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Displaying drugs 2101 - 2125 of 9627 in total
Benzyl benzoate
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so...
Approved
Matched Description: … Benzyl benzoate is one of the older preparations used to treat scabies. ... It is also used to treat lice infestation of the head and body. ... Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. …
Mepyramine
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication...
Approved
Vet approved
Stannous chloride
Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis...
Approved
Matched Description: … allowing for imaging of areas of altered osteogenesis or necrotic heart tissue [FDA Label]. ... Stannous chloride is used as a source of tin in radiopharmaceutical kits. ... These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) …
Colesevelam
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … the amount of cholesterol and certain fatty substances in the blood. ... Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce …
Secretin human
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Description: … of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification ... of the ampulla of Vater and accessory papilla during endoscopic retrograde cholangiopancreatography ... The main action of secretin is to stimulate the pancreas to secrete pancreatic juice for pH regulation …
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Description: … It is encoded by the most predominant of nine observed haplotypes of this gene. ... of lysosomal glycogen. ... degradation of glygogen to glucose in lysosomes. …
Procyclidine
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Approved
Matched Description: … A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
Flucytosine
A fluorinated cytosine analog that is used as an antifungal agent.
Approved
Investigational
Valrubicin
Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Description: … It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. ... Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder …
Silver
Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity. Silver exists as a pure elemental form, alloy with other metals, and mineral. Having critical roles in various applications inducing chemical and...
Approved
Investigational
Matched Description: … However, some drawbacks of dental use of silver compounds include tooth discolouration and pulp irritation ... Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table ... Silver and its compounds have been used in trials studying the management of dental caries since the …
Influenza B virus B/Austria/1359417/2021 recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Description: … This defense includes the production of humoral immunity through the development of antibodies and of ... A seasonally-specific component of the influenza vaccine. ... cell-mediated immunity through the production of T-lymphocytes. …
Efgartigimod alfa
Myasthenia gravis (MG) is an autoimmune disorder characterized by significant muscle weakness - particularly in the eye, throat, and extremities - caused by autoantibodies attacking the neuromuscular junction. The production of IgG autoantibodies against acetylcholine receptors (AChRs) is one of the more common pathophysiological mechanisms behind MG, and results in...
Approved
Investigational
Matched Description: … [A243759] The production of IgG autoantibodies against acetylcholine receptors (AChRs) is one of the ... (FcRn) used in the treatment of MG. ... IgG, effectively lowering circulating levels of IgG autoantibodies against AChRs. …
Peginterferon alfa-2a
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Description: … Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat ... Use of Peginterferon alfa-2a is associated with a wide range of severe adverse effects including the ... reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma …
Mipomersen
Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. Mipomersen is indicated in...
Approved
Investigational
Matched Description: … Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein ... Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic ... Due to this serious risk of liver toxicity, mipomersen sodium is only available to patients under the …
Lacidipine
Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia . It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce...
Approved
Investigational
Matched Description: … the drug in the membrane and slow rate of membrane washout [A31539]. ... These results may explain the long clinical half-life of lacidipine [A31539]. ... Due to its long duration of action, lacidipine does not lead to reflex tachycardia [A31536]. …
Xylose
Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group. Xylose is a sugar isolated from wood. D-Xylose is a sugar widely used as a diabetic sweetener in food and beverage. Xylose has also been used as a diagnostic agent to observe...
Approved
Matched Description: … Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional ... The dextrorotary form of xylose, D-xylose, refers usually to the endogenously occurring form of the sugar ... Reduction of xylose by catalytic hydrogenation produces the common food additive sweetener substitute …
Tasonermin
Tasonermin is recombinant soluble form tumor necrosis factor α produced via Escherichia coli cell culture. It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery for the subsequent removal of the tumor and in palliative care for irresectable soft...
Approved
Matched Description: … of the limbs as the product Beromun. ... for the subsequent removal of the tumor and in palliative care for irresectable soft tissue sarcoma ... It was approved for use by the European Medicines Agency in April of 1999 for use as an adjunt to surgery …
Tositumomab
Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Approved
Investigational
Matched Description: … chains of 220 residues). ... It is produced in an antibiotic-free culture of mammalian cells. ... It can be covalently linked to Iodine 131 (a radioactive isotope of iodine). …
Peginesatide
Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. Peginesatide...
Approved
Investigational
Matched Description: … not a replica of the structure itself. ... Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. ... Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is …
Magnesium glycinate
Magnesium glycinate is a magnesium salt of glycine that is available as dietary supplements as a source of magnesium. It is used in the treatment of magnesium deficiency.
Approved
Matched Description: … of magnesium. ... It is used in the treatment of magnesium deficiency. ... Magnesium glycinate is a magnesium salt of glycine that is available as dietary supplements as a source …
Butenafine
Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Description: … Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. ... in the formation of sterols necessary for fungal cell membranes. ... In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential …
Margetuximab
The HER2 oncoprotein, the product of the human ERBB2/mouse neu genes, is a member of the HER family of receptor tyrosine kinases that includes the epidermal growth factor receptor (EGFR). Of the various subtypes of breast cancer, HER2-positive breast cancer is characterized by ERBB2 overexpression, a higher grade, a more...
Approved
Investigational
Matched Description: … The HER2 oncoprotein, the product of the human _ERBB2_/mouse _neu_ genes, is a member of the HER family ... Of the various subtypes of breast cancer, HER2-positive breast cancer is characterized by _ERBB2_ overexpression ... of receptor tyrosine kinases that includes the epidermal growth factor receptor (EGFR). …
Streptozocin
An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Approved
Investigational
Anistreplase
Human tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells. Eminase is a lyophilized (freeze-dried) formulation of anistreplase, the p-anisoyl derivative of the primary Lys-plasminogen-streptokinase activator complex (a complex of Lys-plasminogen and streptokinase). A p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human Plasma-derived...
Approved
Matched Description: … Eminase is a lyophilized (freeze-dried) formulation of anistreplase, the p-anisoyl derivative of the ... A p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human ... primary Lys-plasminogen-streptokinase activator complex (a complex of Lys-plasminogen and streptokinase …
Displaying drugs 2101 - 2125 of 9627 in total