Displaying drugs 201 - 225 of 332 in total
Chloric acid
Approved
Experimental
Matched Name: … Chloric acid …
Matched Iupac: … chloric acid …
Matched Salts name: … Potassium chlorate …
Matched Products: … Hemodialysis Acid Concentrate …
Matched Iupac: … chloric acid …
Matched Salts name: … Potassium chlorate …
Matched Products: … Hemodialysis Acid Concentrate …
Chlorthalidone
Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys through inhibition of the Na+/Cl− symporter in the distal convoluted tubule...
Approved
Matched Synonyms: … 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide ... 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide ... 1-oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... chlortalidone and potassium ... Non Potassium Sparing Diuretics ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Iupac: … 2-chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... chlortalidone and potassium ... Non Potassium Sparing Diuretics ... chlortalidone and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Ticagrelor
Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, .
Ticagrelor was...
Approved
Matched Synonyms: … (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo ... (4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol …
Matched Iupac: … (1S,2S,3R,5S)-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo ... [4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol …
Matched Description: … Ticagrelor was granted EMA approval on 3 December 2010. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 Substrates …
Matched Iupac: … (1S,2S,3R,5S)-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo ... [4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol …
Matched Description: … Ticagrelor was granted EMA approval on 3 December 2010. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 Substrates …
Metronidazole
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Synonyms: … 2-methyl-3-(2-hydroxyethyl)-4-nitroimidazole ... 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrrole ... 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol …
Matched Salts cas: … 69198-10-3 …
Matched Mixtures name: … Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... Metronidazole 1% / Niacinamide 4% ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Drugs for Acid Related Disorders ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Substrates …
Matched Products: … Metrogel 1% ... AMEFAR(R) TABLETA VAGINAL500 MG ... Braun 5 mg/ml Infusionslösung …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol …
Matched Salts cas: … 69198-10-3 …
Matched Mixtures name: … Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... Metronidazole 1% / Niacinamide 4% ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Drugs for Acid Related Disorders ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Substrates …
Matched Products: … Metrogel 1% ... AMEFAR(R) TABLETA VAGINAL500 MG ... Braun 5 mg/ml Infusionslösung …
Sufentanil
Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. It is administered by the intravenous, epidural and sublingual routes.
Also known as Dsuvia, the sublingual form is used for the management of acute pain in adults that...
Approved
Investigational
Matched Synonyms: … N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide ... N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … (AcelRx), was approved on November 2, 2018 [L4717]. …
Matched Salts cas: … 60561-17-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Products: … Sufentanil Panpharma 5 Mikrogramm/ml Injektionslösung ... Sufentanil-hameln 5 Mikrogramm/ml Injektions-/Infusionslösung ... Sufentanil Kalceks 5 Mikrogramm/ml Injektions-/Infusionslösung …
Matched Iupac: … N-[4-(methoxymethyl)-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl]-N-phenylpropanamide …
Matched Description: … (AcelRx), was approved on November 2, 2018 [L4717]. …
Matched Salts cas: … 60561-17-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Products: … Sufentanil Panpharma 5 Mikrogramm/ml Injektionslösung ... Sufentanil-hameln 5 Mikrogramm/ml Injektions-/Infusionslösung ... Sufentanil Kalceks 5 Mikrogramm/ml Injektions-/Infusionslösung …
Acetazolamide
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Synonyms: … 5-acetamido-1,3,4-thiadiazole-2-sulfonamide ... 2-acetylamino-1,3,4-thiadiazole-5-sulfonamide ... 5-acetylamino-1,3,4-thiadiazole-2-sulfonamide …
Matched Iupac: … N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide …
Matched Salts cas: … 1424-27-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Matched Products: … VICLEAR(R) …
Matched Iupac: … N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide …
Matched Salts cas: … 1424-27-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Matched Products: … VICLEAR(R) …
Warfarin
Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally,...
