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Displaying drugs 1826 - 1850 of 1909 in total

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Synonyms: … Hepatitis B virus hbsag surface protein antigen …
Matched Description: … Certain population subgroups in these areas, however, are at high risk (see Indications and Clinical ... Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses. ... epidemiology vary widely among geographical areas and population subgroups. …
Matched Salts name: … Hepatitis B virus subtype ADW HBSAG surface protein antigen ... Hepatitis B virus subtype ADW2 HBSAG surface protein antigen …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bacterial and viral vaccines, combined ... haemophilus influenzae B and hepatitis B ... Proteins ... Viral Proteins …

Vitex agnus-castus fruit extract

Vitex agnus-castus fruit extract is obtained from dry fruits of Vitex agnus-castus. The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally resemble sex hormones. Clinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast...
Experimental
Matched Description: … The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally ... μ (mu) - and δ (delta) -opioid receptors. ... effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … AGNUCASTON FILM TABLET, 30 ADET …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … inhibiting protein and DNA synthesis. ... As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Onureg 200 mg Film Kaplı Tablet, 7 ADET ... Onureg 300 mg Film Kaplı Tablet, 7 ADET ... Onureg 200 mg Film Kaplı Tablet, 14 ADET …

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … also has both anti-oxidant and anti-inflammatory properties. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and ... Pharmaceuticals and APOTEX have been available since the late 1990s. …
Matched Products: … TRENTAL 400 FILM-COATED TABLET 400 mg ... TRENTAL CR 600 MG FILM KAPLI TABLET, 20 ADET ... TRENTILIN RETARD 600 MG FILM TABLET, 20 ADET …

Ticlopidine

Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot...
Approved
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and ... agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine …
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances ... Sulfur Compounds …
Matched Products: … TICLID FILM COATED TABLET 250MG ... TICLOCARD 250 MG FILM KAPLI TABLET, 30 ADET …

Penbutolol

Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third ... degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. …
Matched Categories: … penbutolol and other diuretics …
Matched Products: … BETAPRESSİN 40 MG FİLM TABLET, 30 TABLET …

Lacidipine

Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia . It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce...
Approved
Investigational
Matched Description: … vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and ... displays a high membrane partition coefficient leading to accumulation of the drug in the membrane and ... antagonists, thiazide diuretics, atenolol (a beta-blocker) and enalapril (an ACE inhibitor) [A31536] …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Channel Blockers ... Selective Calcium Channel Blockers With Mainly Vascular Effects …
Matched Products: … LACIPIL 4 MG FILM TABLET, 14 ADET …

Depelestat

Investigational
Matched Synonyms: … kunitz domain of inter-alpha-trypsin inhibitor light chain: (glu285,ile297,phe300,pro301,arg302)ambp protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …

(5-Hydroxy-6-methyl-4-{[(E)-(3-oxo-1,2-oxazolidin-4-ylidene)amino]methyl}-3-pyridinyl)methyl dihydrogen phosphate

Experimental
Matched Name: … Hydroxy-6-methyl-4-{[(E)-(3-oxo-1,2-oxazolidin-4-ylidene)amino]methyl}-3-pyridinyl)methyl dihydrogen phosphate …

Fidaxomicin

Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Description: … the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and ... bactericidal activity is time-dependent, and not concentration-dependent. ... [A190492] The antibacterial activity of fidaxomicin is distinct from macrolides and rifamycins, as the …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DİFİCLİR 200 MG FİLM KAPLI TABLET, 20 ADET …

Cabotegravir

Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193] Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and …
Matched Salts name: … Cabotegravir sodium …
Matched Products: … Vocabria 30 mg Film Kaplı Tablet, 30 ADET …

Opipramol

Opipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
Investigational
Matched Description: … been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and …
Matched Products: … OPIPRAMOL - CT 50MG FILM ... OPIPRAMOL - CT 100MG FILM …

Rivabazumab pegol

Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN FAB' G1-KAPPA PEGYLATED, ANTI-PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM (TTSS)PCRV PROTEIN …

