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Displaying drugs 2126 - 2150 of 15256 in total
Approved
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication...
Approved
Vet approved
Matched Description: … However, it rapidly permeates the brain and so often causes drowsiness as a side effect. ... It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered …
Matched Mixtures name: … Acetaminophen,Caffeine and Pyrilamine Maleate ... Pyrilamine Maleate and Phenylephrine Hydrochloride …
Matched Categories: … Hypnotics and Sedatives …
Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010. For further information on the components of this mixture...
Approved
Investigational
Matched Description: … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and ... [L2510] For further information on the components of this mixture please visit [DB11065], [DB11066] and ... [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved …
Matched Mixtures name: … Pancreatin and Enzyme Formula - Tablet …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Iupac: … ,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acid
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched Description: … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. ... Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate....
Approved
Investigational
Matched Description: … Known adverse effects include nausea and headache as well as more serious immunologic and hematological ... kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and ... tofacitinib has also been studied in clinical trials for the prevention of organ transplant rejection, and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Description: … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
Approved
Investigational
Matched Description: … and Vomiting. ... Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. ... Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea …
Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body...
Approved
Matched Description: … Calcium is also needed for the heart, muscles, and nervous system to work properly. …
Matched Categories: … Alimentary Tract and Metabolism …
Lasmiditan is an oral medication used in the termination of migraine headaches that was first approved for use in the United States in October 2019.[L9338,L9356] It was also approved by the European Commission on August 17, 2022. Traditionally, the triptan class of anti-migraine medications (e.g. sumatriptan) have seen preferential use...
Approved
Investigational
Matched Description: … lability and other cardiovascular side effects - for this reason, these medications are less suitable ... seen preferential use in the acute treatment of migraines due to their relatively favourable efficacy and ... Their use is not devoid of concerns, however, and their vasoconstrictive activity can lead to blood pressure …
Saquinavir is an HIV-1 protease inhibitor used in combination with ritonavir and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection. In 1995 it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical use today due to a...
Approved
Investigational
Matched Description: … Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals ... it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and ... the co-administration of ritonavir - a potent enzyme inhibitor - that increases the bioavailability and
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide ... is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA ... Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than …
Matched Categories: … Benzamides and benzamide derivatives …
Chlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. He discovered that this antibiotic was the product of an actinomycete strain he...
Approved
Investigational
Vet approved
Matched Description: … Chlortetracycline is a _tetracycline_ antibiotic, and historically the first member of this class to ... He discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment …
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Approved
Matched Categories: … Nucleic Acid Synthesis Inhibitors …
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Description: … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures ... anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Festuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units....
Approved
Investigational
Vet approved
Matched Description: … The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and ... [A32011] Many bacteria, like _Leuconostoc_, can synthesize dextran from sucrose, and this activity is ... It is produced from certain bacteria that with α-1,6 glycosidic linkages between glucose molecules and
Matched Mixtures name: … Redness reliever and Lubricant ... Meijer Advanced Redness and Irritation Relief …
Matched Categories: … Blood and Related Products ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Description: … [A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the ... [A19739] Approved in the US, Canada, and Europe, stiripentol is used to treat seizures associated …
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Approved
Bordetella pertussis pertactin antigen is a vaccine for the prophylaxis of whooping cough that contains pertactin, a membrane-associated antigen of Bordetella pertussis .
Approved
Investigational
Matched Mixtures name: … FILAMENTOUS HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Description: … Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and ... [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission ... currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations...
Approved
Matched Categories: … Antineoplastic and Immunomodulating Agents …
A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Description: … A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining …
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Matched Description: … other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and
Matched Categories: … Genito Urinary System and Sex Hormones …
Displaying drugs 2126 - 2150 of 15256 in total