Displaying drugs 2351 - 2375 of 2957 in total
Olokizumab
Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system. IL-6 pathway dysregulation is associated with chronic inflammation and lymphoproliferation, including in autoimmune conditions such as rheumatoid arthritis, Castleman disease, and cytokine release syndrome....
Investigational
Curcuma xanthorrhiza oil
Curcuma xanthorrhiza oil is extracted from Curcuma xanthorrhiza Roxb., a member of the ginger family (Zingiberaceae) that is widely distributed in the region of Southeastern Asia . Curcuma xanthorrhiza is also known as Javanese Turmeric or Temoe Lawak . For centuries, Curcuma xanthorrhiza oil has been used as a traditional...
Nutraceutical
Axatilimab
Axatilimab is under investigation in clinical trial NCT04301778 (Durvalumab in Combination With a CSF-1R Inhibitor (SNDX-6532) Following Chemo or Radio-embolization for Patients With Intrahepatic Cholangiocarcinoma).
Investigational
LY2181308
LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. LY2181308 is known to target baculoviral IAP repeat-containing protein 5. LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung,...
Investigational
Matched Description: … LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer …
Abivertinib
Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies. In binding to and inhibiting EGFR and BTK receptors,...
Investigational
Matched Description: … factor receptor (EGFR) and Bruton's tyrosine kinase (BTK). ... Abivertinib is a tyrosine kinase inhibitor targeted against mutant forms of both human epidermal growth …
Ferrimannitol ovalbumin
Ferrimannitol-ovalbumin (FMOA) is an adduct between ovalbumin and the complex Fe(III)-mannitol.
Experimental
Matched Description: … Ferrimannitol-ovalbumin (FMOA) is an adduct between ovalbumin and the complex Fe(III)-mannitol. …
RAF-265
Investigational
Oregovomab
Oregovomab is a murine monoclonal antibody that attaches to the tumor-associated antigen CA125.
Investigational
ASP-2138
ASP-2138 is a bispecific antibody directed against CLDN18.2 and T cell receptor complex CD3
Investigational
Matched Description: … ASP-2138 is a bispecific antibody directed against CLDN18.2 and T cell receptor complex CD3 …
CP1-1189
CPI-1189 has been used in trials studying the treatment of HIV Infections and AIDS Dementia Complex.
Investigational
Matched Description: … CPI-1189 has been used in trials studying the treatment of HIV Infections and AIDS Dementia Complex. …
MDX-018
MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system. Other possible indications include chronic obstructive pulmonary disease (COPD)...
Investigational
Matched Description: … MDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin- ... pre-clinical studies, HuMax-Inflam has been shown to inhibit tumor growth in tumor models using primary human …
CX-717
CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.
Illicit
Investigational
Mersalyl
Mersalyl is the sodium salt form of mersalyl acid, a mercurial diuretic. It is an outdated drug, and its approval has been discontinued by the FDA. Mersalyl acid is currently replaced by less toxic non-mercury containing diuretics [L1575, L1577]. The sodium salt of a mercury-containing derivative of salicylamide, was formerly...
Experimental
ING-1
ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton epithelial cell adhesion molecule (EpCAM) glycoprotein that is expressed in high levels on most adenocarcinomas. It is an attractive target for immunotherapy.
Investigational
Matched Description: … ING-1 is a high-affinity, human engineered trade mark monoclonal antibody that recognizes a 40 kilodalton …
Vadimezan
Investigational
Nifuratel
Experimental
Matched Mixtures name: … MACMIROR COMPLEX ... MACMIROR COMPLEX ... INIMUR COMPLEX …
Rusalatide acetate
Chrysalin has been used in trials studying the treatment of Radius Fracture.
Investigational
Matched Categories: … Blood Coagulation Factors …
AC-100
AC-100 is a novel synthetic peptide derived from an endogenous human protein produced by bone and dental cells (a fragment from matrix extracellular phosphoglycoprotein). It is being developed by Acologix, Inc.
Investigational
Matched Description: … AC-100 is a novel synthetic peptide derived from an endogenous human protein produced by bone and dental …
ATG-Fresenius S
ATG-Fresenius S is a concentrated anti-human T-lymphocyte immunoglobulin preparation derived from rabbits after immunization with a T-lympoblast cell line. ATG-Fresenius S is an immunosuppressive product for the prevention and treatment of acute rejection following organ transplantation.
Investigational
Matched Description: … ATG-Fresenius S is a concentrated anti-human T-lymphocyte immunoglobulin preparation derived from rabbits …
AT-GTX-502
AT-GTX-502 is an experimental, one-time gene therapy that uses AAV9 to deliver a functional copy of CLN3.
Investigational
Matched Categories: … Non-Replicating Recombinant, Self-Complementary Adeno-Associated Virus Serotype 9 Containing the Human …
Tea tree oil
Tea tree oil is an essential oil derived mainly from the Australian native plant Melaleuca alternifolia via steam distillation of the of the leaves and terminal branches . It may be referred to as Melaleuca alternifolia oil. It has been a popular ingredient in a variety of household and cosmetic...
Experimental
Nutraceutical
Matched Categories: … Complex Mixtures …
XL765
XL765 is an orally available small molecule that has been shown in preclinical studies to selectively inhibit the activity of phosphoinositide-3 kinase (PI3K) and mammalian target of rapamycin (mTOR). It is being developed by Exelixis, Inc.
Investigational
AV-COVID-19
AV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor (GM-CSF).
The vaccine is created from the receiving patients’ isolated peripheral blood monocytes. The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2...
Investigational
Matched Description: … cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor …
Amelubant
Investigational
Displaying drugs 2351 - 2375 of 2957 in total