Copper

Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. Copper is commonly used in contraceptive intrauterine devices (IUD) .
Approved
Investigational
Matched Description: … Copper is a transition metal and a trace element in the body. ... It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and …
Matched Mixtures name: … Calcium With Mg Zn Mn Cu CR Si and Vit. C & D ... Chewable Calcium Plus Magnesium and Minerals ... Protect Plus SO 60 …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Antibacterial PVC film …

Pivmecillinam

Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Description: … It is active against gram-negative organisms and used as for amdinocillin. [PubChem] …
Matched Categories: … Sulfur Compounds …
Matched Products: … Selexid 400 mg film-coated tablets …

Cefaclor

Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Categories: … Sulfur Compounds …
Matched Products: … CECLOR MR 375 MG.10 FILM TB. ... CECLOR MR 750 MG.10 FILM TB. ... SANOCEF 375 MG MR FILM TABLET, 10 TABLET …

Entacapone

Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone …
Matched Products: … Entacapone HEC 200 mg film-coated tablets …

Mycophenolic acid

Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Description: … and antiviral properties. ... to optimize efficacy and minimize toxicity. ... [L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal …
Matched Salts name: … Mycophenolate sodium …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Mycophenolic Acid and Prodrugs …
Matched Products: … MICOSEF 500 MG FILM TABLET, 50 ADET ... CELLCEPT 500 MG FİLM KAPLI TABLET, 50 ADET ... CELLCEPT 500 MG FİLM KAPLI TABLET, 150 ADET …

Cloperastine

Cloperastine is a cough suppressant that acts on the central nervous system.
Experimental
Matched Categories: … Cough and Cold Preparations …
Matched Products: … COPASTIN FILM COATED TABLET 10MG …

Sumatriptan

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched International brands: … Cinie …
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Sulfur Compounds ... Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … İMİGRAN 50 MG FILM KAPLI TABLET, 2 ADET ... İMİGRAN 50 MG FILM KAPLI TABLET, 6 ADET ... İMİGRAN 100 MG FILM KAPLI TABLET, 2 ADET …

Dipyridamole

A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Matched Description: … A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular …
Matched Mixtures name: … Aspirin and Dipyridamole ... Aspirin and Dipyridamole ... Aspirin and Dipyridamole Extended Release …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … DRİSENTİN 75 MG FILM KAPLI TABLET, 50 TABLET ... DRİSENTİN 75 MG FILM KAPLI TABLET, TABLET, 90 ADET …

Zopiclone

Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.
Approved
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Zopiclone and prodrugs ... Sleep Initiation and Maintenance Disorders ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … ZOPICLON-HEXAL 7.5MG FILM ... IMOVANE 7.5 MG FİLM KAPLI TABLET, 5 ADET ... IMOVANE 7.5 MG FİLM KAPLI TABLET, 20 ADET …

Zolpidem

Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Description: … This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases ... It is available in both immediate acting and extended release forms [FDA label], [F3802]. ... according to the manufacturer’s instructions, with a low risk of drug withdrawal, drug dependence, and …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Zodenox Film Coated Tablets 10mg ... REMİN 10 MG FİLM TABLET, 14 ADET ... STILNOX 10MG FILM COATED TABLET …

Albumin human

Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood . It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately...
Approved
Matched Description: … ) and pharmaceuticals (including barbiturates). ... Each domain comprises two separate sub-domains (A and B) [A40060]. ... It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4 …
Matched Mixtures name: … Venomil Wasp Venom Protein (12mcg) ... Venomil Yellow Hornet Venom Protein (12mcg) ... Venomil Yellow Jacket Venom Protein (12mcg) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Substitutes and Plasma Protein Fractions ... Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Plasma Protein Lösung 50 g/l Infusionslösung …

Upadacitinib

Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints. It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage...
Approved
Investigational
Matched Description: … Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic ... and bone destruction, leading to co-morbidities. ... It is characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage damage …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Protein Kinase Inhibitors …
Matched Products: … RINVOQ 15mg Extended Release Film Coated Tablets …
Displaying drugs 1826 - 1850 of 1909 in total