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Displaying drugs 176 - 200 of 10979 in total
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Synonyms: … adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate] ... Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine ... Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid ... 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Synonyms: … bis(4-hydroxycoumarin-3-yl)methane ... di-(4-hydroxy-3-coumarinyl)methane …
Matched Iupac: … 4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one …
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Synonyms: … (R)-Carnitine ... 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt …
Matched Iupac: … (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate …
Matched Products: … ALMİBA 1G/5 ML İM/IV ENJEKSİYONLUK ÇÖZELTİ,5 ADET ... CARNIA 1 G/5 ML ENJEKTABL ÇÖZELTİ İÇEREN AMPUL, 5 ADET ... LEKARNITIN 1 G/5 ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 5 ADET …
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
Approved
Investigational
Matched Synonyms: … (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl ... }-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7S)-7-{2-[(cyanomethyl)sulfanyl]acetamido}-7-methoxy-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl ... ]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Salts cas: … 56796-39-5
Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium …
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid technetium …
Approved
Illicit
Matched Synonyms: … 17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate …
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … (2S)-2-amino-3-carbamoylpropanoic acid ... (S)-2-amino-3-carbamoylpropanoic acid …
Matched Iupac: … (2S)-2-amino-3-carbamoylpropanoic acid …
Matched Mixtures name: … AMINOPLASMAL-5% E INFUSION …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Synonyms: … 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine ... 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine ... N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Mixtures name: … Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
An antiandrogen with about the same potency as cyproterone in rodent and canine species.
Approved
Investigational
Matched Synonyms: … 4'-nitro-3'-trifluoromethylisobutyranilide …
Matched Iupac: … 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide …
Flutemetamol (18F) is a PET scanning radiopharmaceutical containing the radionuclide fluorine-18. It is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) or other causes of cognitive decline.
Approved
Investigational
Matched Synonyms: … 2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
Matched Iupac: … 2-[3-(¹⁸F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol …
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … )-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3- ... TRIMETHYL-1,4,7,11,14-PENTAOXO-1H-PYRROLO(2,1-I)(1,4,7,10,13)OXATETRAAZACYCLOHEXADECIN-10-YL)-4,6-DIMETHYL-3- ... N,N'-((2-AMINO-4,6-DIMETHYL-3-OXO-3H-PHENOXAZINE-1,9-DIYL)-BIS(CARBONYLIMINO(2-HYDROXYPROPYLIDENE)CARBONYLIMINOISOBUTYLIDENECARBONYL …
Matched Iupac: … )-hexadecahydro-1H-pyrrolo[2,1-i]1-oxa-4,7,10,13-tetraazacyclohexadecan-10-yl]-2-amino-4,6-dimethyl-3- …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine ... 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine ... L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine …
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Mixtures name: … DELMUNO 5/5 MG ... TRIAPIN 5/5MG ... DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADET …
Matched Products: … ฟีโลปีน 5 ... MODIP 5 MG ... FEDIL SR TABLETS 5 MG …
Sulfaphenazole is a sulfonamide antibacterial.
Approved
Matched Synonyms: … 3-(p-aminobenzenesulfonamido)-2-phenylpyrazole ... 1-phenyl-5-sulfanilamidopyrazole ... 5-sulfanilamido-1-phenylpyrazole …
Matched Iupac: … 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide …
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … -1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3- …
Matched Iupac: … 7aS)-octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3- …
Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Synonyms: … Granulocyte colony stimulating factor 3 (CHO cell derived) …
Acer saccharum pollen is the pollen of the Acer saccharum plant. Acer saccharum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 3 Maple Pollen Mix ... 3 Maple Pollen Mix ... 3 Maple Pollen Mix …
Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Synonyms: … Human herpesvirus 3 immune globulin …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid …
Matched Mixtures name: … MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 30 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 50 G …
Matched Products: … MAJEZIK %5 TOPIKAL JEL, 30 G ... MAJEZIK %5 TOPIKAL JEL, 50 G ... MAJEZIK % 5 TOPIKAL SPREY, ÇÖZELTİ, 50 ML …
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid …
Matched Mixtures name: … ทวินสตา 40/5 มก. ... ทวินสตา 80/5 มก. ... CARDIOCAPA 40/5
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo …
Matched Mixtures name: … AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 60 KPS ... AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 120 KPS ... AIRBIR 3/200 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL ,60 KAPSÜL …
Matched Products: … ENTOCORT(R)2 MG ... RHINOCORT (R) AQUA 64 MCG/DOSIS ... BUDENOFALK 3 MG CAPSULE …
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Salts cas: … 64-75-5
Matched Products: … แอ็คนิซิน ที5 แค็ปซูล ... Tetra Now 3% ... NOACNE %3 MERHEM …
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … 4-{(E)-2-[6-(2-{2-[2-(18F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl}-N-methylaniline …
Matched Iupac: … 4-[(E)-2-[6-(2-{2-[2-(¹⁸F)fluoroethoxy]ethoxy}ethoxy)pyridin-3-yl]ethenyl]-N-methylaniline …
Displaying drugs 176 - 200 of 10979 in total