Approved
Matched Synonyms: … 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin …
Matched Iupac: … 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one …
Matched Salts cas: … 129-06-6 …
Matched Salts name: … Warfarin potassium …
Matched Categories: … 4-Hydroxycoumarins ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP2C9 Inducers …
Matched Products: … Coumadin Tab 6 mg ... เบฟาริน 4 ... มาฟอแรน 1 มก. …
Matched Iupac: … 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one …
Matched Salts cas: … 129-06-6 …
Matched Salts name: … Warfarin potassium …
Matched Categories: … 4-Hydroxycoumarins ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP2C9 Inducers …
Matched Products: … Coumadin Tab 6 mg ... เบฟาริน 4 ... มาฟอแรน 1 มก. …
Glucosamine
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Synonyms: … 2-amino-2-deoxy-D-glucose …
Matched Iupac: … (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol …
Matched Salts cas: … 66-84-2 ... 14999-43-0 ... 1296149-08-0 …
Matched Mixtures name: … flexijoint 3-in-1 Joint Care Powder ... OSTEOACTIV 3-in-1 Joint Formula Powder ... ARTROFORT(R) COMPLEX …
Matched Salts name: … Glucosamine sulfate potassium chloride …
Matched Categories: … Amino Sugars …
Matched Products: … GLUCONITRIN(R) - S 1500 MG ... DONA 400 MG 6 AMPUL + 6 COZUCU AMPUL ... VIARTRIL-S …
Matched Iupac: … (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol …
Matched Salts cas: … 66-84-2 ... 14999-43-0 ... 1296149-08-0 …
Matched Mixtures name: … flexijoint 3-in-1 Joint Care Powder ... OSTEOACTIV 3-in-1 Joint Formula Powder ... ARTROFORT(R) COMPLEX …
Matched Salts name: … Glucosamine sulfate potassium chloride …
Matched Categories: … Amino Sugars …
Matched Products: … GLUCONITRIN(R) - S 1500 MG ... DONA 400 MG 6 AMPUL + 6 COZUCU AMPUL ... VIARTRIL-S …
Clotrimazole
This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Synonyms: … 1-(α-(2-Chlorophenyl)benzhydryl)imidazole ... 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole ... 1-(o-Chlorotrityl)imidazole …
Matched Iupac: … 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole …
Matched Mixtures name: … CLONODEX (R) ... LINDAZOL-2 ® ... LINDAZOL-2 ® …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … CLOMACIN-P ... คาจินอล - 5 ... Gyne-Lotrimin 7 …
Matched Iupac: … 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole …
Matched Mixtures name: … CLONODEX (R) ... LINDAZOL-2 ® ... LINDAZOL-2 ® …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … CLOMACIN-P ... คาจินอล - 5 ... Gyne-Lotrimin 7 …
Amiodarone
Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Synonyms: … 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran ... 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran ... 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone …
Matched Iupac: … {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine …
Matched Salts cas: … 19774-82-4 …
Matched Categories: … Potassium Channel Blockers ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein inducers ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates …
Matched Products: … AMIDOVIN 150 MG/3 ML IV ENJEKSİYONLUK ÇÖZELTİ, 6 ADET ... AMIODARONE FARMA 1 ... CORDARONE 150 MG/3 ML IV ENJAKTABL ÇÖZELTİ İÇEREN AMPUL, 6 ADET …
Matched Iupac: … {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine …
Matched Salts cas: … 19774-82-4 …
Matched Categories: … Potassium Channel Blockers ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein inducers ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates …
Matched Products: … AMIDOVIN 150 MG/3 ML IV ENJEKSİYONLUK ÇÖZELTİ, 6 ADET ... AMIODARONE FARMA 1 ... CORDARONE 150 MG/3 ML IV ENJAKTABL ÇÖZELTİ İÇEREN AMPUL, 6 ADET …
Amiloride
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Synonyms: … 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide ... N-amidino-3,5-diamino-6-chloropyrazinecarboxamide …
Matched Iupac: … 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide …
Matched Description: … Negative potential reduces secretion of potassium and hydrogen ions. ... Amiloride is used in conjunction with diuretics to spare potassium loss. …
Matched Salts cas: … 17440-83-4 …
Matched Mixtures name: … Riva-amilzide 5/50 mg ... Nu-amilzide 5/50 Mg Tab …
Matched Categories: … Acid Sensing Ion Channel Blockers ... Potassium-Sparing Diuretics ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide …
Matched Description: … Negative potential reduces secretion of potassium and hydrogen ions. ... Amiloride is used in conjunction with diuretics to spare potassium loss. …
Matched Salts cas: … 17440-83-4 …
Matched Mixtures name: … Riva-amilzide 5/50 mg ... Nu-amilzide 5/50 Mg Tab …
Matched Categories: … Acid Sensing Ion Channel Blockers ... Potassium-Sparing Diuretics ... Heterocyclic Compounds, 1-Ring …
Glycol salicylate
Glycol salicylate, also known as 2-hydroxyethyl salicylate, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid with one of the hydroxy groups of ethylene glycol. It is found as an active ingredient and topical analgesic in patches used to provide relief for mild to...
