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Displaying drugs 2301 - 2325 of 9591 in total
Tesamorelin
Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.
Approved
Investigational
Matched Description: … Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing ... Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy …
Lanolin alcohols
Lanolin alcohols are a complex combination of organic alcohols obtained by the hydrolysis of lanolin. It is administered as an ointment base with topical insulin and has shown to be antagonistic to wound healing. It is commonly used in allergenic testing.
Approved
Experimental
Matched Description: … Lanolin alcohols are a complex combination of organic alcohols obtained by the hydrolysis of lanolin. …
Diphenidol
Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.
Approved
Investigational
Withdrawn
Matched Description: … Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. …
Temoporfin
Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan.
Approved
Investigational
Matched Description: … Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and …
Brilliant blue G
Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Description: … Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of ... thin and translucent, making it difficult to identify during eye surgeries that require high levels of ... Brilliant blue G, like its name, imparts a vibrant blue color, facilitating identification of the ILM …
Elivaldogene autotemcel
Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy, an X-linked genetic disorder characterized by missing or non-functional ABCD1 gene that codes for ALDP. ALDP is a key protein that normally...
Approved
Matched Description: … destruction of myelin, which is an insulating layer and essential component of nerves. ... Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. ... It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with …
Methoxamine
An alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
Approved
Investigational
Phenylbutazone
A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this...
Approved
Vet approved
Matched Description: … It is especially effective in the treatment of ankylosing spondylitis. …
Practolol
A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Approved
Matched Description: … A beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias. …
Amrinone
Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Approved
Matched Description: … It is used in the treatment of congestive heart failure. …
Spectinomycin
An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Lumateperone
Schizophrenia is a complex mental illness and impacts approximately 1% of the population. Although there are several antipsychotics including aripiprazole, paliperidone and clozapine available for clinical use, they are generally accompanied by significant metabolic and/or neurological adverse effects. Lumateperone is a newly approved 2nd generation antipsychotic currently indicated for the...
Approved
Investigational
Matched Description: … Schizophrenia is a complex mental illness and impacts approximately 1% of the population. ... Lumateperone is a newly approved 2nd generation antipsychotic currently indicated for the treatment of ... glutamate, serotonin and dopamine, which are all neurotransmitters that contribute to the pathophysiology of …
Thiohexam
Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer.
Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Foreskin keratinocyte (neonatal)
Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes. The keratinocytes form a...
Approved
Matched Description: … rates of wound healing and decreasing the time required for closure of wounds [L2452]. ... The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes ... It is composed of epidermal, dermal and hypodermal layers. …
Adenine
A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Description: … A purine base and a fundamental unit of adenine nucleotides. …
Stanozolol
Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes.
Approved
Vet approved
Gallium citrate Ga-67
Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy...
Approved
Matched Description: … Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. ... to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of …
Isoxsuprine
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … It is used in the treatment of peripheral vascular disease and in premature labor. ... A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. …
Dinoprost tromethamine
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Description: … The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine …
Tetrachlorodecaoxide
WF10 is a chlorite-based, immunomodulating drug is developed by Nuvo Research Inc. Certain preclinical evidence and clinical pilot data suggest that WF10 may be effective in treating certain cancers. The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white blood cell) by modulating the...
Approved
Investigational
Matched Description: … in combination with Xeloda (capecitabine) in the treatment of pancreatic cancer. ... The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white ... The Corporation has commenced a Phase II clinical trial in an effort to demonstrate the efficacy of WF10 …
Selenomethionine
Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can be produced from post-structural modifications. In vivo, selenomethionine plays an essential role in acting as an antioxidant, where it depletes...
Approved
Investigational
Matched Description: … In comparison to selenite, which is the inorganic form of selenium, the organic form of selenomethionine ... antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of ... laboratories where its incorporation into proteins that need to be visualized enhances the performance of …
Light green SF yellowish
Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Description: … the dye and increased tendency of the dye to fade. ... The maximum absorption of light green SF yellowish is at 630 (422) nm. ... Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining …
Pegulicianine
Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. It is used following surgical resection of the primary tumor to detect areas of remaining cancer. Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the...
Approved
Matched Description: … It is used following surgical resection of the primary tumor to detect areas of remaining cancer. ... Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence ... [L50537] The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments …
Lebrikizumab
Lebrikizumab is a monoclonal antibody against IL-13 that binds to a different epitope compared tralokinumab.[A262874,A262879]
On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a body weight...
Approved
Investigational
Matched Description: … November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYSS for the treatment of ... the positive results obtained from the Phase 3 studies ADvocate 1 and ADvocate 2, where nearly 80% of ... moderate-to-severe atopic dermatitis in adult and adolescent patients 12 years and older with a body weight of …
Quaternium-15
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. In 2005,...
Approved
Experimental
Matched Description: … contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. ... It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause …
Displaying drugs 2301 - 2325 of 9591 in total