Displaying drugs 2101 - 2125 of 2754 in total
Ziltivekimab
Ziltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).
Investigational
Matched Synonyms: … Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Elvitegravir
Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Because integrase is necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and thereby blocks the formation of the...
Approved
Matched Synonyms: … fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and ... thereby blocks the formation of the HIV-1 provirus and resulting propagation of the viral infection. ... Elvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. …
Matched Categories: … emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat …
Matched Iupac: … fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and ... thereby blocks the formation of the HIV-1 provirus and resulting propagation of the viral infection. ... Elvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. …
Matched Categories: … emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat ... emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat …
Memantine
Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Memantine hydrochloride …
Matched Categories: … donepezil, memantine and Ginkgo folium ... Excitatory Amino Acid Antagonists ... donepezil and memantine …
Matched Products: … Memantine Hydrochloride ... Memantine hydrochloride ... Mematine Hydrochloride …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Memantine hydrochloride …
Matched Categories: … donepezil, memantine and Ginkgo folium ... Excitatory Amino Acid Antagonists ... donepezil and memantine …
Matched Products: … Memantine Hydrochloride ... Memantine hydrochloride ... Mematine Hydrochloride …
EP-0042
Investigational
Matched Synonyms: … 3H-IMIDAZO(4,5-B)PYRIDINE, 6-CHLORO-7-(4-((4-CHLOROPHENYL)METHYL)-1-PIPERAZINYL)-2-(1,3-DIMETHYL-1H-PYRAZOL …
Matched Salts name: … EP-0042 fumarate …
Matched Salts name: … EP-0042 fumarate …
Idasanutlin
Idasanutlin has been used in trials studying the treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and Neoplasms, Leukemia, Acute Myeloid Leukemia.
Investigational
Matched Synonyms: … BENZOIC ACID, 4-((((2R,3S,4R,5S)-3-(3-CHLORO-2-FLUOROPHENYL)-4-(4-CHLORO-2-FLUOROPHENYL)-4-CYANO-5-(2,2 …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-amido]-3-methoxybenzoic acid …
Matched Description: … treatment of Neoplasms, Non-Hodgkin's Lymphoma, Leukemia, Myeloid, Acute, Recurrent Plasma Cell Myeloma, and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Cefamandole
Cefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, cefamandole nafate. It is no longer marketed in the United States.
Approved
Experimental
Matched Synonyms: … Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-carboxylic acid ... [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Thiazines …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Thiazines …
CTS-1027
CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.
Experimental
Investigational
Matched Synonyms: … 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL )-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE ... 4-(4-(4-CHLORO-PHENOXY)-BENZENESULFONYLMETHYL)-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HYDROXYAMIDE …
Matched Description: … CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Description: … CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Albendazole
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Synonyms: … (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … LISIPAR BIOLINE TABLETAS. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … LISIPAR BIOLINE TABLETAS. …
S-sulphocysteine
Experimental
Matched Synonyms: … Cysteinyl-S-sulfonic acid …
Matched Iupac: … (2R)-2-amino-3-(sulfosulfanyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Iupac: … (2R)-2-amino-3-(sulfosulfanyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Moxonidine
Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive. As well, moxonidine has been shown...
Approved
Investigational
Matched Synonyms: … [[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid …
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and ... calcium channel blockers are not appropriate or irresponsive. …
Matched Salts name: … Moxonidine hydrochloride …
Matched Categories: … moxonidine and diuretics …
Matched Description: … suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and ... calcium channel blockers are not appropriate or irresponsive. …
Matched Salts name: … Moxonidine hydrochloride …
Matched Categories: … moxonidine and diuretics …
Vodudeutentan
Investigational
Matched Synonyms: … BQ-788 free acid, di(methyl-d)- …
Matched Iupac: … -carbonyl]amino}-4,4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid …
Matched Iupac: … -carbonyl]amino}-4,4-dimethylpentanamido]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoic acid …
EA-230
EA-230 is under investigation in clinical trial NCT03145220 (Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)).
Investigational
Matched Synonyms: … (2S)-5-AMINO-2-(((2S)-2-AMINOPROPANOYL)AMINO)-5-OXO-PENTANOYL)AMINO)ACETYL)AMINO)-3-METHYL-BUTANOIC ACID …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Finafloxacin
Finafloxacin is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December 2014.