Approved
Matched Synonyms: … 2-hydroxybenzoic acid 2-hydroxyethyl ester ... 2-hydroxyethyl 2-oxidanylbenzoate ... 2-hydroxyethyl salicylate …
Matched Iupac: … 2-hydroxyethyl 2-hydroxybenzoate …
Matched Description: … hydroxyethyl salicylate_, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid ... Glycol salicylate (GS), composed of salicylic acid (SA) and ethylene glycol, is a non-steroidal anti-inflammatory …
Matched Categories: … Carboxylic Acids …
Matched Iupac: … 2-hydroxyethyl 2-hydroxybenzoate …
Matched Description: … hydroxyethyl salicylate_, is a benzoate ester formed from the condensation of the carboxy group of salicylic acid ... Glycol salicylate (GS), composed of salicylic acid (SA) and ethylene glycol, is a non-steroidal anti-inflammatory …
Matched Categories: … Carboxylic Acids …
Nicotine
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Synonyms: … (S)-3-(1-methylpyrrolidin-2-yl)pyridine ... (S)-3-(N-methylpyrrolidin-2-yl)pyridine ... 3-(2-(N-methylpyrrolidinyl))pyridine …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Salts cas: … 65-31-6 ... 6019-06-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Inducers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2A6 Inhibitors …
Matched Products: … NIQUITIN PARCHE TRANSDERMICO 7 MG. ETAPA 3 ... NICORETTE TRANSDERMAL PATCH 5 mg/16 hr ... Habitrol Step 3 …
Matched Iupac: … 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine …
Matched Salts cas: … 65-31-6 ... 6019-06-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Inducers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2A6 Inhibitors …
Matched Products: … NIQUITIN PARCHE TRANSDERMICO 7 MG. ETAPA 3 ... NICORETTE TRANSDERMAL PATCH 5 mg/16 hr ... Habitrol Step 3 …
Nicorandil
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched Synonyms: … 2-Nicotinamidoethyl nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate ... N-(2-Hydroxyethyl)nicotinamide nitrate (ester) …
Matched Iupac: … 2-[(pyridin-3-yl)formamido]ethyl nitrate …
Matched Description: … Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane ... niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium ... hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration …
Matched Categories: … Potassium Channel Opener ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-[(pyridin-3-yl)formamido]ethyl nitrate …
Matched Description: … Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane ... niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium ... hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration …
Matched Categories: … Potassium Channel Opener ... Heterocyclic Compounds, 1-Ring …
Benzthiazide
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … Thiazides also cause loss of potassium and an increase in serum uric acid. ... Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vonoprazan
Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+-ATPase-mediated gastric acid secretion. PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations. Furthermore, vonoprazan is 350-times more potent...
Approved
Investigational
Matched Synonyms: … 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine …
Matched Iupac: … {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine …
Matched Description: … Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+- ... ATPase-mediated gastric acid secretion. ... PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. …
Matched Categories: … Potassium-competitive Acid Blockers ... Heterocyclic Compounds, 1-Ring ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... P-glycoprotein inhibitors …
Matched Iupac: … {[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrol-3-yl]methyl}(methyl)amine …
Matched Description: … Vonoprazan is a potassium-competitive acid blocker (PCAB) that inhibits H+, K+- ... ATPase-mediated gastric acid secretion. ... PCABs represent an alternative to proton-pump inhibitors for the treatment of acid-related disorders. …
Matched Categories: … Potassium-competitive Acid Blockers ... Heterocyclic Compounds, 1-Ring ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... P-glycoprotein inhibitors …
Valsartan
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine ... N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine ... N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine …
Matched Iupac: … (2S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid …
Matched Description: … ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding ... Valsartan is commonly used for the management of hypertension, heart failure, and Type 2 Diabetes-associated ... statistically significant decreases in urinary albumin and protein excretion in patients diagnosed with type 2 …
Matched Mixtures name: … CARDIK ® 3 160/5/12.5 ... CARDIK ® 3 160/5/12.5 ... AMVAL(R) 10/80 MG TABLETAS …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... Angiotensin 2 Receptor Blocker ... Angiotensin II Type 2 Receptor Blockers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inhibitors …
Matched Products: … Diovan 3 mg/ml Lösung zum Einnehmen …
Matched Iupac: … (2S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid …
Matched Description: … ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding ... Valsartan is commonly used for the management of hypertension, heart failure, and Type 2 Diabetes-associated ... statistically significant decreases in urinary albumin and protein excretion in patients diagnosed with type 2 …
Matched Mixtures name: … CARDIK ® 3 160/5/12.5 ... CARDIK ® 3 160/5/12.5 ... AMVAL(R) 10/80 MG TABLETAS …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... Angiotensin 2 Receptor Blocker ... Angiotensin II Type 2 Receptor Blockers ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inhibitors …
Matched Products: … Diovan 3 mg/ml Lösung zum Einnehmen …
Ibutilide
Ibutilide is a Class III antiarrhythmic agent available in intravenous formulations. It is indicated for the conversion of acute atrial flutter and recent onset atrial fibrillation to normal sinus rhythm (NSR).
