Displaying drugs 1876 - 1900 of 2878 in total
Selegiline
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. …
Matched Salts name: … Selegiline hydrochloride …
Matched Products: … Selegiline Hydrochloride …
Matched Salts name: … Selegiline hydrochloride …
Matched Products: … Selegiline Hydrochloride …
Ticlopidine
Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot...
Approved
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and ... agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine …
Matched Salts name: … Ticlopidine hydrochloride …
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ticlopidine Hydrochloride ... Ticlopidine hydrochloride …
Matched Salts name: … Ticlopidine hydrochloride …
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ticlopidine Hydrochloride ... Ticlopidine hydrochloride …
Naftifine
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Approved
Matched Description: … Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical ... , Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum. ... treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum …
Matched Salts name: … Naftifine Hydrochloride …
Matched Products: … Naftifine Hydrochloride ... Naftifine hydrochloride …
Matched Salts name: … Naftifine Hydrochloride …
Matched Products: … Naftifine Hydrochloride ... Naftifine hydrochloride …
Methysergide
An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...
Approved
Matched Synonyms: … 1-Methyllysergic acid butanolamide ... 1-Methyl-D-lysergic acid butanolamide ... 1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide …
Matched Description: … An ergot derivative that is a congener of lysergic acid diethylamide. ... Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Ergot Alkaloids and Derivatives ... Lysergic Acid …
Matched Description: … An ergot derivative that is a congener of lysergic acid diethylamide. ... Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Categories: … Ergot Alkaloids and Derivatives ... Lysergic Acid …
Nitrofurantoin
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … Nitrofurantoin anhydrous ... Nitrofurantoinum anhydrous …
Matched Description: … cycle as well as synthesis of DNA, RNA, and protein. ... Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid …
Matched Description: … cycle as well as synthesis of DNA, RNA, and protein. ... Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid …
2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid
Experimental
Matched Synonyms: … 5R,6R)-5-Acetamido-4-(diaminomethylideneamino)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Name: … 2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid …
Matched Iupac: … ,6R)-4-[(diaminomethylidene)amino]-5-acetamido-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Name: … 2,4-deoxy-4-guanidino-5-N-acetyl-neuraminic acid …
Matched Iupac: … ,6R)-4-[(diaminomethylidene)amino]-5-acetamido-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
3-nitro-L-tyrosine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
INO-1001
Investigational
Matched Synonyms: … N-(3-Morpholinopropyl)-sulfonyl)-5,6-dihydro-5-oxo-11-H-indeno (1,2-C) isoquinoline methanesulfonic acid …
Matched Iupac: … [3-(morpholin-4-yl)propyl]-5-oxo-5H,6H,11H-indeno[1,2-c]isoquinoline-9-sulfonamide; methanesulfonic acid …
Matched Iupac: … [3-(morpholin-4-yl)propyl]-5-oxo-5H,6H,11H-indeno[1,2-c]isoquinoline-9-sulfonamide; methanesulfonic acid …
Mardepodect
Investigational
Matched Synonyms: … 2-[4-(1-Methyl-4-pyridin-4-yl-lH-pyrazol-3-yl)-phenoxymethyl]-quinoline succinic acid …
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).
Investigational
Matched Synonyms: … 3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)- …
Matched Iupac: … ^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaen-22-yl]propanoic acid …
Matched Iupac: … ^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaen-22-yl]propanoic acid …
WP-1122
WP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.
Investigational
Matched Synonyms: … an acetic acid diester of 2-deoxy-D-glucose …
Fipaxalparant
Investigational
Matched Synonyms: … 1h-indene-2-carboxylic acid, 2,3-dihydro-2-((4-methoxy-3-(2-(3-methylphenyl)ethoxy)benzoyl)amino)- …
Matched Iupac: … 2-{4-methoxy-3-[2-(3-methylphenyl)ethoxy]benzamido}-2,3-dihydro-1H-indene-2-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 2-{4-methoxy-3-[2-(3-methylphenyl)ethoxy]benzamido}-2,3-dihydro-1H-indene-2-carboxylic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
VO659
VO659 is an antisense oligonucleotide being investigated for the treatment of Huntington's disease.
Investigational
Matched Synonyms: … antisense oligonucleotide that has been developed to target expanded CAG repeats in messenger ribonucleic acid …
Green tea leaf
Green tea leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Camelliae Folium ... Camelliae Sinensis Folium ... Camelliae Sinensis Non Fermentatum Folium …
Matched Categories: … Diet, Food, and Nutrition …
Matched Categories: … Diet, Food, and Nutrition …
Trazpiroben
Investigational
Matched Synonyms: … (3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8 triazaspiro(4.5) decan-3-yl)methyl)benzoic acid ... Benzoic acid, 3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro(4.5)dec-3-yl)methyl)- …
Epicaptopril
Experimental
Matched Synonyms: … (2S)-1-((2R)-2-Methyl-3-sulfanylpropanoyl)pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Matched Iupac: … (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
RU82197
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid …
Matched Iupac: … (3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic acid …
Matched Iupac: … (3S)-1-({[1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-formylbenzoic acid …
Cyclobenzaprine
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Des(carbamimidoyl) zanamivir
Experimental
Matched Synonyms: … 4-Amino-2-deoxy-2,3-dehydro-N-neuraminic acid …
Matched Iupac: … (2R,3R,4S)-4-amino-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … (2R,3R,4S)-4-amino-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Naproxcinod
Investigational
Matched Synonyms: … (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester …
Matched Categories: … Naphthaleneacetic Acids ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Categories: … Naphthaleneacetic Acids ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Ethyl salicylate
Approved
Experimental
Matched Synonyms: … Salicyclic acid, ethyl ester …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
PIK-75
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
APD-209
Investigational
Matched Synonyms: … -neuraminic acid, n-acetyl-2-o-(7,26-dioxo-10,13,16,19,22-pentaoxa-6,25-diazapentaconta-35,37-diyn-1- …
Displaying drugs 1876 - 1900 of 2878 in total