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Displaying drugs 2051 - 2075 of 6785 in total
PR006
PR006 is a non-replicating recombinant adeno-associated virus serotype 9 containing the progranulin gene. It is being investigated for the treatment of dementia.
Investigational
Matched Description: … PR006 is a non-replicating recombinant adeno-associated virus serotype 9 containing the progranulin gene …
ACTX-401
ACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human immunoglobulin u-binding protein 2 cDNA.
Investigational
Matched Description: … ACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing …
Technetium Tc-99m
Technetium-99m is the metastable isotope of technetium. It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.
Experimental
Icotinib
Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)
Icotinib was approved in China by the SFDA in June, 2011 and in January 2014, Beta Pharma, Inc. was given a “May Proceed” from the US FDA to conduct a Phase I study for the...
Experimental
Investigational
Matched Iupac: … N-(3-ethynylphenyl)-7H,8H,10H,11H,13H,14H-1,4,7,10-tetraoxacyclododeca[2,3-g]quinazolin-4-amine …
Trifluoro-thiamin phosphate
Experimental
Matched Iupac: … 3-{[4-amino-2-(trifluoromethyl)pyrimidin-5-yl]methyl}-4-methyl-5-[2-(phosphonatooxy)ethyl]-1,3-thiazol …
L-377202
L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).
Investigational
Matched Synonyms: … 5-((2s,4r)-2-(((1s)-2-(((1s)-2-(((1s)-2-(((1s)-4-amino-1-(((1s)-1-(hydroxymethyl)-2-(((1s)-1-(((2s,3s ... 5,12-NAPHTHACENEDIONE, 10-((3-(((4R)-1-(4-CARBOXY-1-OXOBUTYL)-4-HYDROXY-L-PROLYL-L-ALANYL-L-SERYL-(2S ... trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1h-tetracen-1-yl)oxy)tetrahydropyran-4- …
SB 224289
SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.
Investigational
Matched Synonyms: … 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-yl)carbonyl)spiro ... Spiro(2h-furo(2,3-f)indole-3(5h),4'-piperidine), 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4 ... (1'-methyl-6,7-dihydro-5h-spiro(furo(2,3-f)indole-3,4'-piperidin)-5-yl)(2'-methyl-4'-(5-methyl-1,2,4- …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro …
Matched Description: … SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122] …
Matched Iupac: … 1'-methyl-5-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-carbonyl]-2,5,6,7-tetrahydrospiro …
Matched Description: … SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122] …
L-Rhamnitol
Experimental
Genistein
An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines.
Additionally, genistein has antihelmintic activity. It has been...
Investigational
Matched Synonyms: … 5,7-dihydroxy-3-(4-hydroxyphenyl)-chromen-4-one ... 4H-1-BENZOPYRAN-4-ONE, 5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)- ... 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one …
Matched Iupac: … 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one …
Matched Iupac: … 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one …
4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose
Experimental
Matched Synonyms: … 1,4-Deoxy-4-((5-Hydroxymethyl-2,3,4-Trihydroxycyclohex-5-Enyl)Amino)Fructose ... 4,6-Dideoxy-4-{[(1s,5r,6s)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-d-xylo-hex-5-enopyranose …
Matched Name: … 4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose …
Matched Iupac: … (3S,4S,5R)-4,5-dihydroxy-6-oxo-3-{[(3S,4S,5R,6S)-4,5,6-trihydroxy-2-methylideneoxan-3-yl]amino}cyclohex …
Matched Name: … 4,6-Dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxo-2-cyclohexen-1-yl]amino}-α-D-xylo-hex-5-enopyranose …
Matched Iupac: … (3S,4S,5R)-4,5-dihydroxy-6-oxo-3-{[(3S,4S,5R,6S)-4,5,6-trihydroxy-2-methylideneoxan-3-yl]amino}cyclohex …
Umirolimus
Experimental
Matched Iupac: … (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-12-[(2R)-1-[(1S,3R,4R)-4-(2-ethoxyethoxy) ... methoxycyclohexyl]propan-2-yl]-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4- …
