Displaying drugs 2201 - 2225 of 2852 in total
N-methylnicotinamide
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … Nicotinic acid methylamide …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Acids, Heterocyclic ... Nicotinic Acids …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester …
Matched Description: … [L43402] The pharmacological profile of chloroprocaine is characterized by a short latency and duration ... [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Description: … [L43402] The pharmacological profile of chloroprocaine is characterized by a short latency and duration ... [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid …
RU85053
Experimental
Matched Synonyms: … Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]propyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Matched Iupac: … [1,1'-biphenyl]-4-yl}methyl)-2-oxoazepan-3-yl]carbamoyl}-2-acetamidoethyl]-2-(carboxymethyl)benzoic acid …
Acrivastine
Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension, edema, bronchoconstriction, and tachycardia.
Acrivastine is...
Approved
Matched Synonyms: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}acrylic acid …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... , edema, bronchoconstriction, and tachycardia. ... As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby …
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H1 Antagonists, Non-Sedating …
Matched Iupac: … (2E)-3-{6-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridin-2-yl}prop-2-enoic acid …
Matched Description: … Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever ... , edema, bronchoconstriction, and tachycardia. ... As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby …
Matched Categories: … Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H1 Antagonists, Non-Sedating …
Cianidanol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Synonyms: … Catechuic acid …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
NP-51
Investigational
Matched Synonyms: … (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime …
Vipoglanstat
Investigational
Matched Synonyms: … dimethyl-propionylamino)-methyl]-phenylamino}-6-(2,2-difluoroethoxy)-1-methyl-1H-benzoimidazole-5-carboxylic acid …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid ... 5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Levofloxacin
Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Synonyms: … methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid ... methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid ... dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Matched Iupac: … methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic acid …
Matched Description: … Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... [A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive …
Matched Categories: … Alimentary Tract and Metabolism ... levofloxacin and ornidazole ... Metabolic Side Effects of Drugs and Substances ... lansoprazole, amoxicillin and levofloxacin …
Propantheline
A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Approved
Matched International brands: … Prokind …
Matched Description: … A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment …
Matched Categories: … Alimentary Tract and Metabolism ... propantheline and psycholeptics …
Matched Description: … A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment …
Matched Categories: … Alimentary Tract and Metabolism ... propantheline and psycholeptics …
Pixofisiran
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Stp-705 component tgf-.beta.1 si-rna free acid ... Tgf-.beta.1 si-rna free acid component of cotsiranib …
Gentian violet cation
A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Description: … A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … El Valle Gentian Violet …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … El Valle Gentian Violet …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE …
Matched Iupac: … (2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]-3-methylpentanoic acid …
Matched Iupac: … (2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanamido]-3-methylpentanoic acid …
Fibroblast growth factor-1
Investigational
Matched Synonyms: … Acidic fibroblast growth factor ... Fibroblast growth factor, acidic ... Acidic fibroblast growth factor (aFGF) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Fotemustine
Investigational
Matched Synonyms: … PHOSPHONIC ACID, (1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER ... PHOSPHONIC ACID, P-(1-((((2-CHLOROETHYL)NITROSOAMINO)CARBONYL)AMINO)ETHYL)-, DIETHYL ESTER …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Methyldopa
Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Synonyms: … 3-Hydroxy-alpha-methyl-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug ... alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition of adrenergic neuronal outflow and …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Aromatic L-amino Acid Decarboxylase Inhibitors …
Matched Iupac: … (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid …
Matched Description: … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug ... alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition of adrenergic neuronal outflow and …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Aromatic L-amino Acid Decarboxylase Inhibitors …
1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE
Experimental
Matched Name: … 1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE …
Trioxsalen
Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of...
Approved
Matched Synonyms: … 6-hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid, δ-lactone …
Matched Description: … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative ... conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage …
Matched Description: … Trioxsalen (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative ... conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and ... In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage …
Gavorestat
Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
Investigational
Matched Synonyms: … Oxo-3-((5-(Trifluoromethyl)Benzo[D]Thiazol-2-Yl)Methyl)-3,4-Dihydrothieno[3,4-D]Pyridazin-1-Yl)Acetic Acid …
Matched Iupac: … -oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3H,4H-thieno[3,4-d]pyridazin-1-yl)acetic acid …
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD …
Matched Iupac: … -oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3H,4H-thieno[3,4-d]pyridazin-1-yl)acetic acid …
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD …
1,3-Propanediol
Experimental
Matched Synonyms: … Propane-1,3-diol …
Matched Iupac: … propane-1,3-diol …
Matched Iupac: … propane-1,3-diol …
3'-Fluoro-3'-deoxythymidine 5'-monophosphate
Experimental
Matched Synonyms: … 5'-Thymidylic acid, 3'-deoxy-3'-fluoro- …
Matched Iupac: … ,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … ,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
S-(N-hydroxy-N-iodophenylcarbamoyl)glutathione
Experimental
Matched Synonyms: … carboxymethylamino)-3-[(R)-hydroxy-(N-hydroxy-4-iodoanilino)methyl]sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid …
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(R)-hydroxy[hydroxy(4-iodophenyl)amino]methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
Matched Iupac: … carboxymethyl)carbamoyl]-2-{[(R)-hydroxy[hydroxy(4-iodophenyl)amino]methyl]sulfanyl}ethyl]carbamoyl}butanoic acid …
Carindacillin
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Synonyms: … 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acid …
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
NNC-55-0396 free base
NNC-55-0396 is a T-type Ca(2+) channel inhibitor.
Investigational
Matched Synonyms: … Cyclopropanecarboxylic acid, (1s,2s)-2-(2-((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-6-fluoro …
Displaying drugs 2201 - 2225 of 2852 in total