Displaying drugs 176 - 200 of 806 in total
Tetracosactide
Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Synonyms: … adrenocorticotropic hormone 1-24 ... Adrenocorticotropic hormone fragment 1-24 human, rat …
Matched Description: … 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Adrenocorticotropic Hormone …
Matched Description: … 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Adrenocorticotropic Hormone …
Follitropin
Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Synonyms: … Follicle stimulating hormone ... Recombinant human follicle stimulating hormone beta ... Recombinant human follicle-stimulating hormone (r-HFSH) …
Matched Description: … Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which ... stimulating hormone (FSH). ... analysis shows that the amino acid sequence of follitropin beta is identical to that of natural human follicle …
Matched Categories: … Follicle Stimulating Hormone ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which ... stimulating hormone (FSH). ... analysis shows that the amino acid sequence of follitropin beta is identical to that of natural human follicle …
Matched Categories: … Follicle Stimulating Hormone ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Erythropoiesis stimulating factor …
Matched Description: … Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using …
Matched Categories: … Colony-Stimulating Factors ... Erythropoiesis-Stimulating Agents …
Matched Description: … Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using …
Matched Categories: … Colony-Stimulating Factors ... Erythropoiesis-Stimulating Agents …
Esterified estrogens
Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of...
Approved
Quinestrol
The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Diethylstilbestrol
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Estradiol dienanthate
Estradiol Dienanthate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … Estradiol Dienanthate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates ... Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Synthetic Conjugated Estrogens, A
Synthetic conjugated estrogens A are composed of a blend of the following nine synthetic estrogenic substances: estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, and sodium 17β-estradiol sulfate. This blend of nine estrogen derivatives...
Approved
Matched Description: … (LH) and follicle stimulating hormone (FSH) through a negative feedback mechanism. ... Prior to menopause, the primary source of estrogen is the ovarian follicle, which secretes 70-500 micrograms ... This shift in hormone production is largely responsible for many of the symptoms experienced during and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Synthetic Conjugated Estrogens, B
Synthetic conjugated estrogens, B tablets contain a blend of ten synthetic estrogenic substances. The estrogenic substances are: sodium estrone sulfate, sodium equilin sulfate, sodium 17α-dihydroequilin sulfate, sodium 17α-estradiol sulfate, sodium 17β dihydroequilin sulfate, sodium 17α-dihydroequilenin sulfate, sodium 17β-dihydroequilenin sulfate, sodium equilenin sulfate, sodium 17β-estradiol sulfate, and sodium Δ8,9-dehydroestrone sulfate. This...
Approved
Matched Description: … (LH) and follicle stimulating hormone (FSH) through a negative feedback mechanism. ... Prior to menopause, the primary source of estrogen is the ovarian follicle, which secretes 70-500 micrograms ... This shift in hormone production is largely responsible for many of the symptoms experienced during and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Conjugated estrogens
The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.[L5605,...
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Castor oil
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Mixtures name: … Hair Follicle Massage Kit …
Danazol
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormone Antagonists …
Desogestrel
Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Ulipristal
Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. It also binds to glucocorticoid receptor, however compared to...
Approved
Norethisterone
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19 ... or in combination with estrogen derivatives in a variety of applications including contraception and hormone …
Efbemalenograstim alfa
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Description: … Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating …
Matched Categories: … Colony-Stimulating Factors ... Granulocyte Colony-Stimulating Factors …
Matched Categories: … Colony-Stimulating Factors ... Granulocyte Colony-Stimulating Factors …
Afamelanotide
Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating hormone (α-MSH). It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer biological half-life.[A187202,A187205] Afamelanotide is...
Approved
Investigational
Matched Description: … hormone (α-MSH). ... Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating …
Matched Categories: … Melanocyte-Stimulating Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Melanocyte-Stimulating Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Somatrem
Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents continues to be mired in persistent bioethical debate . Such discussion revolves around whether patients' natural disposition of short...
Approved
Investigational
Withdrawn
Matched Description: … children with or without growth hormone deficiency [A32292]. ... therapy - especially when these hormone agents have been proven effective at increasing the height of ... disposition of short stature should be considered a medical condition justifying medical treatment with such hormone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Growth Hormone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Growth Hormone …
Darbepoetin alfa
Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Approved
Investigational
Matched Categories: … Colony-Stimulating Factors ... Erythropoiesis-Stimulating Agents …
Lorcaserin
Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is...
Approved
Withdrawn
Plerixafor
Plerixafor is a small-molecule inhibitor of C-X-C chemokine receptor type 4 (CXCR4) that acts as a hematopoietic stem cell mobilizer.[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune...
Approved
Investigational
Medrysone
Medrysone is a corticosteroid used in ophthalmology.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Corticosteroid Hormone Receptor Agonists …
Prednisolone tebutate
Approved
Vet approved
Cholecystokinin
Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Description: … which is responsible for stimulating the digestion of fat and protein. ... Soon after, it was recognized to be identical to the factor responsible for stimulating pancreatic exocrine ... Cholecystokinin ( also known as _CCK or CCK-PZ_) is a peptide hormone of the gastrointestinal system …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Insulin human
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Description: … Typically prescribed for the management of diabetes mellitus, insulin is a peptide hormone produced by ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Displaying drugs 176 - 200 of 806 in total