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Displaying drugs 2176 - 2200 of 15759 in total

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... by inhibiting glucose reabsorption in the proximal tubule of the nephron and causing glycosuria. ... [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control …
Matched Mixtures name: … Dapagliflozin and Metformin Hydrochloride ... Dapagliflozin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and dapagliflozin ... saxagliptin and dapagliflozin ... sitagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …

Teduglutide

Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Description: … Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). ... It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Various Alimentary Tract and Metabolism Products ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Kinetin

Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. It was shown to naturally exist in DNA of organisms including humans and various plants. While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging...
Approved
Matched Iupac: … N-[(furan-2-yl)methyl]-7H-purin-6-amine …
Matched Description: … Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. ... It was shown to naturally exist in DNA of organisms including humans and various plants. …

Elymus repens pollen

Elymus repens pollen is the pollen of the Elymus repens plant. Elymus repens pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Categories: … Cell-mediated Immunity …

Urochloa mutica pollen

Urochloa mutica pollen is the pollen of the Urochloa mutica plant. Urochloa mutica pollen is mainly used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …

Lolium perenne subsp. multiflorum pollen

Lolium perenne subsp. multiflorum pollen is the pollen of the Lolium perenne subsp. multiflorum plant. Lolium perenne subsp. multiflorum pollen is mainly used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …

Lenalidomide

Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Description: … Lenalidomide works through various mechanisms of actions that promote malignant cell death and enhance ... multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal ... and toxicities. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Hyaluronidase (human recombinant)

A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Description: … fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. ... [A4033] Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Hyaluronidase

Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … fluids, drugs, and contrast agents. ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. ... Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs …

Saccharomyces cerevisiae

Saccharomyces cerevisiae is a fungus which can provoke allergic reactions. Saccharomyces cerevisiae is used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …

Mustard seed

Mustard seed allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …

Flax seed

Flax seed allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …

Festuca pratensis pollen

Festuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Categories: … Cell-mediated Immunity …

Choline C 11

Choline C 11 is a marker for cellular proliferation as its main molecule is a precursor for the biosynthesis of phospholipids which are essential components of all cell membranes. It was developed by MCPRF and FDA first approved in September 2012.
Approved
Investigational
Matched Iupac: … (2-hydroxyethyl)((¹¹C)methyl)dimethylazanium chloride …
Matched Description: … [A32041] It was developed by MCPRF and FDA first approved in September 2012. ... molecule is a precursor for the biosynthesis of phospholipids which are essential components of all cell …

Iobenguane sulfate I-123

Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].
Approved
Investigational
Matched Iupac: … bis(N-{[3-(¹²³I)iodophenyl]methyl}guanidine); sulfuric acid …

Cholecystokinin

Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Description: … cell growth, energy production, gene expression and protein synthesis, processes that have profound ... In addition to its roles in promoting smooth muscle cell contraction/exocrine cell secretion, CCK promotes ... in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive …
Matched Categories: … Cholagogues and Choleretics ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Rhizopus arrhizus var. arrhizus

Rhizopus arrhizus var. arrhizus is a fungus which can provoke allergic reactions. Rhizopus arrhizus var. arrhizus extract is used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …

Ustilago nuda hordei

Ustilago nuda hordei is a fungus which can provoke allergic reactions. Ustilago nuda hordei extract is used in allergenic testing.
Approved
Matched Categories: … Cell-mediated Immunity …

Penciclovir

Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Description: … Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …

Lisdexamfetamine

Lisdexamfetamine is a prodrug of dextroamphetamine, a central nervous system stimulant known as d-amphetamine, covalently attached to the naturally occurring amino acid L-lysine. Lisdexamfetamine is the first chemically formulated prodrug stimulant and was first approved by the FDA in April 2008. It was also approved by Health Canada in February...
Approved
Investigational
Matched Description: … system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid ... [A2230] by blocking dopamine and norepinephrine reuptake and increasing their levels in the extraneuronal ... [A2230] Lisdexamfetamine is the first chemically formulated prodrug stimulant [A40246] and was first …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Bacampicillin

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … of the biosynthesis of cell wall mucopeptides. ... It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract ... and acute uncomplicated gonococcal urethritis etc. …

Quaternium-15

Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. In 2005,...
Approved
Experimental
Matched Description: … Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including …
Matched Categories: … Cell-mediated Immunity …

Tetraferric tricitrate decahydrate

Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.
Approved
Matched Description: … Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and …
Matched Mixtures name: … Maxine Vitamin and Mineral Supplement …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Fomepizole

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Iupac: … 4-methyl-1H-pyrazole …
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …

Luliconazole

Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan.
Approved
Matched Description: … It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. ... agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell …
Matched Categories: … Imidazole and Triazole Derivatives …
Displaying drugs 2176 - 2200 of 15759 in total