Approved
Investigational
Matched Synonyms: … fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid …
Matched Iupac: … octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and ... Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December …
Matched Salts name: … finafloxacin hydrochloride …
Matched Iupac: … octahydropyrrolo[3,4-b]morpholin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and ... Finafloxacin is marketed by Novartis under the brand Xtoro™, and was approved by the FDA in December …
Matched Salts name: … finafloxacin hydrochloride …
Gemcitabine
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … gemcitabine is transformed into its active metabolites that work by replacing the building blocks of nucleic acids ... Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [L32950] It is also being investigated in other cancer and tumour types. …
Matched Salts name: … Gemcitabine hydrochloride …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Gemcitabine Hydrochloride ... Gemcitabine hydrochloride ... GEMCITABINE HYDROCHLORIDE …
Matched Salts name: … Gemcitabine hydrochloride …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Gemcitabine Hydrochloride ... Gemcitabine hydrochloride ... GEMCITABINE HYDROCHLORIDE …
Sodium phosphate, monobasic
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Synonyms: … Sodium acid phosphate ... Phosphoric acid, monosodium salt, anhydrous …
Matched Mixtures name: … Ionosol and Dextrose ... Monobasic Sodium Phosphate and Dibasic Sodium Phosphate ... Ionosol B and Dextrose …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids ... Acids, Noncarboxylic …
Matched Mixtures name: … Ionosol and Dextrose ... Monobasic Sodium Phosphate and Dibasic Sodium Phosphate ... Ionosol B and Dextrose …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids ... Acids, Noncarboxylic …
Izaflortaucipir
Investigational
Matched Synonyms: … 9h-pyrido(3',4':4,5)pyrrolo(2,3-b)pyridine, 2-(2-fluoro-4-pyridinyl)- …
Thieno[2,3-B]Pyridine-2-Carboxamidine
Experimental
Matched Name: … Thieno[2,3-B]Pyridine-2-Carboxamidine …
Navtemadlin
Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia).
Investigational
Matched Synonyms: … chlorophenyl)-3-methyl-1-[ (2S)-3 -methyl-1-(propan-2- ylsulfonyl)butan-2-yl]-2-oxopiperidin-3-yl}acetic acid …
Matched Iupac: … chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-(propane-2-sulfonyl)butan-2-yl]-2-oxopiperidin-3-yl]acetic acid …
Matched Description: … Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-(propane-2-sulfonyl)butan-2-yl]-2-oxopiperidin-3-yl]acetic acid …
Matched Description: … Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Amlitelimab
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Synonyms: … Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005- …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Matched Description: … Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and ... Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Salts name: … Ofloxacin hydrochloride …
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Salts name: … Ofloxacin hydrochloride …
Matched Categories: … ofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances …
(2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid
Experimental
Matched Name: … -4-carboxylic acid ... -1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine …
Matched Iupac: … -4-carboxylic acid ... -(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine …
Matched Iupac: … -4-carboxylic acid ... -(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine …
Ceftibuten
Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered. It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Approved
Investigational
Matched Synonyms: … -(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid …
Matched Iupac: … amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and …
Matched Categories: … Thiazines …
Matched Iupac: … amino-1,3-thiazol-4-yl)-4-carboxybut-2-enamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and …
Matched Categories: … Thiazines …
Methionine C-11
Investigational
Matched Synonyms: … 2-Amino-4-[11C]methylsulfanyl-butanoic acid, l-[S methyl[11C]methionine …
Matched Iupac: … (2S)-2-amino-4-[(11C)methylsulfanyl]butanoic acid …
Matched Iupac: … (2S)-2-amino-4-[(11C)methylsulfanyl]butanoic acid …
BMS-986251
BMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis).
Investigational
Matched Synonyms: … PERFLUOROPROPAN-2-YL)-2,3,3A,4,5,9B-HEXAHYDRO-1H-BENZO(E)INDOLE-3-CARBONYL)-3-METHYLCYCLOHEXANE-1-CARBOXYLIC ACID …
Matched Description: … NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and …
Matched Description: … NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and …
Sevelamer
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Salts name: … Sevelamer hydrochloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Bile Acid Sequestrants …
Matched Products: … Sevelamer Hydrochloride ... Sevelamer hydrochloride …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Bile Acid Sequestrants …
Matched Products: … Sevelamer Hydrochloride ... Sevelamer hydrochloride …
Displaying drugs 2101 - 2125 of 2754 in total