Displaying drugs 2101 - 2125 of 2795 in total
Cilofexor
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
SPH-3127
SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety of SPH3127 in Patients With Mild-moderate Essential Hypertension).
Investigational
Matched Synonyms: … CARBAMIC ACID, N-(3-(3-((1R)-1-(CYCLOPROPYL((2R)-2-MORPHOLINYLCARBONYL)AMINO)ETHYL)-6-METHYL-1H-PYRAZOLO …
Matched Description: … SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety …
Matched Description: … SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety …
Chloroquine
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched Synonyms: … N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine …
Matched Description: … treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and ... [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... chloroquine and proguanil …
Matched Description: … treat malaria until the development of newer antimalarials such as [pyrimethamine], [artemisinin], and ... [A191787] Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment ... of a number of other conditions including HIV, systemic lupus erythematosus, and rheumatoid arthritis …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... chloroquine and proguanil …
Levomilnacipran
Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Synonyms: … CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)- …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is ... [A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does ... [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for …
Matched Categories: … Milnacipran and enantiomer ... Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is ... [A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does ... [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for …
Matched Categories: … Milnacipran and enantiomer ... Serotonin and Noradrenaline Reuptake Inhibitors …
Efzofitimod
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
Cetyltrimethylammonium naproxenate
Experimental
Matched Categories: … Naphthaleneacetic Acids …
Matched Products: … FLUIMUCIL GOLA …
Matched Products: … FLUIMUCIL GOLA …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … 2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid ... pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Salts name: … Ertapenem sodium …
Matched Products: … Ertapenem Sodium …
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Salts name: … Ertapenem sodium …
Matched Products: … Ertapenem Sodium …
Benzonatate
Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs...
Approved
Matched Synonyms: … p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol ester ... 4-(butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester …
Matched Description: … A5790] Because its chemical structure resembles that of the anesthetic agents in the para-amino-benzoic acid ... Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... [A189519] It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs and …
Matched Categories: … Cough and Cold Preparations …
Matched Description: … A5790] Because its chemical structure resembles that of the anesthetic agents in the para-amino-benzoic acid ... Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... [A189519] It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs and …
Matched Categories: … Cough and Cold Preparations …
Disufenton
Investigational
Matched Synonyms: … 1,3-benzenedisulfonic acid, 4-(((1,1-dimethylethyl)oxidoimino)methyl)- ... 4-(((1,1-dimethylethyl)oxidoimino)methyl)-1,3-benzenedisulfonic acid …
Matched Salts name: … Disufenton sodium …
Matched Categories: … Arylsulfonic Acids ... Sulfur Acids ... Sulfonic Acids …
Matched Salts name: … Disufenton sodium …
Matched Categories: … Arylsulfonic Acids ... Sulfur Acids ... Sulfonic Acids …
ABBV-011
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Matched Synonyms: … an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related …
Matched Description: … ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting …
Matched Description: … ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting …
Quinagolide
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis . Newer dopamine receptor agonists such as quinagolide and DB00248 are...
Approved
Investigational
Matched Synonyms: … (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin …
Matched Description: … Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido ... Newer dopamine receptor agonists such as quinagolide and [DB00248] are shown to effectively inhibit prolactin ... Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Description: … Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido ... Newer dopamine receptor agonists such as quinagolide and [DB00248] are shown to effectively inhibit prolactin ... Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the …
Matched Categories: … Genito Urinary System and Sex Hormones …
2,3-Bis-Benzo[1,3]Dioxol-5-Ylmethyl-Succinic Acid
Experimental
Matched Name: … 2,3-Bis-Benzo[1,3]Dioxol-5-Ylmethyl-Succinic Acid …
Matched Iupac: … (2S,3S)-2,3-bis[(2H-1,3-benzodioxol-5-yl)methyl]butanedioic acid …
Matched Iupac: … (2S,3S)-2,3-bis[(2H-1,3-benzodioxol-5-yl)methyl]butanedioic acid …
8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid
Experimental
Matched Name: … 8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid …
Matched Iupac: … (8S)-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7,8-dihydroquinoline-2-carboxylic acid …
Matched Iupac: … (8S)-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7,8-dihydroquinoline-2-carboxylic acid …
3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
Experimental
Matched Name: … 3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester …
PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE]
Experimental
Matched Name: … PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] …
(3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid
Experimental
Matched Name: … (3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid …
Matched Iupac: … (3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid …
Matched Iupac: … (3S)-1-(2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic acid …
9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid
Experimental
Matched Name: … 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid …
Matched Iupac: … 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid …
Matched Iupac: … 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid …
1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID
Experimental
Matched Name: … 1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID …
Matched Iupac: … 5-{[(4-nitrophenyl)methyl](phosphonomethyl)amino}pentanoic acid …
Matched Iupac: … 5-{[(4-nitrophenyl)methyl](phosphonomethyl)amino}pentanoic acid …
(1R)-2-PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID
Experimental
Matched Name: … (1R)-2-PHENYLACETAMIDO-2-(3-CARBOXYPHENYL)ETHYL BORONIC ACID …
Matched Iupac: … 3-[(2R)-2-(dihydroxyboranyl)-2-(2-phenylacetamido)ethyl]benzoic acid …
Matched Iupac: … 3-[(2R)-2-(dihydroxyboranyl)-2-(2-phenylacetamido)ethyl]benzoic acid …
(2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid
Experimental
Matched Name: … (2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid …
Matched Iupac: … (2R)-2-benzyl-4,4-dihydroxy-5-nitropentanoic acid …
Matched Iupac: … (2R)-2-benzyl-4,4-dihydroxy-5-nitropentanoic acid …
3-(5-methoxy-1H-indol-3-yl)propanoic acid
Experimental
Matched Name: … 3-(5-methoxy-1H-indol-3-yl)propanoic acid …
Matched Iupac: … 3-(5-methoxy-1H-indol-3-yl)propanoic acid …
Matched Iupac: … 3-(5-methoxy-1H-indol-3-yl)propanoic acid …
2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid
Metabolic product of biphenyl; from Pseudomonas putida.
Experimental
Matched Name: … 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid …
Matched Iupac: … (2Z,4E)-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid …
Matched Categories: … Fatty Acids …
Matched Iupac: … (2Z,4E)-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid …
Matched Categories: … Fatty Acids …
3-[(4-Carboxy-2-hydroxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid
Experimental
Matched Name: … 3-[(4-Carboxy-2-hydroxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid …
Matched Iupac: … 3-[(4-carboxy-2-hydroxyphenyl)sulfamoyl]thiophene-2-carboxylic acid …
Matched Iupac: … 3-[(4-carboxy-2-hydroxyphenyl)sulfamoyl]thiophene-2-carboxylic acid …
N-[(6-butoxynaphthalen-2-yl)sulfonyl]-D-glutamic acid
Experimental
Matched Name: … N-[(6-butoxynaphthalen-2-yl)sulfonyl]-D-glutamic acid …
Matched Iupac: … (2R)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
Matched Iupac: … (2R)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
(2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID
Experimental
Matched Name: … (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID …
Matched Iupac: … (2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid …
Matched Iupac: … (2E,4E,7S)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid …
Displaying drugs 2101 - 2125 of 2795 in total