CPZEN-45
Investigational
Matched Synonyms: … -d-ribofuranosyl)-5'-c-((2s)-5-(((4-butylphenyl)amino)carbonyl)-2,3,4,7-tetrahydro-1,4-dimethyl-3-oxo ... -2-yl]methyl}-N-(4-butylphenyl)-4,7-dimethyl-6-oxocyclohept-1-ene-1-carboxamide ... Uridine, 5'-o-(5-amino-5-deoxy-.beta. …
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo ... (2S)-2-[(S)-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}[(2S,3S,4R,5R)-5-(2,4-dioxo- ... -2,3,4,7-tetrahydro-1H-1,4-diazepine-5-carboxamide …
Matched Iupac: … 1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo ... (2S)-2-[(S)-{[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy}[(2S,3S,4R,5R)-5-(2,4-dioxo- ... -2,3,4,7-tetrahydro-1H-1,4-diazepine-5-carboxamide …
Temuterkib
Investigational
Matched Synonyms: … )-5-(2-(4-morpholinyl)ethyl)- ... 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl)-5-(2-(4-morpholinyl)ethyl ... 4h-thieno(2,3-c)pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl …
Rotenone
Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.
Vet approved
Matched Synonyms: … 5'β-rotenone …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
STX-107
Investigational
Matched Synonyms: … 3-Fluoro-5-(5-((2-methylthiazol-4-yl)ethynyl)pyridin-2-yl)benzonitrile ... 3-fluoro-5-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-2-yl]benzonitrile …
Matched Iupac: … 3-fluoro-5-{5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-2-yl}benzonitrile …
Matched Iupac: … 3-fluoro-5-{5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-2-yl}benzonitrile …
Artefenomel
Artefenomel has been investigated for the treatment of Malaria.
Investigational
Matched Iupac: … 4-(2-{4-[(4's,4''s)-dispiro[adamantane-2,2'-[1,3,5]trioxolane-4',1''-cyclohexane]-4''-yl]phenoxy}ethyl …
Matched Salts cas: … 1029939-87-4 …
Matched Salts cas: … 1029939-87-4 …
North-methanocarbathymidine
Investigational
Matched Synonyms: … .,2.alpha.,4.beta.,5.alpha ... 1-((1s,2s,4s,5r)-4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl-2,4(1h,3h)-pyrimidinedione ... 2,4(1h,3h)-pyrimidinedione, 1-((1s,2s,4s,5r)-4-hydroxy-5-(hydroxymethyl)bicyclo(3.1.0)hex-2-yl)-5-methyl …
Matched Iupac: … 1-[(1S,2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)bicyclo[3.1.0]hexan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine …
Matched Iupac: … 1-[(1S,2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)bicyclo[3.1.0]hexan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine …
Dimericine
Investigational
Grapiprant
Grapiprant, also known as AT-001 and CJ-023, is a drug from the piprant class. These molecules were derived from acylsulfonamide and are characterized to be a novel series of para-N-acylaminomethylbenzoic acid known to be prostaglandin receptor antagonists. This type of molecules is currently in development for veterinary patients. This class...
Investigational
Vet approved
Matched Iupac: … 3-[2-(4-{2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl}phenyl)ethyl]-1-(4-methylbenzenesulfonyl) …
Afegostat
Experimental
Investigational
Matched Synonyms: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Matched Iupac: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Matched Iupac: … (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol …
Tetraiodothyroacetic acid
Experimental
Matched Synonyms: … 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid ... ACETIC ACID, (4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3,5-DIIODOPHENYL)- …
Matched Iupac: … 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid …
Matched Iupac: … 2-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic acid …
GS-100
GS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression cassette containing the human NGLY1 gene coding sequence
Investigational
Matched Description: … GS-100 is an adeno-associated virus serotype 9 virus particle containing viral DNA that includes an expression …
Displaying drugs 2051 - 2075 of 6785 in total