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Displaying drugs 2026 - 2050 of 15207 in total

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... by inhibiting glucose reabsorption in the proximal tubule of the nephron and causing glycosuria. ... [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control …
Matched Mixtures name: … Dapagliflozin and Metformin Hydrochloride ... Dapagliflozin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and dapagliflozin ... saxagliptin and dapagliflozin ... sitagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …

Xylose

Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group. Xylose is a sugar isolated from wood. D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage. Xylose has also been used as a diagnostic agent to observe...
Approved
Matched Description: … D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage. ... Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional ... immediately - but its metabolism results in a variety of substrates that can serve important nutritional and …

Zonisamide

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Quinupristin

Quinupristin/dalfopristin is a combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis. The combination of the two components acts synergistically and is more...
Approved
Matched Description: … Quinupristin/dalfopristin is a combination of two antibiotics used to treat infections by staphylococci and ... Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin ... The combination of the two components acts synergistically and is more effective in vitro than each component …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Escitalopram

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …

Voclosporin

Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed with SLE, 5-20% of those suffering from LN develop end-stage kidney disease, a...
Approved
Investigational
Matched Description: … Early and accurate intervention for LN is important in improving clinical outcomes. ... LN is a significant cause of renal failure, morbidity, and death in patients with SLE. ... [L31208] Voclosporin has demonstrated a more stable pharmacokinetic and pharmacodynamic relationship …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Mebeverine

Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Approved
Investigational
Matched Description: … Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy …
Matched Categories: … Alimentary Tract and Metabolism …

Atogepant

Atogepant is an oral antagonist of calcitonin gene-related peptide (CGRP) receptors indicated for the prevention of episodic migraine headaches. It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021. While its approval was predated by two other members of the same drug family,...
Approved
Investigational
Matched Description: … [valproic acid] or [topiramate]) or beta-blockers (e.g. ... It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021. ... ] While its approval was predated by two other members of the same drug family, namely [ubrogepant] and …

Strontium chloride Sr-89

Strontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate cancer. Bone metastases is a common and severe complication presented in advanced stages of the disease. It...
Approved
Investigational
Matched Description: … lung, bladder and thyroid. ... It is usually presented mainly in patients with prostatic and breast cancer, as well as in cancer of ... [A31264] Bone metastases is a common and severe complication presented in advanced stages of the disease …

Asunaprevir

Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on...
Approved
Investigational
Withdrawn
Matched Description: … [A32528] It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on April 22, 2016 …
Matched Categories: … daclatasvir, asunaprevir and beclabuvir …

DL-dimyristoylphosphatidylglycerol

DL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Approved
Matched Iupac: … [2,3-bis(tetradecanoyloxy)propoxy](2,3-dihydroxypropoxy)phosphinic acid …

Pilocarpine

A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Description: … intraocular pressure and glaucoma. ... [A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated …
Matched Categories: … Antiglaucoma Preparations and Miotics …

Anastrozole

Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such...
Approved
Investigational
Matched Description: … provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and ... drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Oxandrolone

A synthetic hormone with anabolic and androgenic properties.
Approved
Investigational
Matched Description: … A synthetic hormone with anabolic and androgenic properties. …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Polydatin

Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. ... in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and …

Prazosin

Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress...
Approved
Matched Description: … Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. ... evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and …
Matched Categories: … prazosin and diuretics ... Alpha-Adrenoreceptor Antagonists and Diuretics …

Cavia porcellus skin

Cavia porcellus skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Guinea Pig Hair and Epithelia …

Tetraferric tricitrate decahydrate

Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.
Approved
Matched Description: … Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and …
Matched Mixtures name: … Maxine Vitamin and Mineral Supplement …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Sus scrofa hair

Wild boar hair is used in allergenic testing.
Approved
Matched Mixtures name: … Hog Hair and Epithelia …

Lime (citrus)

Lime (citrus) allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … SEED Teatree and Lime Vegan No-sebum Cool Anti HairlossShampoo …

Salix alba bark

Salix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Mixtures name: … Herbal Cold and Flu Formula - Tab …
Matched Categories: … Herbs and Natural Products …

Oryctolagus cuniculus hair

European rabbit hair is used in allergenic testing.
Approved
Matched Mixtures name: … Rabbit Hair and Epithelia …

Voxilaprevir

Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … mature virus: NS3, NS4A, NS4B, NS5A, and NS5B [A19643]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... genetic material into the following structural and nonstructural proteins required for assembly into …
Matched Categories: … Amino Acids, Peptides, and Proteins ... sofosbuvir, velpatasvir and voxilaprevir …

Fulvestrant

Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. While it is used as monotherapy for the...
Approved
Investigational
Matched Description: … It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Tritoqualine

Approved
Matched Categories: … Cholagogues and Choleretics …
Displaying drugs 2026 - 2050 of 15207 in total