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Displaying drugs 176 - 200 of 9230 in total

Bisoprolol

Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Products: … B-BETA …

Triclosan

An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … group. ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy …
Matched Products: … Dermaprot Triclotrex-B ... Triclotrex-B Antibacterial ... Triclotrex-B Antibacterial (neutral) …

Ibritumomab tiuxetan

Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and...
Approved
Investigational
Matched Description: … which is found on the surface of normal and malignant B lymphocytes. ... Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, …
Matched Categories: … Lymphoma, B-Cell …

Lidocaine

Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Mixtures name: … B-VIT HT ... B-VIT HT ... VOTRIPAX B+L …
Matched Categories: … Membrane Transport Modulators …
Matched Products: … No-AD Aloe Vera Gel 98% Pure ... Inkeeze Original B Numb ... Inkeeze Original B Numb Cylinder …

Mosunetuzumab

Mosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody. It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells. The standard of care for patients with B-cell lymphoma includes an anti-CD20 monoclonal antibody, such as...
Approved
Investigational
Matched Description: … [L42230] It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 ... leukemia (CLL) or aggressive B-cell lymphoma, have a high probability of relapse or recurrence after ... [A249320] The standard of care for patients with B-cell lymphoma includes an anti-CD20 monoclonal antibody …

Rituximab

Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen ... found on the surface of normal and malignant B lymphocytes. ... FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however …

Davesomeran

Davesomeran is a mRNA vaccine used in conjunction with elasomeran as part of the Moderna Bivalent COVID-19 vaccine. Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion stabilized spike (S) protein to elicit an immune response.[L43882,L28026] However, with the addition of davesomeran, Moderna Bivalent vaccine...
Approved
Investigational
Matched Description: … stabilized spike (S) protein to elicit an immune response. ... Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion ... and the BA.4/5 strain compared to that of the Moderna COVID-19 Vaccine. …

Brompheniramine

Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Mixtures name: … Bio T Pres-B ... Entre-B ... Altipres-B …

Tenofovir alafenamide

Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Description: … [A178060] Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir ... [A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388, …
Matched Categories: … Vitamin B Complex ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor …

Buserelin

Buserelin is a synthetic peptide analog of the luteinizing hormone-releasing hormone (LHRH) agonist, which stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR). It is used in prostate cancer treatment.
Approved
Investigational

Candicidin

Candicidin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.
Approved
Withdrawn

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Products: … REMIFENTANIL B. BRAUN …

Bretylium

Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Products: … LOPEDIUM AKUT B AKU DURCHF ... LOPEDIUM T AKUT B AK DURCH …

Levofloxacin

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Products: … LEVOFLOXACINA B. BRAUN …

Bleomycin

A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational

Isoxaflutole

Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder.
Approved
Experimental
Investigational
Matched Description: … Balance has been investigated for the treatment of Chronic Renal Failure and Peritoneal Membrane Disorder …
Matched Categories: … Membrane Proteins …

Allantoin

Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Mixtures name: … Botaneth Pronoxin Hair Regainer Fs2 Activator 2-A 2-B ... Botaneth Pronoxin Hair Regainer Fs2 Activator 2-A 2-B …
Matched Products: … Burn-B Gone OTC ... Shelo NABEL D B T Cream …

Methylene blue

Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Matched Description: … Aberdeen and TauRx Therapeutics that has been shown in early clinical trials to be an inhibitor of Tau protein …
Matched Mixtures name: … UroAv-B ... UroAv-B …

Flotufolastat F-18

Flotufolastat F-18 (18F-rhPSMA-7.3) is an 18F-labeled ligand that targets the prostate-specific membrane antigen (PSMA).[A259846,L46731] In patients with recurrent prostate cancer that require localized treatment, the use of 18F-labeled ligands for positron emission tomography (PET) offers accurate diagnostic imaging. Unlike 68Ga-labeled PSMA-targeting ligands, 18F-labeled compounds targeting this protein have a longer...
Approved
Investigational
Matched Description: … antigen (PSMA). ... (18F-rhPSMA-7.3) is an 18F-labeled ligand that targets the prostate-specific membrane ... Unlike 68Ga-labeled PSMA-targeting ligands, 18F-labeled compounds targeting this protein …

Teclistamab

Teclistamab is an IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. Teclistamab consists of an anti-BCMA arm and an anti-CD3 arm connected via two interchain disulfide bonds,[A253587, L43622] allowing the drug...
Approved
Investigational
Matched Description: … cell maturation antigen (BCMA) expressed on malignant multiple myeloma cells. ... IgG4-PAA bispecific antibody that targets the CD3 receptor expressed on the surface of T cells and B …
Matched Categories: … Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …

Glofitamab

Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488] Glofitamab was approved...
Approved
Investigational
Matched Description: … full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- ... Canada in March 2023 for the treatment of certain patients with relapsed or refractory diffuse large B-cell ... CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells …

Zanubrutinib

Zanubrutinib is a novel Bruton's tyrosine kinase (BTK) inhibitor used for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Mantle cell lymphoma is an aggressive mature B-cell non-Hodgkin lymphoma associated with early relapse, poor clinical outcomes, and long-term survival. BTK...
Approved
Investigational
Matched Description: … enhanced selectivity towards BTK, zanubrutinib belongs to the second-generation BTK inhibitor drug group ... [L10163] Mantle cell lymphoma is an aggressive mature B-cell non-Hodgkin lymphoma associated with early ... plays a role in oncogenic signalling pathways, promoting the survival and proliferation of malignant B …
Matched Categories: … Protein Kinase Inhibitors …

Chlorpheniramine

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Salts cas: … 56343-98-7 …
Matched Mixtures name: … DAYFLU B ... Bio-B Kids …
Matched Products: … Truemed Group LLC …

Besifloxacin

Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Approved
Displaying drugs 176 - 200 of 9230 in total