Approved
Matched Synonyms: … N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide …
Matched Iupac: … N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide …
Matched Iupac: … N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide …
Bendroflumethiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Mixtures name: … CORGARETIC (NADOLOL/ BENDROFLUMETIAZIDA) 80/5 MG …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... bendroflumethiazide and potassium ... bendroflumethiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Iupac: … 3-benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Mixtures name: … CORGARETIC (NADOLOL/ BENDROFLUMETIAZIDA) 80/5 MG …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... bendroflumethiazide and potassium ... bendroflumethiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Riboflavin
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol ... 6,7-Dimethyl-9-D-ribitylisoalloxazine ... 7,8-Dimethyl-10-ribitylisoalloxazine …
Matched Iupac: … 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione …
Matched Salts cas: … 7681-29-0 …
Matched Mixtures name: … P-NATAL® ... B 6 Plus ... Irospan 24/6 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Products: … Riboflavin-S Tab 25mg ... Riboflavin 5 Phosphate Cap 50mg ... บี 2 - 10 …
Matched Iupac: … 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione …
Matched Salts cas: … 7681-29-0 …
Matched Mixtures name: … P-NATAL® ... B 6 Plus ... Irospan 24/6 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Products: … Riboflavin-S Tab 25mg ... Riboflavin 5 Phosphate Cap 50mg ... บี 2 - 10 …
Duloxetine
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Synonyms: … (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine ... (S)-duloxetine …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 CYP1A2 Substrates …
Matched Products: … DUAX-R ... DULOXETIN 1 A PHA 30MG HKP ... DULOXETIN 1 A PHA 60MG HKP …
Matched Iupac: … methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 CYP1A2 Substrates …
Matched Products: … DUAX-R ... DULOXETIN 1 A PHA 30MG HKP ... DULOXETIN 1 A PHA 60MG HKP …
Manganese cation
Manganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake primarily occurs through the diet, as it is found at low levels in...
Approved
Nutraceutical
Matched Synonyms: … MANGANESE(2+) ... MANGANESE ION(2+) ... MANGANESE CATION (2+) …
Matched Iupac: … manganese(2+) ion …
Matched Salts cas: … 7773-01-5 ... 10034-96-5 …
Matched Mixtures name: … BION 3 FILM COATED TABLET ... Calcium and Magnesium 1:1 Plus Tablets ... For-2 …
Matched Iupac: … manganese(2+) ion …
Matched Salts cas: … 7773-01-5 ... 10034-96-5 …
Matched Mixtures name: … BION 3 FILM COATED TABLET ... Calcium and Magnesium 1:1 Plus Tablets ... For-2 …
Stiripentol
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Synonyms: … 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol ... 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Inducers ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP1A2 Inducers ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Triamterene
Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension. It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side. Since it acts on...
Approved
Matched Synonyms: … 6-phenylpteridine-2,4,7-triamine …
Matched Iupac: … 6-phenylpteridine-2,4,7-triamine …
Matched Description: … Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management ... Triamterene is a weak antagonist of folic acid, and a photosensitizing drug. ... It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion …
Matched Categories: … Potassium-Sparing Diuretics ... Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Matched Iupac: … 6-phenylpteridine-2,4,7-triamine …
Matched Description: … Triamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management ... Triamterene is a weak antagonist of folic acid, and a photosensitizing drug. ... It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion …
Matched Categories: … Potassium-Sparing Diuretics ... Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Dexamethasone
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Synonyms: … 16α-Methyl-9α-fluoro-1-dehydrocortisol ... 1-Dehydro-16α-methyl-9α-fluorohydrocortisone ... 16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol …
Matched Iupac: … (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H ... ,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Salts cas: … 312-93-6 ... 2392-39-4 …
Matched Mixtures name: … NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... R-DIM® ... OFTAMYCIN-DX %0.3 + %0.1 STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML 1 ADET …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Inducers …
Matched Products: … LoCort 7-Day ... HiDex 6-day ... ZonaCort 7-Day …
Matched Iupac: … (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H ... ,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Salts cas: … 312-93-6 ... 2392-39-4 …
Matched Mixtures name: … NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... R-DIM® ... OFTAMYCIN-DX %0.3 + %0.1 STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML 1 ADET …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Inducers …
Matched Products: … LoCort 7-Day ... HiDex 6-day ... ZonaCort 7-Day …
Displaying drugs 201 - 225 of 332 in total