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Displaying drugs 2126 - 2150 of 2789 in total
Experimental
Matched Name: … 3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER …
Experimental
Matched Name: … 3-ETHYL-6-{[(4-FLUOROPHENYL)SULFONYL]AMINO}-2-METHYLBENZOIC ACID
Matched Iupac: … 3-ethyl-6-(4-fluorobenzenesulfonamido)-2-methylbenzoic acid
Experimental
Matched Name: … 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid
Matched Iupac: … 5-[(3-carbamoylphenyl)methyl]-5H,6H,7H,8H,9H,10H-cyclohepta[b]indole-4-carboxylic acid
Experimental
Matched Name: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid
Matched Iupac: … 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid
Experimental
Matched Name: … 6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID
Matched Iupac: … 6-{4-[hydroxy(4-nitrophenoxy)phosphoryl]butanamido}hexanoic acid
Experimental
Matched Name: … (2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID
Matched Iupac: … (2E)-3-[2-(oct-1-yn-1-yl)phenyl]prop-2-enoic acid
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Mixtures name: … Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Propranolol hydrochloride
Matched Categories: … Beta Blocking Agents and Thiazides ... propranolol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... propranolol and other combinations ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … Propranolol Hydrochloride ... Propranolol Hydrochloride ER ... Propranolol hydrochloride
Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Description: … As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. ... (Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single …
Matched Salts name: … Diamorphine hydrochloride
Matched Products: … Diacetylmorphine Hydrochloride ... Diamorphine Hydrochloride Inj 30mg/ml BP ... Diamorphine Hydrochloride Inj 100mg/ml BP …
Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Investigational
Matched Synonyms: … MONOCLONAL ALXN1720 SINGLE-DOMAIN VHH FRAGMENT) FUSION PROTEIN WITH PEPTIDE LINKER (SYNTHETIC 15 AMINO-ACID
Matched Description: … Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in …
A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid
Matched Iupac: … 9-ethyl-4,6-dioxo-10-propyl-4H,6H,9H-chromeno[7,6-b]pyridine-2,8-dicarboxylic acid
Matched Description: … are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and
Matched Categories: … Decongestants and Antiallergics …
Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. It is a beta-2-adrenergic receptor agonist. Bitolterol was withdrawn from the market by Elan Pharmaceuticals in 2001.
Withdrawn
Matched Synonyms: … bis(4-methylbenzoic acid) 4-[2-(tert-butylamino)-1-hydroxyethyl]-1,2-phenylene ester …
Matched Description: … Bitolterol mesylate was used to treat bronchospasms in asthma and COPD. …
Experimental
Matched Name: … 3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide
One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … ethyl]-1H-1,2,3,4-tetrazol-5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative …
Matched Salts name: … Cefotiam hydrochloride
Matched Categories: … Thiazines
Experimental
Matched Synonyms: … bromo-N-hydroxyanilino)-hydroxymethyl]sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Matched Iupac: … bromophenyl)(hydroxy)amino](hydroxy)methyl]sulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Nine amino acid polypeptide derived from proteinase 3 …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Synonyms: … [3(S)-endo]-α-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester …
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate...
Approved
Matched Description: … An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment ... It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. ... Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively …
Matched Salts name: … Molindone hydrochloride
Matched Products: … Molindone Hydrochloride
A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Approved
Investigational
Matched Description: … A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain …
Matched Salts name: … Mecamylamine hydrochloride
Matched Categories: … Secondary and Tertiary Amines …
Matched Products: … Mecamylamine Hydrochloride
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Description: … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal ... reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and
Matched Salts name: … Alosetron hydrochloride
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Alosetron Hydrochloride
Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Description: … Butenafine hydrochloride is a synthetic benzylamine antifungal agent. …
Matched Salts name: … Butenafine hydrochloride
Matched Products: … Butenafine Hydrochloride 1% ... Butenafine Hydrochloride ... Butenafine Hydrochloride Jock Itch …
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Description: … H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory ... cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and
Matched Salts name: … Epinastine hydrochloride
Matched Categories: … Decongestants and Antiallergics ... Acid Reducers …
Matched Products: … Epinastine Hydrochloride ... RELESTAT (EPINASTINE HYDROCHLORIDE OPHTHALMIC SOLUTION 0.5 MG/ML) ... RELESTAT (EPINASTINE HYDROCHLORIDE OPTHALMIC SOLUTION) 0.5mg/ml …
An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Approved
Matched Description: … It has been used to treat hypertension and as a peripheral vasodilator. …
Matched Salts name: … Phenoxybenzamine hydrochloride
Matched Products: … Phenoxybenzamine Hydrochloride ... Phenoxybenzamine hydrochloride
Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Synonyms: … 2-(β-methylaminoethyl)pyridine ... 2-[2-(methylamino)ethyl]pyridine
Matched Description: … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... It has a significant impact on both the physical and social functioning of affected individuals. …
Matched Salts name: … Betahistine hydrochloride
Matched Products: … BETAHISTINE HYDROCHLORIDE
Investigational
Matched Synonyms: … insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase (acid
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 2126 - 2150 of 2789 in total