation in clinical trial NCT02944552 (The Multi Center, Randomized, Double-blind, Positive Controlled Study of Bicyclol in the Treatment of Acute DILI).
Investigational
Matched Synonyms: … 4,4'-bi-1,3-benzodioxole)-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester …
Vonafexor
Investigational
Matched Synonyms: … 2-benzofurancarboxylic acid, 4-chloro-5-(4-((2,6-dichlorophenyl)sulfonyl)-1-piperazinyl)- …
Adapalene
Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Description: … multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and ... [A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and ... can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties[A193524], and …
Matched Mixtures name: … Adapalene and Benzoyl Peroxide ... ADAPALENE and BENZOYL PEROXIDE ... Adapalene and Benzoyl Peroxide …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Description: … multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and ... [A193521] [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and ... can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties[A193524], and …
Matched Mixtures name: … Adapalene and Benzoyl Peroxide ... ADAPALENE and BENZOYL PEROXIDE ... Adapalene and Benzoyl Peroxide …
Matched Categories: … Skin and Mucous Membrane Agents …
Ambrisentan
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Synonyms: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid …
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and …
Matched Categories: … ambrisentan and tadalafil ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid …
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and …
Matched Categories: … ambrisentan and tadalafil ... Acids, Carbocyclic ... Carboxylic Acids …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid ... 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Acids, Heterocyclic …
Thiopental
A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Synonyms: … Thiopentobarbituric acid ... 2-Thio-5-ethyl-5-sec-pentylbarbituric acid …
Matched Description: … It is also used for hypnosis and for the control of convulsive states. ... Small doses have been shown to be anti-analgesic and lower the pain threshold. ... It does not produce any excitation but has poor analgesic and muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … It is also used for hypnosis and for the control of convulsive states. ... Small doses have been shown to be anti-analgesic and lower the pain threshold. ... It does not produce any excitation but has poor analgesic and muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives …
Gluconolactone
Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder.
Approved
Experimental
Matched Synonyms: … Gluconic acid lactone ... D-gluconic acid delta-lactone …
Matched Description: … It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Matched Description: … It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder. …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids …
Oxfendazole
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester ... (5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. …
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. …
PXL-770 free acid anhydrous
Investigational
Matched Synonyms: … PXL770 free acid anhydrous ... PXL 770 free acid anhydrous …
Matched Name: … PXL-770 free acid anhydrous …
Matched Name: … PXL-770 free acid anhydrous …
Diltiazem
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … Acetic acid (2S,3S)-5-(2-dimethylamino-ethyl)-2-(4-methoxy-phenyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][ ... cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ... -5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate …
Matched Iupac: … 3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and ... Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium-Regulating Hormones and Agents …
Matched Iupac: … 3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate …
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and ... Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Calcium-Regulating Hormones and Agents …
S-oxy-L-cysteine
Experimental
Matched Synonyms: … 3-(oxidosulfanyl)-L-alanine …
Matched Iupac: … (2R)-2-amino-3-sulfinylpropanoic acid …
Matched Iupac: … (2R)-2-amino-3-sulfinylpropanoic acid …
Procyclidine
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Approved
Matched International brands: … Prodine …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
S-Methyl glutathione
Experimental
Matched Synonyms: … L-gamma-Glutamyl-S-methyl-L-cysteinylglycine …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(methylsulfanyl)ethyl]carbamoyl}butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(methylsulfanyl)ethyl]carbamoyl}butanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
2-phospho-D-glyceric acid
A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Experimental
Matched Name: … 2-phospho-D-glyceric acid …
Matched Iupac: … (2R)-3-hydroxy-2-(phosphonooxy)propanoic acid …
Matched Description: … A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration. …
Matched Iupac: … (2R)-3-hydroxy-2-(phosphonooxy)propanoic acid …
Matched Description: … A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration. …
5-phospho-D-arabinohydroxamic acid
Experimental
Matched Name: … 5-phospho-D-arabinohydroxamic acid …
Matched Iupac: … [(2R,3R,4S)-2,3,4-trihydroxy-4-(hydroxycarbamoyl)butoxy]phosphonic acid …
Matched Iupac: … [(2R,3R,4S)-2,3,4-trihydroxy-4-(hydroxycarbamoyl)butoxy]phosphonic acid …
3-hydroxyisoxazole-4-carboxylic acid
Experimental
Matched Name: … 3-hydroxyisoxazole-4-carboxylic acid …
Matched Iupac: … 3-hydroxy-1,2-oxazole-4-carboxylic acid …
Matched Iupac: … 3-hydroxy-1,2-oxazole-4-carboxylic acid …
4,5-Dehydro-D-Glucuronic Acid
Experimental
Matched Name: … 4,5-Dehydro-D-Glucuronic Acid …
Matched Iupac: … (2R,3R,4S)-2,3,4-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … (2R,3R,4S)-2,3,4-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid …
4-(2-Thienyl)Butyric Acid
Experimental
Matched Name: … 4-(2-Thienyl)Butyric Acid …
Matched Iupac: … 4-(thiophen-2-yl)butanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 4-(thiophen-2-yl)butanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Displaying drugs 1751 - 1775 of 2924 in total